No Geologist worth anything is permanently bound to a desk or laboratory, but the charming notion that true science can only be based on unbiased observation of nature in the raw is mythology. Creative work, in geology and anywhere else, is interaction and synthesis: half-baked ideas from a bar room, rocks in the field, chains of thought from lonely walks, numbers squeezed from rocks in a laboratory, numbers from a calculator riveted to a desk, fancy equipment usually malfunctioning on expensive ships, cheap equipment in the human cranium, arguments before a road cut.

The principle of science, the definition, almost, is the following: The test of all knowledge is experiment. Experiment is the sole judge of scientific "truth." But what is the source of knowledge? Where do the laws that are to be tested come from? Experiment, itself, helps to produce these laws, in the sense that it gives us hints. But also needed is imagination to create from these hints the great generalizations--to guess at the wonderful, simple, but very strange patterns beneath them all, and then to experiment to check again whether we have made the right guess.

Or if the hypothesis were offered us of a world in which Messrs. Fourier's and Bellamy's and Morris's Utopias should all be outdone, and millions kept permanently happy on the one simple condition that a certain lost soul on the far-off edge of things should lead a life of lonely torment, what except a specifical and independent sort of emotion can it be which would make us immediately feel, even though an impulse arose within us to clutch at the happiness so offered, how hideous a thing would be its enjoyment when deliberately accepted as the fruit of such a bargain?

If the task of scientific methodology is to piece together an account of what scientists actually do, then the testimony of biologists should be heard with specially close attention. Biologists work very close to the frontier between bewilderment and understanding. Biology is complex, messy and richly various, like real life; it travels faster nowadays than physics or chemistry (which is just as well, since it has so much farther to go), and it travels nearer to the ground. It should therefore give us a specially direct and immediate insight into science in the making.

On consideration, it is not surprising that Darwin's finches should recognize their own kind primarily by beak characters. The beak is the only prominent specific distinction, and it features conspicuously both in attacking behaviour, when the birds face each other and grip beaks, and also in courtship, when food is passed from the beak of the male to the beak of the female. Hence though the beak differences are primarily correlated with differences in food, secondarily they serve as specific recognition marks, and the birds have evolved behaviour patterns to this end.

But although in theory physicists realize that their conclusions are ... not certainly true, this ... does not really sink into their consciousness. Nearly all the time ... they ... act as if Science were indisputably True, and what's more, as if only science were true.... Any information obtained otherwise than by the scientific method, although it may be true, the scientists will call "unscientific," using this word as a smear word, by bringing in the connotation from its original [Greek] meaning, to imply that the information is false, or at any rate slightly phony.

The statistical method is required in the interpretation of figures which are at the mercy of numerous influences, and its object is to determine whether individual influences can be isolated and their effects measured. The essence of the method lies in the determination that we are really comparing like with like, and that we have not overlooked a relevant factor which is present in Group A and absent from Group B. The variability of human beings in their illnesses and in their reactions to them is a fundamental reason for the planned clinical trial and not against it.

I have divers times examined the same matter (human semen) from a healthy man... not from a sick man... nor spoiled by keeping... for a long time and not liquefied after the lapse of some time... but immediately after ejaculation before six beats of the pulse had intervened; and I have seen so great a number of living animalcules... in it, that sometimes more than a thousand were moving about in an amount of material the size of a grain of sand... I saw this vast number of animalcules not all through the semen, but only in the liquid matter adhering to the thicker part.

While, on the one hand, the end of scientific investigation is the discovery of laws, on the other, science will have reached its highest goal when it shall have reduced ultimate laws to one or two, the necessity of which lies outside the sphere of our cognition. These ultimate laws-in the domain of physical science at least-will be the dynamical laws of the relations of matter to number, space, and time. The ultimate data will be number, matter, space, and time themselves. When these relations shall be known, all physical phenomena will be a branch of pure mathematics.

Even today a good many distinguished minds seem unable to accept or even to understand that from a source of noise natural selection alone and unaided could have drawn all the music of the biosphere. In effect natural selection operates upon the products of chance and can feed nowhere else; but it operates in a domain of very demanding conditions, and from this domain chance is barred. It is not to chance but to these conditions that eveloution owes its generally progressive cource, its successive conquests, and the impresssion it gives of a smooth and steady unfolding.

Our problem is that the climate crisis hatched in our laps at a moment in history when political and social conditions were uniquely hostile to a problem of this nature and magnitude-that moment being the tail end of the go-go '80s, the blastoff point for the crusade to spread deregulated capitalism around the world. Climate change is a collective problem demanding collective action the likes of which humanity has never actually accomplished. Yet it entered mainstream consciousness in the midst of an ideological war being waged on the very idea of the collective sphere.

Man is still by instinct a predatory animal given to devilish aggression. The discoveries of science have immensely increased productivity of material things. They have increased the standards of living and comfort. They have eliminated infinite drudgery. They have increased leisure. But that gives more time for devilment. The work of science has eliminated much disease and suffering. It has increased the length of life. That, together with increase in productivity, has resulted in vastly increased populations. Also it increased the number of people engaged in devilment.

Science begins with the world we have to live in, accepting its data and trying to explain its laws. From there, it moves toward the imagination: it becomes a mental construct, a model of a possible way of interpreting experience. The further it goes in this direction, the more it tends to speak the language of mathematics, which is really one of the languages of the imagination, along with literature and music. Art, on the other hand, begins with the world we construct, not with the world we see. It starts with the imagination, and then works toward ordinary experience.

For there is a great difference in delivery of the mathematics , which are the most abstracted of knowledges, and policy , which is the most immersed. And howsoever contention hath been moved , touching a uniformity of method in multiformity of matter, yet we see how that opinion, besides the weakness of it, hath been of ill desert towards learning, as that which taketh the way to reduce learning to certain empty and barren generalities; being but the very husks and shells of sciences, all the kernel being forced out and expulsed with the torture and press of the method.

To seek in the great accumulation of the already-said the text that resembles "in advance" a later text, to ransack history in order to rediscover the play of anticipations or echoes, to go right back to the first seeds or to go forward to the last traces, to reveal in a work its fidelity to tradition or its irreducible uniqueness, to raise or lower its stock of originality, to say that the Port -Royal grammarians invented nothing, or to discover that Cuvier had more predecessors than one thought, these are harmless enough amusements for historians who refuse to grow up.

As is well known the principle of virtual velocities transforms all statics into a mathematical assignment, and by D'Alembert's principle for dynamics, the latter is again reduced to statics. Although it is is very much in order that in gradual training of science and in the instruction of the individual the easier precedes the more difficult, the simple precedes the more complicated, the special precedes the general, yet the min, once it has arrived at the higher standpoint, demands the reverse process whereby all statics appears only as a very special case of mechanics.

We speak erroneously of "artificial" materials, "synthetics", and so forth. The basis for this erroneous terminology is the notion that Nature has made certain things which we call natural, and everything else is "man-made", ergo artificial. But what one learns in chemistry is that Nature wrote all the rules of structuring; man does not invent chemical structuring rules; he only discovers the rules. All the chemist can do is find out what Nature permits, and any substances that are thus developed or discovered are inherently natural. It is very important to remember that.

A rock or stone is not a subject that, of itself, may interest a philosopher to study; but, when he comes to see the necessity of those hard bodies, in the constitution of this earth, or for the permanency of the land on which we dwell, and when he finds that there are means wisely provided for the renovation of this necessary decaying part, as well as that of every other, he then, with pleasure, contemplates this manifestation of design, and thus connects the mineral system of this earth with that by which the heavenly bodies are made to move perpetually in their orbits.

During my span of life science has become a matter of public concern and the l'art pour l'art standpoint of my youth is now obsolete. Science has become an integral and most important part of our civilization, and scientific work means contributing to its development. Science in our technical age has social, economic, and political functions, and however remote one's own work is from technical application it is a link in the chain of actions and decisions which determine the fate of the human race. I realized this aspect of science in its full impact only after Hiroshima.

England and all civilised nations stand in deadly peril of not having enough to eat. As mouths multiply, food resources dwindle. Land is a limited quantity, and the land that will grow wheat is absolutely dependent on difficult and capricious natural phenomena... I hope to point a way out of the colossal dilemma. It is the chemist who must come to the rescue of the threatened communities. It is through the laboratory that starvation may ultimately be turned into plenty... The fixation of atmospheric nitrogen is one of the great discoveries, awaiting the genius of chemists.

Upon the whole, Chymistry is as yet but an opening science, closely connected with the usefull and ornamental arts, and worthy the attention of the liberal mind. And it must always become more and more so: for though it is only of late, that it has been looked upon in that light, the great progress already made in Chymical knowledge, gives us a pleasant prospect of rich additions to it. The Science is now studied on solid and rational grounds. While our knowledge is imperfect, it is apt to run into error: but Experiment is the thread that will lead us out of the labyrinth.

A parable: A man was examining the construction of a cathedral. He asked a stone mason what he was doing chipping the stones, and the mason replied, "I am making stones." He asked a stone carver what he was doing. "I am carving a gargoyle." And so it went, each person said in detail what they were doing. Finally he came to an old woman who was sweeping the ground. She said. "I am helping build a cathedral." ...Most of the time each person is immersed in the details of one special part of the whole and does not think of how what they are doing relates to the larger picture.

What struck me most in England was the perception that only those works which have a practical tendency awake attention and command respect, while the purely scientific, which possess far greater merit are almost unknown. And yet the latter are the proper source from which the others flow. Practice alone can never lead to the discovery of a truth or a principle. In Germany it is quite the contrary. Here in the eyes of scientific men no value, or at least but a trifling one, is placed upon the practical results. The enrichment of science is alone considered worthy attention.

Natural causes, as we know, are at work, which tend to modify, if they do not at length destroy, all the arrangements and dimensions of the earth and the whole solar system. But though in the course of ages catastrophes have occurred and may yet occur in the heavens, though ancient systems may be dissolved and new systems evolved out of their ruins, the molecules [i.e. atoms] out of which these systems are built-the foundation stones of the material universe-remain unbroken and unworn.‎ They continue to this day as they were created-perfect in number and measure and weight.

During the time that [Karl] Landsteiner gave me an education in the field of imununology, I discovered that he and I were thinking about the serologic problem in very different ways. He would ask, What do these experiments force us to believe about the nature of the world? I would ask, What is the most. simple and general picture of the world that we can formulate that is not ruled by these experiments? I realized that medical and biological investigators were not attacking their problems the same way that theoretical physicists do, the way I had been in the habit of doing.

Edison was by far the most successful and, probably, the last exponent of the purely empirical method of investigation. Everything he achieved was the result of persistent trials and experiments often performed at random but always attesting extraordinary vigor and resource. Starting from a few known elements, he would make their combinations and permutations, tabulate them and run through the whole list, completing test after test with incredible rapidity until he obtained a clue. His mind was dominated by one idea, to leave no stone unturned, to exhaust every possibility.

Wherefore also these Kinds [elements] occupied different places even before the universe was organised and generated out of them. Before that time, in truth, all these were in a state devoid of reason or measure, but when the work of setting in order this Universe was being undertaken, fire and water and earth and air, although possessing some traces of their known nature, were yet disposed as everything is likely to be in the absence of God; and inasmuch as this was then their natural condition, God began by first marking them out into shapes by means of forms and numbers.

The hypotheses which we accept ought to explain phenomena which we have observed. But they ought to do more than this; our hypotheses ought to foretell phenomena which have not yet been observed; ... because if the rule prevails, it includes all cases; and will determine them all, if we can only calculate its real consequences. Hence it will predict the results of new combinations, as well as explain the appearances which have occurred in old ones. And that it does this with certainty and correctness, is one mode in which the hypothesis is to be verified as right and useful.

The Author of nature has not given laws to the universe, which, like the institutions of men, carry in themselves the elements of their own destruction; he has not permitted in his works any symptom of infancy or of old age, or any sign by which we may estimate either their future or their past duration. He may put an end, as he no doubt gave a beginning, to the present system at some determinate period of time; but we may rest assured, that this great catastrophe will not be brought about by the laws now existing, and that it is not indicated by any thing which we perceive.

Therefore the solid body of the earth is reasonably considered as being the largest relative to those moving against it and as remaining unmoved in any direction by the force of the very small weights, and as it were absorbing their fall. And if it had some one common movement, the same as that of the other weights, it would clearly leave them all behind because of its much greater magnitude. And the animals and other weights would be left hanging in the air, and the earth would very quickly fallout of the heavens. Merely to conceive such things makes them appear ridiculous.

If diphtheria is a disease caused by a microorganism, it is essential that three postulates be fulfilled. The fulfilment of these postulates is necessary in order to demonstrate strictly the parasitic nature of a disease: 1) The organism must be shown to be constantly present in characteristic form and arrangement in the diseased tissue. 2) The organism which, from its behaviour appears to be responsible for the disease, must be isolated and grown in pure culture. 3) The pure culture must be shown to induce the disease experimentally. An early statement of Koch's postulates.

As I have already urged, the practice of that which is ethically best - what we call goodness or virtue - involves a course of conduct which, in all respects, is opposed to that which leads to success in the cosmic struggle for existence. In place of ruthless selfassertion it demands self-restraint; in place of thrusting aside, or treading down, all competitors, it requires that the individual shall not merely respect , but shall help his fellows. It repudiates the gladiatorial theory of existence. Laws and moral precepts are directed to the end of curbing the cosmic process.

But what exceeds all wonders, I have discovered four new planets and observed their proper and particular motions, different among themselves and from the motions of all the other stars; and these new planets move about another very large star [Jupiter] like Venus and Mercury, and perchance the other known planets, move about the Sun. As soon as this tract, which I shall send to all the philosophers and mathematicians as an announcement, is finished, I shall send a copy to the Most Serene Grand Duke, together with an excellent spyglass, so that he can verify all these truths.

The first effect of the mind growing cultivated is that processes once multiple get to be performed in a single act. Lazarus has called this the progressive "condensation" of thought. ... Steps really sink from sight. An advanced thinker sees the relations of his topics is such masses and so instantaneously that when he comes to explain to younger minds it is often hard ... Bowditch, who translated and annotated Laplace's Méchanique Céleste, said that whenever his author prefaced a proposition by the words "it is evident," he knew that many hours of hard study lay before him.

Having always observed that most of them who constantly took in the weekly Bills of Mortality made little other use of them than to look at the foot how the burials increased or decreased, and among the Casualties what had happened, rare and extraordinary, in the week current; so as they might take the same as a Text to talk upon in the next company, and withal in the Plague-time, how the Sickness increased or decreased, that the Rich might judg of the necessity of their removal, and Trades-men might conjecture what doings they were likely to have in their respective dealings.

One of the grandest figures that ever frequented Eastern Yorkshire was William Smith, the distinguished Father of English Geology. My boyish reminiscence of the old engineer, as he sketched a triangle on the flags of our yard, and taught me how to measure it, is very vivid. The drab knee-breeches and grey worsted stockings, the deep waistcoat, with its pockets well furnished with snuff-of which ample quantities continually disappeared within the finely chiselled nostril-and the dark coat with its rounded outline and somewhat quakerish cut, are all clearly present to my memory.

But shall gravity be therefore called an occult cause, and thrown out of philosophy, because the cause of gravity is occult and not yet discovered? Those who affirm this, should be careful not to fall into an absurdity that may overturn the foundations of all philosophy. For causes usually proceed in a continued chain from those that are more compounded to those that are more simple; when we are arrived at the most simple cause we can go no farther ... These most simple causes will you then call occult and reject them? Then you must reject those that immediately depend on them.

Mere numbers cannot bring out ... the intimate essence of the experiment. This conviction comes naturally when one watches a subject at work. ... What things can happen! What reflections, what remarks, what feelings, or, on the other hand, what blind automatism, what absence of ideas! ... The experimenter judges what may be going on in [the subject's] mind, and certainly feels difficulty in expressing all the oscillations of a thought in a simple, brutal number, which can have only a deceptive precision. How, in fact, could it sum up what would need several pages of description!

The fact that Science walks forward on two feet, namely theory and experiment, is nowhere better illustrated than in the two fields for slight contributions to which you have done me the great honour of awarding the the Nobel Prize in Physics for the year 1923. Sometimes it is one foot that is put forward first, sometimes the other, but continuous progress is only made by the use of both-by theorizing and then testing, or by finding new relations in the process of experimenting and then bringing the theoretical foot up and pushing it on beyond, and so on in unending alterations.

My mind seems to have become a kind of machine for grinding general laws out of large collections of facts, but why this should have caused the atrophy of that part of the brain that alone on which the higher tastes depend, I cannot conceive. A man with a mind more highly organised or better constituted than mine would not, I suppose, have thus suffered, and if I had to live my life over again, I would have made a rule to read some poetry and listen to some music at least once every week; for perhaps the parts of my brain now atrophied would thus have been kept alive through use.

We have simply arrived too late in the history of the universe to see this primordial simplicity easily... But although the symmetries are hidden from us, we can sense that they are latent in nature, governing everything about us. That's the most exciting idea I know: that nature is much simpler than it looks. Nothing makes me more hopeful that our generation of human beings may actually hold the key to the universe in our hands - that perhaps in our lifetimes we may be able to tell why all of what we see in this immense universe of galaxies and particles is logically inevitable.

The scientist has to take 95 per cent of his subject on trust. He has to because he can't possibly do all the experiments, therefore he has to take on trust the experiments all his colleagues and predecessors have done. Whereas a mathematician doesn't have to take anything on trust. Any theorem that's proved, he doesn't believe it, really, until he goes through the proof himself, and therefore he knows his whole subject from scratch. He's absolutely 100 per cent certain of it. And that gives him an extraordinary conviction of certainty, and an arrogance that scientists don't have.

Kepler's discovery would not have been possible without the doctrine of conics. Now contemporaries of Kepler-such penetrating minds as Descartes and Pascal-were abandoning the study of geometry ... because they said it was so UTTERLY USELESS. There was the future of the human race almost trembling in the balance; for had not the geometry of conic sections already been worked out in large measure, and had their opinion that only sciences apparently useful ought to be pursued, the nineteenth century would have had none of those characters which distinguish it from the ancien régime.

We are in the presence of a recruiting drive systematically and deliberately undertaken by American business, by American universities, and to a lesser extent, American government, often initiated by talent scouts specially sent over here to buy British brains and preempt them for service of the U.S.A. ... I look forward earnestly to the day when some reform of the American system of school education enables them to produce their own scientists so that, in an aimiable free trade of talent, there may be adequate interchange between our country and theirs, and not a one-way traffic.

Let me tell you how at one time the famous mathematician Euclid became a physician. It was during a vacation, which I spent in Prague as I most always did, when I was attacked by an illness never before experienced, which manifested itself in chilliness and painful weariness of the whole body. In order to ease my condition I took up Euclid's Elements and read for the first time his doctrine of ratio, which I found treated there in a manner entirely new to me. The ingenuity displayed in Euclid's presentation filled me with such vivid pleasure, that forthwith I felt as well as ever.

O. Hahn and F. Strassmann have discovered a new type of nuclear reaction, the splitting into two smaller nuclei of the nuclei of uranium and thorium under neutron bombardment. Thus they demonstrated the production of nuclei of barium, lanthanum, strontium, yttrium, and, more recently, of xenon and caesium. It can be shown by simple considerations that this type of nuclear reaction may be described in an essentially classical way like the fission of a liquid drop, and that the fission products must fly apart with kinetic energies of the order of hundred million electron-volts each.

Sciences usually advances by a succession of small steps, through a fog in which even the most keen-sighted explorer can seldom see more than a few paces ahead. Occasionally the fog lifts, an eminence is gained, and a wider stretch of territory can be surveyed-sometimes with startling results. A whole science may then seem to undergo a kaleidoscopic rearrangement, fragments of knowledge sometimes being found to fit together in a hitherto unsuspected manner. Sometimes the shock of readjustment may spread to other sciences; sometimes it may divert the whole current of human thought.

I have spent much time in the study of the abstract sciences; but the paucity of persons with whom you can communicate on such subjects disgusted me with them. When I began to study man, I saw that these abstract sciences are not suited to him, and that in diving into them, I wandered farther from my real object than those who knew them not, and I forgave them for not having attended to these things. I expected then, however, that I should find some companions in the study of man, since it was so specifically a duty. I was in error. There are fewer students of man than of geometry.

The traditional boundaries between various fields of science are rapidly disappearing and what is more important science does not know any national borders. The scientists of the world are forming an invisible network with a very free flow of scientific information - a freedom accepted by the countries of the world irrespective of political systems or religions. ... Great care must be taken that the scientific network is utilized only for scientific purposes - if it gets involved in political questions it loses its special status and utility as a nonpolitical force for development.

Doctor Johnson said, that in sickness there were three things that were material; the physician, the disease, and the patient: and if any two of these joined, then they get the victory; for, Ne Hercules quidem contra duos [Not even Hercules himself is a match for two]. If the physician and the patient join, then down goes the disease; for then the patient recovers: if the physician and the disease join, that is a strong disease; and the physician mistaking the cure, then down goes the patient: if the patient and the disease join, then down goes the physician; for he is discredited.

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