In my opinion, the most significant works of the twentieth century are those that rise beyond the conceptual tyranny of genre; they are, at the same time, poetry, criticism, narrative, drama, etc.

Something very significant appears to be happening in America. There is a dramatic shift in voter affinity toward the GOP, and it may prove to be the mountain-too-high for Barack Obama's campaign.

We have significant work to be done. We have old, antiquated systems. Remember the 8-track tape player? Think of that as our core system, and we're living in a world where everybody has an iPhone.

Reconciliation cannot be used to pass comprehensive health care reform. It won't work because it was never designed for that kind of significant legislation; it was designed for deficit reduction.

The hundreds of thousands of illegal aliens who have unlawfully crossed our border are posing a significant threat to the government's ability to effectively enforce our nation's immigration laws.

In 2003, I had testicular cancer, and I didn't tell anyone about it - maybe five people. I had a fairly significant surgery. I was weak, slumped over. I told people at work I'd been in an accident.

I have always found that if, while creating an artwork, the artist constantly feels that some accident would occur if he is not careful, then it is a very significant moment and a significant work.

Technology has been advancing so fast that the number of jobs globally in manufacturing is declining. There is no way that Trump can bring significant numbers of manufacturing jobs back to the U.S.

Cereal production in the rain-fed areas still remains relatively unaffected by the impact of the green revolution, but significant change and progress are now becoming evident in several countries.

Substantially fewer films will be produced over the next year or two. And a significant portion of the production costs of the reduced slate will be borne by hedge funds and other investment groups.

I believe that the testing of the student's achievements in order to see if he meets some criterion held by the teacher, is directly contrary to the implications of therapy for significant learning.

I grew up in the '60s and '70s when men were required to wear a suit, shirt, and tie every day to be taken seriously. I was at the tail end of that generation, and it had a significant impact on me.

There can be no argument about the Lone Star State's significant contributions to American history, and we must remember the actions and the sacrifices of those who made Texas independence a reality.

We have actually experienced in recent months a dramatic demonstration of an unprecedented intelligence failure, perhaps the most significant intelligence failure in the history of the United States.

As you look around the country there are still a significant number of states where their whole school debate is over school funding and we've been focused on the quality debate for most of the '90s.

To be a Christian means you become a part of the most significant story the world has ever heard. You don't become part of that without an ongoing questioning of what it means to become part of that.

AT&T is interested in anything that drives more bandwidth requirements, and Apple TV drives significant bandwidth, and the iPhone drives significant bandwidth, and so I think it's a very logical fit.

I think what's different about this time is that at least pre-Internet there were more similarities between one generation and the next. And now, I think that gap has grown in a very significant way.

As best I can tell there was no advance warning of the attack on the World Trade Center in 1993, which was the first significant foreign terrorist activity in the U.S. No tip-offs that it was coming.

In this view, the role of the great majority of Americans is simply to buy the products produced, work happily for their wages, and leave all of the significant economic decisions to the capitalists.

In the absence of specific solutions or evidence that we have people in Washington, D.C., who can make a significant difference... people will cling to those who at least speak to their frustrations.

Over the next decade, there will be disruption as significant as the Internet was for publishing, where blockchain is going to disrupt dozens of industries, one being capital markets and Wall Street.

Particularly over the last few decades, technological innovation has offered opportunities to bring people and nations together - but it has also created significant new challenges to law enforcement.

From better access to American markets for our beef and lamb farmers, to cutting tariffs on dairy products like cheese, which are up to 17 per cent, there are significant opportunities for UK farming.

To be a writer was always my greatest aim. I remember writing a play about Guy Fawkes when I was 10. I suppose it's significant, at least to me, that my first work should be about a historical figure.

What is right? Simply put, it is any assignment in which the photographer has a significant spiritual stake... spiritually driven work constitutes the core of a photographer's contribution to culture.

Because there still exists a significant pay gap, women tend to earn less than men over the course of their lifetimes. Compounding the problem, women tend to spend less time in the workforce than men.

Whitesnake more than most rock bands would get a very significant percentage of women in the audience and those were the ones I'd hear the voices because from where I am on stage is a pretty good spot.

The homegrown terrorists are the most significant because any fighter returning from Syria to the United States would likely be identified and detected by our intelligence and law enforcement agencies.

I think one of the gorgeous things about TG is that we will go from something amazingly serious and important and significant in terms of the world and life, and then do something ludicrous and absurd.

I think that 'City of Heavenly Fire' is definitely a book where all the characters are tested to their limits, and they have to make really significant choices about who they are and who they wanna be.

The Irish move to a very low corporation tax has generated very significant revenue growth, considerably in excess of Britain's, where a slower economy has been combined with a number of stealth taxes.

Poetry is not mainstream, but then neither is serious fiction, really. But I don't think there's a lot to worry about in this particular 'problem'. Why does art have to be mainstream to be significant?

I've had five weddings but if I'm really honest and if I count significant de factos... I've had nine husbands... which sounds appalling but when you consider I started at 18 and I'm 65 it's not so bad.

This is the task, I think, of a letter movement. But it should be set up only in states where a significant response can be achieved, for a letter movement necessarily presupposes a strong organization.

Companies with significant revenue (more than $100 million) have, by definition, significant traction. They have proven out their thesis and can scale up or down as investment capital becomes available.

With the polarization of points of view around significant political and social issues, sports is a place where people can sort of talk about something together. And I think that is important to people.

Games can be art, and they can be significant and all the glorified things that we want them to be. But if you ask a kid if their toys are important, they'll say 'yes,' and 'Please don't take them away.'

Operation Northern Star with Canada has made significant progress in battling meth from the north, and we are engaged in numerous training opportunities in Mexico to help curb the problem from the south.

There is only one thing which can master the perplexed stuff of epic material into unity; and that is, an ability to see in particular human experience some significant symbolism of man's general destiny.

When I was in Marine training I memorised 'The Waste Land,' which was a significant experience in terms of really breaking apart language and thinking about how the different voices in that poem function.

The simplest and clearest motivation for taking animal welfare seriously is the recognition that pain is in and of itself a bad thing, and that to inflict significant amounts of it unnecessarily is wrong.

Most men, I am convinced, have an unmistakable feeling at the final moment of significant choice that they are making a free decision, that they can really decide which one of two or more roads to follow.

One of the biggest mistakes that founders can make is doing something that maybe seems like a great idea, and seems like a good use of time, but actually isn't measurable, significant, incremental growth.

I just try to find things that either need to be done, should be done, or where I can make a difference in a significant way. And the things I've been able to participate in have been very, very exciting.

Abortion is a searing and divisive public policy issue precisely because two significant sets of rights are in conflict, and no matter which set of laws it enacts, society must choose between those rights.

So-called 'complex carbs' may actually represent a more significant threat to health than simple sugar in that they may not only raise blood sugar, but keep it elevated for a more prolonged period of time.

Even Martin Luther and John Calvin believed that the Roman Catholic church, up to the Council of Trent, was basically orthodox - a true church with sound fundamental doctrines as well as significant error.

For me the much more significant question is what did the Americans do, if anything, to help the Croatian army, because they are the ones that changed fundamentally the map of Bosnia, not the Bosnian army.

The European auto industry made a commitment to reduce carbon dioxide emissions by an average of 140 grams per kilometer. But then there was a significant change in what customers wanted in their vehicles.

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