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We are seeing a new wave of young biologists that are attacking old problems with new tools and fresh ideas, leading to new types of bio startups and creating a much-needed engine to drive Silicon Valley into the next century.
Companies like Google and Facebook may offer jobs allowing or requiring imagination and creativity, but the whole of Silicon Valley accounts for only 3 percent of national income and a smaller percentage of national employment.
The problem is Silicon Valley, which is an amazing ecosystem, also ends up being an amazing bubble, with white guys talking to white guys about white-guy problems. So it's great, but you kind of miss a lot of things around you.
Silicon Valley has a lot of noise, a lot of hype. People are very excited about all of the Facebook stuff, Facebook applications. It's just been a huge hype over the last year when actually... there isn't really that much value.
By the time I was a senior in high school, I knew I wanted to move to Silicon Valley and learn more about computers and the Internet. I just fell in love with technology and the potential of everything the Internet had to offer.
My role on 'Silicon Valley' was so small that I didn't have a lot of influence anyway in the show. There are four guys who really write that show and run that show and then six or eight hanging out in a room kicking in a few bits.
What I found in Silicon Valley is an industry that's sort of been kept a very far remove from Washington and had an attitude of 'Just let us do our thing and make the miracles that people love around the world and leave us alone.'
I wouldn't put a big trust in what people in Silicon Valley say. They may be good at manipulating ones and zeroes and writing software, but beyond that, their contribution to human progress has been pretty dismal. I'm not impressed.
It was supposed to be a year or two just to refresh my batteries, but I moved to Silicon Valley in the early 90's, and one thing let to another, got very involved in high tech, and formed a company and it ended up doing pretty well.
Being in Silicon Valley makes me strict when it comes to my children's technology use. I am surrounded by it all day, so I try to avoid it when I get home. I set screen-time limits, because I think it's good to diversify activities.
I've spoken to people in Silicon Valley, and many times they have said to me, 'X storyline, or that thing that happened in your show - pretty much verbatim has happened to me.' And it's either identical or similar enough to be scary.
Silicon Valley is the engine for wealth creation. They've displaced energy, they've displaced financial services, and if we don't start including a broader array of people in that, the same group of people is going to rise to the top.
If you want to go and build a company that exists in Silicon Valley, then you should go and do it there. But if you want to build a company that is Australian, that represents your culture and your being, then you should do it in Sydney.
We founded Palantir in 2003-2004 because we perceived a giant gap between how the defense and intelligence community was harnessing technology to achieve its goals and what we had seen was possible in Silicon Valley over the last decade.
I don't think it's any secret that there's a lack of diversity in Silicon Valley. But that, to me, is actually quite beautiful. It allows me to be fully me because there is no one else to look at and say, 'Oh, I should be more like that.'
I think 'Settlers of Catan' is such a well-designed board game - it's the board game of entrepreneurship - that I made a knockoff called 'Startups of Silicon Valley.' It's literally - it's the same rules but just a different skin set to it.
The point of Silicon Valley, at least when I moved here, was we're all trying to do stuff, and none of us quite felt like we fit in anywhere else. But we were all trying to do good things. And the money was just the byproduct of good things.
My advice is never let a publicist call you a 'visionary.' I've hung out with the visionaries at the famed Xerox Palo Alto Research Center. I've been a successful Silicon Valley entrepreneur. I wouldn't touch 'visionary' with a 10-foot pole.
Because we're in a small town and somewhat isolated from the fast lane of high tech, we've been able to grow and concentrate on our work instead of being distracted by the competition and getting caught up in the soap opera of Silicon Valley.
At the end of the day, what makes Silicon Valley work is technology and the outcome of making money. Those two things have to be healthy. It has to matter a lot more than who is the celebrity and who is famous and who goes to the best parties.
Geeks are a critical driver of America's innovation ecosystem, from the entrepreneurs launching startups in Silicon Valley to the scientists experimenting in university research labs to the whiz kids building gadgets in their parents' garages.
What's been missing from regions outside of Silicon Valley is a 'playbook.' In American football, a playbook contains a sports team's strategies and plays. It struck me that every region needs its own industry playbook on how to compete globally.
What people often ask me is, 'What are the ingredients of Silicon Valley?' While the answer to that is complex, some of the ingredients I talk about are celebrating entrepreneurship, accepting failure, and embracing a mobile and diverse workforce.
It's often lost in most Silicon Valley startups, the importance of storytelling when most people are thinking about they assemble their team and the critical functions that the team needs to be successful. Storytelling is normally not on the list.
One of the great things about moving to Silicon Valley is that you're surrounded by all these people who've done it before. This place is an assembly line that takes a couple of twenty-somethings and walks you through everything you need to learn.
I think the high-tech industry is used to developing new things very quickly. It's the Silicon Valley way of doing business: You either move very quickly and you work hard to improve your product technology, or you get destroyed by some other company.
We who work in technology have nurtured an especially rare gift: the opportunity to effect change at an unprecedented scale and rate. Technology, community, and capitalism combine to make Silicon Valley the potential epicenter of vast positive change.
Some people have blithely dismissed growth in markets like China and India, saying Silicon Valley will always be the hub for tech: that everyone will come to us. Wake up: Because the numbers are showing money and talent is increasingly going elsewhere.
I moved to San Francisco when I was 20 years old. I couldn't even drink yet. My friends in college thought I was so stupid for missing out on the four best years of my life. But I was so ready to start living my own life and absorb Silicon Valley culture.
If you crave further confirmation that Silicon Valley is a magical place where magical thinking reigns, consider the tale of Roku, the video streaming company that filed to go public Friday, when alert people everywhere were headed out for a long weekend.
The iPhone will forever be associated with the inventive genius of Steve Jobs and Silicon Valley. But the roots of innovation can be traced back - from one genius to another, at least - back to the genius who put the phone in iPhone: Alexander Graham Bell.
Observe, orient, decide, act. It's fighter pilot terminology. If you have the faster OODA loop in a dogfight, you live. The other person dies. In Silicon Valley, the OODA loop of your decision-making is effectively what differentiates your ability to succeed.
The problems that you see startups tackling are dramatically different in different cities. Silicon Valley is unlikely to produce the same set of companies as New York or Cleveland because the region has a different set of strengths and defining institutions.
You have to live in Silicon Valley and hear the horror stories. You go and hang out at the cafes, and you meet entrepreneur after entrepreneur who's struggling, basically - who's had a visa problem who wants to start a company, but they can't start companies.
For a first-time entrepreneur, there's nothing better than being in Silicon Valley because there is so much going on, and there's such a large number of inventors, that even a B level idea or a C level idea could be nurtured and be given venture capital there.
When I came to the United States in 2004 to attend university at Stanford, I was instantly inspired by the stories and advice from startup leaders in Silicon Valley and beyond, who had endeavoured to create new opportunities and improve lives around the world.
The idea that there is a meritocracy where anyone from any background really might have the social and economic mobility to rise to the top in Silicon Valley, those are antithetical to a lot of the principles that the Trump administration apparently stands for.
If you want to invest in early-stage technologies, putting a timeframe on it does behold you to Silicon Valley economics. You've got a certain time period where you have to make the money. And you have to invest that money whether you find good companies or not.
Like all of us, I don't think Facebook is 100% evil, but there are aspects of it that move towards evilness. It's true of all the major Silicon Valley companies, that there are aspects to all of them that move towards evilness, but I don't believe they're 100% evil.
The director of the FBI has been visiting Silicon Valley companies asking them to build back doors so that it can spy on what is being said online. The Department of Commerce is going after piracy. At home, the American government wants anything but Internet freedom.
The reason why Silicon Valley is a worldwide innovation center is because it is a open culture that embraces diversity. You see people from all over the world. When you have many people from different backgrounds gathered together, that is where innovation comes from.
People are still very focused on the startup story: Risk-taking founders, with a bold idea, some capital and a network supportive environment, go out and take the shot on goal. But the problem is, this is no longer the truth about what makes Silicon Valley so special.
Baidu Research has three labs - two in Beijing that are already largely built up, and the Silicon Valley one is being built from scratch. We're hiring pretty rapidly, about one person a week, but we are about a month in, so honestly, we haven't done that much work yet.
Just as divine authority was legitimised by religious mythologies and human authority was legitimised by humanist ideologies, so high-tech gurus and Silicon Valley prophets are creating a new universal narrative that legitimises the authority of algorithms and Big Data.
I think there are four or five interesting pockets where a lot of cool technology companies are getting started. Chicago is one of them. New York is certainly another. Silicon Valley really dominates. And you're seeing some stuff out of Boston and Seattle and down South.
One thing I want to do is get Silicon Valley to think harder about those who have been left behind by the technology revolution. It has created huge winners for those who are able to understand it and are adept at it. But it has also displaced a tremendous number of jobs.
The emergence of Uber X was really the most important pivot maybe in the history of Silicon Valley. It's a vast majority of Uber's revenues, and so that flexibility and the rapid growth and the fighting the battles, it's all Travis. You can't take any credit away from him.
One of the issues we face here in San Francisco and Silicon Valley is a sense that the people all around us are as conversant in startup and tech culture as we are. But we need to remember, and remind ourselves repeatedly, that we're a small minority in a larger population.
A lot of the geeks in Silicon Valley will tell you they no longer believe in the ability of policymakers in Washington to accomplish anything. They don't understand why people end up in politics; they would do much more good for the world if they worked at Google or Facebook.
The number of African Americans in Silicon Valley is dismal. It's not up to one company - it's up to the entire industry to make sure that we are moving the conversation forward. Sometimes those walls of competition need to come down so we can move the entire industry forward.