And, to prevent mistakes, I must advertize you, that I now mean by elements, as those chymists that speak plainest do by their principles, certain primitive or simple, or perfectly unmingled bodies; which not being made of any other bodies, or of one another, are the ingredients of which all those called perfectly mixt bodies are immediately compounded, and into which they are ultimately resolved: now whether there be any such body to be constantly met with in all, and each, of those that are said to be elemented bodies, is the thing I now question.

No occupation is more worthy of an intelligent and enlightened mind, than the study of Nature and natural objects; and whether we labour to investigate the structure and function of the human system, whether we direct our attention to the classification and habits of the animal kingdom, or prosecute our researches in the more pleasing and varied field of vegetable life, we shall constantly find some new object to attract our attention, some fresh beauties to excite our imagination, and some previously undiscovered source of gratification and delight.

The earth's becoming at a particular period the residence of human beings, was an era in the moral, not in the physical world, that our study and contemplation of the earth, and the laws which govern its animate productions, ought no more to be considered in the light of a disturbance or deviation from the system, than the discovery of the satellites of Jupiter should be regarded as a physical event in the history of those heavenly bodies, however influential they may have become from that time in advancing the progress of sound philosophy among men.

The pursuit of science has often been compared to the scaling of mountains, high and not so high. But who amongst us can hope, even in imagination, to scale the Everest and reach its summit when the sky is blue and the air is still, and in the stillness of the air survey the entire Himalayan range in the dazzling white of the snow stretching to infinity? None of us can hope for a comparable vision of nature and of the universe around us. But there is nothing mean or lowly in standing in the valley below and awaiting the sun to rise over Kinchinjunga.

I fancy you give me credit for being a more systematic sort of cove than I really am in the matter of limits of significance. What would actually happen would be that I should make out Pt (normal) and say to myself that would be about 50:1; pretty good but as it may not be normal we'd best not be too certain, or 100:1; even allowing that it may not be normal it seems good enough and whether one would be content with that or would require further work would depend on the importance of the conclusion and the difficulty of obtaining suitable experience.

After having produced aquatic animals of all ranks and having caused extensive variations in them by the different environments provided by the waters, nature led them little by little to the habit of living in the air, first by the water's edge and afterwards on all the dry parts of the globe. These animals have in course of time been profoundly altered by such novel conditions; which so greatly influenced their habits and organs that the regular gradation which they should have exhibited in complexity of organisation is often scarcely recognisable.

But, contrary to the lady's prejudices about the engineering profession, the fact is that quite some time ago the tables were turned between theory and applications in the physical sciences. Since World War II the discoveries that have changed the world are not made so much in lofty halls of theoretical physics as in the less-noticed labs of engineering and experimental physics. The roles of pure and applied science have been reversed; they are no longer what they were in the golden age of physics, in the age of Einstein, Schrödinger, Fermi and Dirac.

What the founders of modern science ... had to do, was not criticize and to combat certain faulty theories, and to correct or to replace them by better ones. They had to do something quite different. They had to destroy one world and replace it by another. They had to reshape the framework of our intellect itself, to restate and to reform its concepts, to evolve a new approach to Being, a new concept of knowledge, and a new concept of science - and even to replace a pretty natural approach, that of common sense, by another which is not natural at all.

The evidence from both approaches, statistical and experimental, does not appear sufficiently significant to me to warrant forsaking the pleasure of smoking. As a matter of fact, if the investigations had been pointed toward some material that I thoroughly dislike, such as parsnips, I still would not feel that evidence of the type presented constituted a reasonable excuse for eliminating the things from my diet. I will still continue to smoke, and if the tobacco companies cease manufacturing their product, I will revert to sweet fern and grape leaves.

In that memorable year, 1822: Oersted, a Danish physicist, held in his hands a piece of copper wire, joined by its extremities to the two poles of a Volta pile. On his table was a magnetized needle on its pivot, and he suddenly saw (by chance you will say, but chance only favours the mind which is prepared) the needle move and take up a position quite different from the one assigned to it by terrestrial magnetism. A wire carrying an electric current deviates a magnetized needle from its position. That, gentlemen, was the birth of the modern telegraph.

Beware the irrational, however seductive. Shun the 'transcendent' and all who invite you to subordinate or annihilate yourself. Distrust compassion; prefer dignity for yourself and others. Don't be afraid to be thought arrogant or selfish. Picture all experts as if they were mammals. Never be a spectator of unfairness or stupidity. Seek out argument and disputation for their own sake; the grave will supply plenty of time for silence. Suspect your own motives, and all excuses. Do not live for others any more than you would expect others to live for you.

Every scientist, through personal study and research, completes himself and his own humanity. ... Scientific research constitutes for you, as it does for many, the way for the personal encounter with truth, and perhaps the privileged place for the encounter itself with God, the Creator of heaven and earth. Science shines forth in all its value as a good capable of motivating our existence, as a great experience of freedom for truth, as a fundamental work of service. Through research each scientist grows as a human being and helps others to do likewise.

It seems a miracle that young children easily learn the language of any environment into which they were born. The generative approach to grammar, pioneered by Chomsky, argues that this is only explicable if certain deep, universal features of this competence are innate characteristics of the human brain. Biologically speaking, this hypothesis of an inheritable capability to learn any language means that it must somehow be encoded in the DNA of our chromosomes. Should this hypothesis one day be verified, then lingusitics would become a branch of biology.

But medicine has long had all its means to hand, and has discovered both a principle and a method, through which the discoveries made during a long period are many and excellent, while full discovery will be made, if the inquirer be competent, conduct his researches with knowledge of the discoveries already made, and make them his starting-point. But anyone who, casting aside and rejecting all these means, attempts to conduct research in any other way or after another fashion, and asserts that he has found out anything, is and has been victim of deception.

The concept of an independent system is a pure creation of the imagination. For no material system is or can ever be perfectly isolated from the rest of the world. Nevertheless it completes the mathematician's "blank form of a universe" without which his investigations are impossible. It enables him to introduce into his geometrical space, not only masses and configurations, but also physical structure and chemical composition. Just as Newton first conclusively showed that this is a world of masses, so Willard Gibbs first revealed it as a world of systems.

Imagine a room awash in gasoline, and there are two implacable enemies in that room. One of them has nine thousand matches. The other has seven thousand matches. Each of them is concerned about who's ahead, who's stronger. Well that's the kind of situation we are actually in. The amount of weapons that are available to the United States and the Soviet Union are so bloated, so grossly in excess of what's needed to dissuade the other, that if it weren't so tragic, it would be laughable. What is necessary is to reduce the matches and to clean up the gasoline.

I was working with these very long-chain ... extended-chain polymers, where you had a lot of benzene rings in them. ... Transforming a polymer solution from a liquid to a fiber requires a process called spinning. ... We spun it and it spun beautifully. It [Kevlar] was very strong and very stiff-unlike anything we had made before. I knew that I had made a discovery. I didn't shout "Eureka!" but I was very excited, as was the whole laboratory excited, and management was excited, because we were looking for something new. Something different. And this was it.

It is more important to have beauty in one's equations than to have them fit experiment... It seems that if one is working from the point of view of getting beauty in one's equations, and if one has really a sound insight, one is on a sure line of progress. If there is not complete agreement between the results of one's work and experiment, one should not allow oneself to be too discouraged, because the discrepancy may well be due to minor features that are not properly taken into account and that will get cleared up with further developments of the theory.

An Individual, whatever species it might be, is nothing in the Universe. A hundred, a thousand individuals are still nothing. The species are the only creatures of Nature, perpetual creatures, as old and as permanent as it. In order to judge it better, we no longer consider the species as a collection or as a series of similar individuals, but as a whole independent of number, independent of time, a whole always living, always the same, a whole which has been counted as one in the works of creation, and which, as a consequence, makes only a unity in Nature.

In astronomy, the law of gravitation is plainly better worth knowing than the position of a particular planet on a particular night, or even on every night throughout a year. There are in the law a splendour and simplicity and sense of mastery which illuminate a mass of otherwise uninteresting details. But in history the matter is far otherwise. Historical facts, many of them, have an intrinsic value, a profound interest on their own account, which makes them worthy of study, quite apart from any possibility of linking them together by means of causal laws.

Historical chronology, human or geological, depends... upon comparable impersonal principles. If one scribes with a stylus on a plate of wet clay two marks, the second crossing the first, another person on examining these marks can tell unambiguously which was made first and which second, because the latter event irreversibly disturbs its predecessor. In virtue of the fact that most of the rocks of the earth contain imprints of a succession of such irreversible events, an unambiguous working out of the chronological sequence of these events becomes possible.

The breaking up of the terrestrial globe, this it is we witness. It doubtless began a long time ago, and the brevity of human life enables us to contemplate it without dismay. It is not only in the great mountain ranges that the traces of this process are found. Great segments of the earth's crust have sunk hundreds, in some cases, even thousands, of feet deep, and not the slightest inequality of the surface remains to indicate the fracture; the different nature of the rocks and the discoveries made in mining alone reveal its presence. Time has levelled all.

They have never affirm'd any thing, concerning the cause, till the trial was past: whereas, to do it before, is a most venomous thing in the making of Sciences: for whoever has fix'd on his Cause, before he has experimented; can hardly avoid fitting his Experiment, and his Observations, to his Own Cause, which he had before imagin'd; rather than the Cause to the Truth of the Experiment itself. Referring to experiments of the Aristotelian mode, whereby a preconceived truth would be illustrated merely to convince people of the validity of the original thought.

A hundred years ago, Auguste Compte, ... a great philosopher, said that humans will never be able to visit the stars, that we will never know what stars are made out of, that that's the one thing that science will never ever understand, because they're so far away. And then, just a few years later, scientists took starlight, ran it through a prism, looked at the rainbow coming from the starlight, and said: "Hydrogen!" Just a few years after this very rational, very reasonable, very scientific prediction was made, that we'll never know what stars are made of.

Knowledge signifies things known. Where there are no things known, there is no knowledge. Where there are no things to be known, there can be no knowledge. We have observed that every science, that is, every branch of knowledge, is compounded of certain facts, of which our sensations furnish the evidence. Where no such evidence is supplied, we are without data; we are without first premises; and when, without these, we attempt to build up a science, we do as those who raise edifices without foundations. And what do such builders construct? Castles in the air.

I do not ... reject the use of statistics in medicine, but I condemn not trying to get beyond them and believing in statistics as the foundation of medical science. ... Statistics ... apply only to cases in which the cause of the facts observed is still [uncertain or] indeterminate. ... There will always be some indeterminism ... in all the sciences, and more in medicine than in any other. But man's intellectual conquest consists in lessening and driving back indeterminism in proportion as he gains ground for determinism by the help of the experimental method.

GOOSE, n. A bird that supplies quills for writing. These, by some occult process of nature, are penetrated and suffused with various degrees of the bird's intellectual energies and emotional character, so that when inked and drawn mechanically across paper by a person called an "author," there results a very fair and accurate transcript of the fowl's thought and feeling. The difference in geese, as discovered by this ingenious method, is considerable: many are found to have only trivial and insignificant powers, but some are seen to be very great geese indeed.

This new force, which was unknown until now, is common to organic and inorganic nature. I do not believe that this is a force entirely independent of the electrochemical affinities of matter; I believe, on the contrary, that it is only a new manifestation, but since we cannot see their connection and mutual dependence, it will be easier to designate it by a separate name. I will call this force catalytic force. Similarly, I will call the decomposition of bodies by this force catalysis, as one designates the decomposition of bodies by chemical affinity analysis.

The whole subject of the X rays is opening out wonderfully, Bragg has of course got in ahead of us, and so the credit all belongs to him, but that does not make it less interesting. We find that an X ray bulb with a platinum target gives out a sharp line spectrum of five wavelengths which the crystal separates out as if it were a diffraction grating. In this way one can get pure monochromatic X rays. Tomorrow we search for the spectra of other elements. There is here a whole new branch of spectroscopy, which is sure to tell one much about the nature of an atom.

There is a conceptual depth as well as a purely visual depth. The first is discovered by science; the second is revealed in art. The first aids us in understanding the reasons of things; the second in seeing their forms. In science we try to trace phenomena back to their first causes, and to general laws and principles. In art we are absorbed in their immediate appearance, and we enjoy this appearance to the fullest extent in all its richness and variety. Here we are not concerned with the uniformity of laws but with the multiformity and diversity of intuitions.

It is clear, then, that the idea of a fixed method, or of a fixed theory of rationality, rests on too naive a view of man and his social surroundings. To those who look at the rich material provided by history, and who are not intent on impoverishing it in order to please their lower instincts, their craving for intellectual security in the form of clarity, precision, "objectivity," "truth," it will become clear that there is only one principle that can be defended under all circumstances and in all stages of human development. It is the principle: anything goes.

I then began to study arithmetical questions without any great apparent result, and without suspecting that they could have the least connexion with my previous researches. Disgusted at my want of success, I went away to spend a few days at the seaside, and thought of entirely different things. One day, as I was walking on the cliff, the idea came to me, again with the same characteristics of conciseness, suddenness, and immediate certainty, that arithmetical transformations of indefinite ternary quadratic forms are identical with those of non-Euclidian geometry.

Wonder [admiratio astonishment, marvel] is a kind of desire for knowledge. The situation arises when one sees an effect and does not know its cause, or when the cause of the particular effect is one that exceeds his power of understanding. Hence, wonder is a cause of pleasure insofar as there is annexed the hope of attaining understanding of that which one wants to know. ... For desire is especially aroused by the awareness of ignorance, and consequently a man takes the greatest pleasure in those things which he discovers for himself or learns from the ground up.

With crystals we are in a situation similar to an attempt to investigate an optical grating merely from the spectra it produces... But a knowledge of the positions and intensities of the spectra does not suffice for the determination of the structure. The phases with which the diffracted waves vibrate relative to one another enter in an essential way. To determine a crystal structure on the atomic scale, one must know the phase differences between the different interference spots on the photographic plate, and this task may certainly prove to be rather difficult.

The history of this paper suggests that highly speculative investigations, especially by an unknown author, are best brought before the world through some other channel than a scientific society, which naturally hesitates to admit into its printed records matters of uncertain value. Perhaps one may go further and say that a young author who believes himself capable of great things would usually do well to secure the favourable recognition of the scientific world by work whose scope is limited and whose value is easily judged, before embarking upon higher flights.

The question whether atoms exist or not... belongs rather to metaphysics. In chemistry we have only to decide whether the assumption of atoms is an hypothesis adapted to the explanation of chemical phenomena... whether a further development of the atomic hypothesis promises to advance our knowledge of the mechanism of chemical phenomena... I rather expect that we shall some day find, for what we now call atoms, a mathematico-mechanical explanation, which will render an account of atomic weight, of atomicity, and of numerous other properties of the so-called atoms.

For the sake of our children and our future, we must do more to combat climate change. Now, it's true that no single event makes a trend. But the fact is the 12 hottest years on record have all come in the last 15. Heat waves, droughts, wildfires, floods-all are now more frequent and more intense. We can choose to believe that Superstorm Sandy, and the most severe drought in decades, and the worst wildfires some states have ever seen were all just a freak coincidence. Or we can choose to believe in the overwhelming judgment of science-and act before it's too late.

The object of geometry in all its measuring and computing, is to ascertain with exactness the plan of the great Geometer, to penetrate the veil of material forms, and disclose the thoughts which lie beneath them? When our researches are successful, and when a generous and heaven-eyed inspiration has elevated us above humanity, and raised us triumphantly into the very presence, as it were, of the divine intellect, how instantly and entirely are human pride and vanity repressed, and, by a single glance at the glories of the infinite mind, are we humbled to the dust.

"The Universe repeats itself, with the possible exception of history." Of all earthly studies history is the only one that does not repeat itself. ... Astronomy repeats itself; botany repeats itself; trigonometry repeats itself; mechanics repeats itself; compound long division repeats itself. Every sum if worked out in the same way at any time will bring out the same answer. ... A great many moderns say that history is a science; if so it occupies a solitary and splendid elevation among the sciences; it is the only science the conclusions of which are always wrong.

It has been said by a distinguished philosopher that England is "usually the last to enter into the general movement of the European mind." The author of the remark probably meant to assert that a man or a system may have become famous on the continent, while we are almost ignorant of the name of the man and the claims of his system. Perhaps, however, a wider range might be given to the assertion. An exploded theory or a disadvantageous practice, like a rebel or a patriot in distress, seeks refuge on our shores to spend its last days in comfort if not in splendour.

There is little chance that aliens from two societies anywhere in the Galaxy will be culturally close enough to really 'get along.' This is something to ponder as you watch the famous cantina scene in Star Wars. ... Does this make sense, given the overwhelmingly likely situation that galactic civilizations differ in their level of evolutionary development by thousands or millions of years? Would you share drinks with a trilobite, an ourang-outang, or a saber-toothed tiger? Or would you just arrange to have a few specimens stuffed and carted off to the local museum?

You must not say that this cannot be, or that that is contrary to nature. You do not know what Nature is, or what she can do; and nobody knows; not even Sir Roderick Murchison, or Professor Huxley, or Mr. Darwin, or Professor Faraday, or Mr. Grove, or any other of the great men whom good boys are taught to respect. They are very wise men; and you must listen respectfully to all they say: but even if they should say, which I am sure they never would, 'That cannot exist. That is contrary to nature,' you must wait a little, and see; for perhaps even they may be wrong.

Here's a simple experiment that you might want to try if there is absolutely nothing else going on in your life. All you need is a cork, a bar magnet, and a pail of water. Simply attach your magnet to your cork, then drop it into the water, and voilà (literally, "you have a compass")-you have a compass. How does it work? Simple. Notice that, no matter which way you turn the bucket, the cork always floats on top of the water (unless the magnet is too heavy). Using this scientific principle, early hardy mariners were able to tell at a glance whether they were sinking!

[P]olitical and social and scientific values ... should be correlated in some relation of movement that could be expressed in mathematics, nor did one care in the least that all the world said it could not be done, or that one knew not enough mathematics even to figure a formula beyond the schoolboy s=(1/2)gt2. If Kepler and Newton could take liberties with the sun and moon, an obscure person ... could take liberties with Congress, and venture to multiply its attraction into the square of its time. He had only to find a value, even infinitesimal, for its attraction.

As I considered the matter carefully it gradually came to light that all those matters only were referred to mathematics in which order and measurements are investigated, and that it makes no difference whether it be in numbers, figures, stars, sounds or any other object that the question of measurement arises. I saw consequently that there must be some general science to explain that element as a whole which gives rise to problems about order and measurement, restricted as these are to no special subject matter. This, I perceived was called 'universal mathematics'.

Undeveloped though the science [of chemistry] is, it already has great power to bring benefits. Those accruing to physical welfare are readily recognized, as in providing cures, improving the materials needed for everyday living, moving to ameliorate the harm which mankind by its sheer numbers does to the environment, to say nothing of that which even today attends industrial development. And as we continue to improve our understanding of the basic science on which applications increasingly depend, material benefits of this and other kinds are secured for the future.

The first [quality] to be named must always be the power of attention, of giving one's whole mind to the patient without the interposition of anything of oneself. It sounds simple but only the very greatest doctors ever fully attain it. ... The second thing to be striven for is intuition. This sounds an impossibility, for who can control that small quiet monitor? But intuition is only interference from experience stored and not actively recalled. ... The last aptitude I shall mention that must be attained by the good physician is that of handling the sick man's mind.

To this day, we see all around us the Promethean drive to omnipotence through technology and to omniscience through science. The effecting of all things possible and the knowledge of all causes are the respective primary imperatives of technology and of science. But the motivating imperative of society continues to be the very different one of its physical and spiritual survival. It is now far less obvious than it was in Francis Bacon's world how to bring the three imperatives into harmony, and how to bring all three together to bear on problems where they superpose.

Nature is the system of laws established by the Creator for the existence of things and for the succession of creatures. Nature is not a thing, because this thing would be everything. Nature is not a creature, because this creature would be God. But one can consider it as an immense vital power, which encompasses all, which animates all, and which, subordinated to the power of the first Being, has begun to act only by his order, and still acts only by his concourse or consent ... Time, space and matter are its means, the universe its object, motion and life its goal.

There must be no barriers to freedom of inquiry... There is no place for dogma in science. The scientist is free, and must be free to ask any question, to doubt any assertion, to seek for any evidence, to correct any errors. Our political life is also predicated on openness. We know that the only way to avoid error is to detect it and that the only way to detect it is to be free to inquire. And we know that as long as men are free to ask what they must, free to say what they think, free to think what they will, freedom can never be lost, and science can never regress.

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