A body of work such as Pasteur's is inconceivable in our time: no man would be given a chance to create a whole science. Nowadays a path is scarcely opened up when the crowd begins to pour in.

Jigsaw Lady is the working title of a science fiction novel I've had in my head for darn near 15 years. I think I'll start work on it next year (in all my spare time) but I'd like to get it finished some day.

I got to spend all of my time every day at work reading and editing papers about cutting-edge technical research and getting paid for it. Then I'd go home at night and turn what I learned into science fiction stories.

I chose to deal with the science of cryptography. Cryptography began in mathematics. Codes were developed, even from Caesar's time, based on number theory and mathematical principles. I decided to use those principles and designed a work that is encoded.

There's a lot of work to do - not only the science but maintaining the facilities up here. When you go down from a crew of six to a crew of three, obviously you've lost half of your crew time available, so it does have an impact. But it's an impact we plan for.

This is a really big space station. We do a lot of various kinds of work here, different kinds of science experiments; we have over 400 different experiments going on at any one time in different areas, from basic science research to medical technology, that hopefully will benefit more people on Earth.

I think I set myself on a course to become a scientist around about the time that Carl Sagan's 'Cosmos' series was on television, and there really was no going back for me at that point, and then I went on to study space science and then get my Ph.D., then go aboard and work in the European Space Agency.

I knew I could always work harder and be better and show I'm more prepared. I had a whole science to, like, how you have to arrive 17 minutes early to something. If you're 20 minutes early, that means you're too eager, but 17 minutes gives you time to, like, settle, sign in, use the ladies' room, have some water, and get comfortable.

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