Quotes of All Topics . Occasions . Authors
The greater is the circle of light, the greater is the boundary of the darkness by which it is confined. But, notwithstanding this, the more light get, the more thankful we ought to be, for by this means we have the greater range for satisfactory contemplation. time the bounds of light will be still farther extended; and from the infinity of the divine nature, and the divine works, we may promise ourselves an endless progress in our investigation them: a prospect truly sublime and glorious.
Know thyself! This is the source of all wisdom, said the great thinkers of the past, and the sentence was written in golden letters on the temple of the gods. To know himself, Linnæus declared to be the essential indisputable distinction of man above all other creatures. I know, indeed, in study nothing more worthy of free and thoughtful man than the study of himself. For if we look for the purpose of our existence, we cannot possibly find it outside ourselves. We are here for our own sake.
The phrase 'contrary to all expectations' rings through the story of the progress of human knowledge. It was 'contrary to all expectations' that the Earth was found to revolve around the sun, and not the other way round, and that a mould growing in one of Dr. Alexander Fleming's dishes was found to be capable of destroying bacteria. When in 1989 the spacecraft Voyager 2 got close enough to the planet Naptune to take detailed pictures of the surface, they were 'contrary to all expectations'.
But the idea of science and systematic knowledge is wanting to our whole instruction alike, and not only to that of our business class ... In nothing do England and the Continent at the present moment more strikingly differ than in the prominence which is now given to the idea of science there, and the neglect in which this idea still lies here; a neglect so great that we hardly even know the use of the word science in its strict sense, and only employ it in a secondary and incorrect sense.
If there be an order in which the human race has mastered its various kinds of knowledge, there will arise in every child an aptitude to acquire these kinds of knowledge in the same order. So that even were the order intrinsically indifferent, it would facilitate education to lead the individual mind through the steps traversed by the general mind. But the order is not intrinsically indifferent; and hence the fundamental reason why education should be a repetition of civilization in little.
I recently went to my staircase at Clare College, Cambridge and there were women there! There have been a lot of convincing studies recently about the loss of productivity in the Western male. It may be that entertainment culture now is so engaging that it keeps people satisfied. We didn't have that. Science was much more fun than listening to the radio. When you are 16 or 17 and in that inherently semi-lonely period when you are deciding whether to be an intellectual, many now don't bother.
The story is told of Lord Kelvin, a famous Scotch physicist of the last century, that after he had given a lecture on atoms and molecules, one of his students came to him with the question, "Professor, what is your idea of the structure of the atom." "What," said Kelvin, "The structure of the atom? Why, don't you know, the very word 'atom' means the thing that can't be cut. How then can it have a structure?" "That," remarked the facetious young man, "shows the disadvantage of knowing Greek."
Time is in itself [not] a difficulty, but a time-rate, assumed on very insufficient grounds, is used as a master-key, whether or not it fits, to unravel all difficulties. What if it were suggested that the brick-built Pyramid of Hawara had been laid brick by brick by a single workman? Given time, this would not be beyond the bounds of possibility. But Nature, like the Pharaohs, had greater forces at her command to do the work better and more expeditiously than is admitted by Uniformitarians.
Astronomy is so easy to love. ... Fairly or not, physics is associated with nuclear bombs and nuclear waste, chemistry with pesticides, biology with Frankenfood and designer-gene superbabies. But astronomers are like responsible ecotourists, squinting at the scenery through high-quality optical devices, taking nothing but images that may be computer-enhanced for public distribution, leaving nothing but a few Land Rover footprints on faraway Martian soil, and OK, OK, maybe the Land Rover, too.
Scientists themselves readily admit that they do not fully understand the consequences of our many-faceted assault upon the interwoven fabric of atmosphere, water, land and life in all its biological diversity. But things could also turn out to be worse than the current scientific best guess. In military affairs, policy has long been based on the dictum that we should be prepared for the worst case. Why should it be so different when the security is that of the planet and our long-term future?
It may be said of some very old places, as of some very old books, that they are destined to be forever new. The nearer we approach them, the more remote they seem: the more we study them, the more we have yet to learn. Time augments rather than diminishes their everlasting novelty; and to our descendants of a thousand years hence it may safely be predicted that they will be even more fascinating than to ourselves. This is true of many ancient lands, but of no place is it. so true as of Egypt.
Lately, however, on abandoning the brindled and grey mosquitos and commencing similar work on a new, brown species, of which I have as yet obtained very few individuals, I succeeded in finding in two of them certain remarkable and suspicious cells containing pigment identical in appearance to that of the parasite of malaria. As these cells appear to me to be very worthy of attention ... I think it would be advisable to place on record a brief description both of the cells and of the mosquitos.
Science is not a system of certain, or -established, statements; nor is it a system which steadily advances towards a state of finality... And our guesses are guided by the unscientific, the metaphysical (though biologically explicable) faith in laws, in regularities which we can uncover-discover. Like Bacon, we might describe our own contemporary science-'the method of reasoning which men now ordinarily apply to nature'-as consisting of 'anticipations, rash and premature' and as 'prejudices'.
All living organisms are but leaves on the same tree of life. The various functions of plants and animals and their specialized organs are manifestations of the same living matter. This adapts itself to different jobs and circumstances, but operates on the same basic principles. Muscle contraction is only one of these adaptations. In principle it would not matter whether we studied nerve, kidney or muscle to understand the basic principles of life. In practice, however, it matters a great deal.
Next came the Patent laws. These began in England in 1624; and, in this country, with the adoption of our constitution. Before then [these?], any man might instantly use what another had invented; so that the inventor had no special advantage from his own invention. The patent system changed this; secured to the inventor, for a limited time, the exclusive use of his invention; and thereby added the fuel of interest to the fire of genius, in the discovery and production of new and useful things.
The Christians who engaged in infamous persecutions and shameful inquisitions were not evil men but misguided men. The churchmen who felt they had an edict from God to withstand the progress of science, whether in the form of a Copernican revolution or a Darwinian theory of natural selection, were not mischievous men but misinformed men. And so Christ's words from the cross are written in sharp-edged terms across some of the most inexpressible tragedies of history: 'They know not what they do'.
No mathematician should ever allow him to forget that mathematics, more than any other art or science, is a young man's game. ... Galois died at twenty-one, Abel at twenty-seven, Ramanujan at thirty-three, Riemann at forty. There have been men who have done great work later; ... [but] I do not know of a single instance of a major mathematical advance initiated by a man past fifty. ... A mathematician may still be competent enough at sixty, but it is useless to expect him to have original ideas.
The psychiatric interviewer is supposed to be doing three things: considering what the patient could mean by what he says; considering how he himself can best phrase what he wishes to communicate to the patient; and, at the same time, observing the general pattern of the events being communicated. In addition to that, to make notes which will be of more than evocative value, or come anywhere near being a verbatim record of what is said, in my opinion is beyond the capacity of most human beings.
But the World being once fram'd, and the course of Nature establish'd, the Naturalist, (except in some few cases, where God, or Incorporeal Agents interpose), has recourse to the first Cause but for its general and ordinary Support and Influence, whereby it preserves Matter and Motion from Annihilation or Desition; and in explicating particular phenomena, considers onely the Size, Shape, Motion, (or want of it) Texture, and the resulting Qualities and Attributes of the small particles of Matter.
Science gains from it [the pendulum] more than one can expect. With its huge dimensions, the apparatus presents qualities that one would try in vain to communicate by constructing it on a small [scale], no matter how carefully. Already the regularity of its motion promises the most conclusive results. One collects numbers that, compared with the predictions of theory, permit one to appreciate how far the true pendulum approximates or differs from the abstract system called 'the simple pendulum'.
When I began my physical studies [in Munich in 1874] and sought advice from my venerable teacher Philipp von Jolly...he portrayed to me physics as a highly developed, almost fully matured science...Possibly in one or another nook there would perhaps be a dust particle or a small bubble to be examined and classified, but the system as a whole stood there fairly secured, and theoretical physics approached visibly that degree of perfection which, for example, geometry has had already for centuries.
Asian Homo erectus died without issue and does not enter our immediate ancestry (for we evolved from African populations); Neanderthal people were collateral cousins, perhaps already living in Europe while we emerged in Africa... In other words, we are an improbable and fragile entity, fortunately successful after precarious beginnings as a small population in Africa, not the predictable end result of a global tendency. We are a thing, an item of history, not an embodiment of general principles.
Malthus argued a century and a half ago that man, by using up all his available resources, would forever press on the limits of subsistence, thus condemning humanity to an indefinite future of misery and poverty. We can now begin to hope and, I believe, know that Malthus was expressing not a law of nature, but merely the limitation then of scientific and social wisdom. The truth or falsity of his prediction will depend now, with the tools we have, on our own actions, now and in the years to come.
Pathology, probably more than any other branch of science, suffers from heroes and hero-worship. Rudolf Virchow has been its archangel and William Welch its John the Baptist, while Paracelsus and Cohnheim have been relegated to the roles of Lucifer and Beelzebub. ... Actually, there are no heroes in Pathology-all of the great thoughts permitting advance have been borrowed from other fields, and the renaissance of pathology stems not from pathology itself but from the philosophers Kant and Goethe.
Invention is an Heroic thing, and plac'd above the reach of a low, and vulgar Genius. It requires an active, a bold, a nimble, a restless mind: a thousand difficulties must be contemn'd with which a mean heart would be broken: many attempts must be made to no purpose: much Treasure must sometimes be scatter'd without any return: much violence, and vigour of thoughts must attend it: some irregularities, and excesses must be granted it, that would hardly be pardon'd by the severe Rules of Prudence.
The beginning of civilisation is the discovery of some useful arts, by which men acquire property, comforts, or luxuries. The necessity or desire of preserving them leads to laws and social institutions. The discovery of peculiar arts gives superiority to particular nations ... to subjugate other nations, who learn their arts, and ultimately adopt their manners;- so that in reality the origin as well as the progress and improvement of civil society is founded in mechanical and chemical inventions.
The alchemists of past centuries tried hard to make the elixir of life: ... Those efforts were in vain; it is not in our power to obtain the experiences and the views of the future by prolonging our lives forward in this direction. However, it is well possible in a certain sense to prolong our lives backwards by acquiring the experiences of those who existed before us and by learning to know their views as well as if we were their contemporaries. The means for doing this is also an elixir of life.
To be worthy of the name, an experimenter must be at once theorist and practitioner. While he must completely master the art of establishing experimental facts, which are the materials of science, he must also clearly understand the scientific principles which guide his reasoning through the varied experimental study of natural phenomena. We cannot separate these two things: head and hand. An able hand, without a head to direct it, is a blind tool; the head is powerless without its executive hand.
I have been scientifically studying the traits and dispositions of the "lower animals" (so-called,) and contrasting them with the traits and dispositions of man. I find the result profoundly humiliating to me. For it obliges me to renounce my allegiance to the Darwinian theory of the Ascent of Man from the Lower Animals; since it now seems plain to me that that theory ought to be vacated in favor of a new and truer one, this new and truer one to be named the Descent of Man from the Higher Animals.
I have not yet lost a feeling of wonder, and of delight, that this delicate motion should reside in all the ordinary things around us, revealing itself only to him who looks for it. I remember, in the winter of our first experiments, just seven years ago, looking on snow with new eyes. There the snow lay around my doorstep - great heaps of protons quietly precessing in the earth’s magnetic field. To see the world for a moment as something rich and strange is the private reward of many a discovery.
It is notorious that the same discovery is frequently made simultaneously and quite independently, by different persons. Thus, to speak of only a few cases in late years, the discoveries of photography, of electric telegraphy, and of the planet Neptune through theoretical calculations, have all their rival claimants. It would seem, that discoveries are usually made when the time is ripe for them - that is to say, when the ideas from which they naturally flow are fermenting in the minds of many men.
Shall an invention be patented or donated to the public freely? I have known some well-meaning scientific men ... to look askance at the patenting of inventions, as if it were a rather selfish and ungracious act, essentially unworthy. The answer is very simple. Publish an invention freely, and it will almost surely die from lack of interest in its development. It will not be developed and the world will not be benefited. Patent it, and if valuable, it will be taken up and developed into a business.
After Gibbs, one the most distinguished [American scientists] was Langley, of the Smithsonian. ... He had the physicist's heinous fault of professing to know nothing between flashes of intense perception. ... Rigidly denying himself the amusement of philosophy, which consists chiefly in suggesting unintelligible answers to insoluble problems, and liked to wander past them in a courteous temper, even bowing to them distantly as though recognizing their existence, while doubting their respectibility.
In point of fact, no conclusive disproof of a theory can ever be produced; for it is always possible to say that the experimental results are not reliable or that the discrepancies which are asserted to exist between the experimental results and the theory are only apparent and that they will disappear with the advance of our understanding. If you insist on strict proof (or strict disproof) in the empirical sciences, you will never benefit from experience, and never learn from it how wrong you are.
The foundations of population genetics were laid chiefly by mathematical deduction from basic premises contained in the works of Mendel and Morgan and their followers. Haldane, Wright, and Fisher are the pioneers of population genetics whose main research equipment was paper and ink rather than microscopes, experimental fields, Drosophila bottles, or mouse cages. Theirs is theoretical biology at its best, and it has provided a guiding light for rigorous quantitative experimentation and observation.
The hybridoma technology was a by-product of basic research. Its success in practical applications is to a large extent the result of unexpected and unpredictable properties of the method. It thus represents another clear-cut example of the enormous practical impact of an investment in research which might not have been considered commercially worthwhile, or of immediate medical relevance. It resulted from esoteric speculations, for curiosity's sake, only motivated by a desire to understand nature.
The fundamental biological variant is DNA. That is why Mendel's definition of the gene as the unvarying bearer of hereditary traits, its chemical identification by Avery (confirmed by Hershey), and the elucidation by Watson and Crick of the structural basis of its replicative invariance, are without any doubt the most important discoveries ever made in biology. To this must be added the theory of natural selection, whose certainty and full significance were established only by those later theories.
Faced with a new mutation in an organism, or a fundamental change in its living conditions, the biologist is frequently in no position whatever to predict its future prospects. He has to wait and see. For instance, the hairy mammoth seems to have been an admirable animal, intelligent and well-accoutered. Now that it is extinct, we try to understand why it failed. I doubt that any biologist thinks he could have predicted that failure. Fitness and survival are by nature estimates of past performance.
I have a true aversion to teaching. The perennial business of a professor of mathematics is only to teach the ABC of his science; most of the few pupils who go a step further, and usually to keep the metaphor, remain in the process of gathering information, become only Halbwisser [one who has superficial knowledge of the subject], for the rarer talents do not want to have themselves educated by lecture courses, but train themselves. And with this thankless work the professor loses his precious time.
Somewhere in the arrangement of this world there seems to be a great concern about giving us delight, which shows that, in the universe, over and above the meaning of matter and forces, there is a message conveyed through the magic touch of personality. ... Is it merely because the rose is round and pink that it gives me more satisfaction than the gold which could buy me the necessities of life, or any number of slaves. ... Somehow we feel that through a rose the language of love reached our hearts.
The ordinary patient goes to his doctor because he is in pain or some other discomfort and wants to be comfortable again; he is not in pursuit of the ideal of health in any direct sense. The doctor on the other hand wants to discover the pathological condition and control it if he can. The two are thus to some degree at cross purposes from the first, and unless the affair is brought to an early and happy conclusion this diversion of aims is likely to become more and more serious as the case goes on.
Although human ingenuity may devise various inventions which, by the help of various instruments, answer to one and the same purpose, yet will it never discover any inventions more beautiful, more simple or more practical than those of nature, because in her inventions there is nothing lacking and nothing superfluous; and she makes use of no counterpoise when she constructs the limbs of animals in such a way as to correspond to the motion of their bodies, but she puts into them the soul of the body.
Had I been present at the Creation, I would have given some useful hints for the better ordering of the universe. Remarking on the complexity of Ptolemaic model of the universe after it was explained to him. Footnote: Carlyle says, in his History of Frederick the Great, book ii. chap. vii. that this saying of Alphonso about Ptolemy's astronomy, 'that it seemed a crank machine; that it was pity the Creator had not taken advice,' is still remembered by mankind, - this and no other of his many sayings.
[Microscopic] evidence cannot be presented ad populum. What is seen with the microscope depends not only upon the instrument and the rock-section, but also upon the brain behind the eye of the observer. Each of us looks at a section with the accumulated experience of his past study. Hence the veteran cannot make the novice see with his eyes; so that what carries conviction to the one may make no appeal to the other. This fact does not always seem to be sufficiently recognized by geologists at large.
Mathematics, rightly viewed, possesses not only truth, but supreme beauty a beauty cold and austere, like that of sculpture, without appeal to any part of our weaker nature, without the georgeous trappings of painting or music, yet sublimely pure, and capable of a stern perfection such as only the greatest art can show. The true spirit of delight, the exaltation, the sense of being more than Man, which is the touchstone of the highest excellence, is to be found in mathematics as surely as in poetry.
It appears that all that can be, is. The Creator's hand does not appear to have been opened in order to give existence to a certain determinate number of species, but it seems that it has thrown out all at once a world of relative and non-relative creatures, an infinity of harmonic and contrary combinations and a perpetuity of destructions and replacements. What idea of power is not given us by this spectacle! What feeling of respect for its Author is not inspired in us by this view of the universe!
Let us suppose that we have laid on the table... [a] piece of glass... and let us homologize this glass to a whole order of plants or birds. Let us hit this glass a blow in such a manner as but to crack it up. The sectors circumscribed by cracks following the first blow may here be understood to represent families. Continuing, we may crack the glass into genera, species and subspecies to the point of finally having the upper right hand corner a piece about 4 inches square representing a sub-species.
Your remarks upon chemical notation with the variety of systems which have arisen, &c., &c., had almost stirred me up to regret publicly that such hindrances to the progress of science should exist. I cannot help thinking it a most unfortunate thing that men who as experimentalists & philosophers are the most fitted to advance the general cause of science & knowledge should by promulgation of their own theoretical views under the form of nomenclature, notation, or scale, actually retard its progress.
One orbit, with a radius of 42,000 kilometers, has a period of exactly 24 hours. A body in such an orbit, if its plane coincided with that of the Earth's equator, would revolve with the Earth and would thus be stationary above the same spot on the planet. It would remain fixed in the sky of a whole hemisphere ... [to] provide coverage to half the globe, and for a world service three would be required, though more could be readily utilized. (1945) [Predidicting geosynchronous communication satellites]
Whatsoever accidents or qualities our senses make us think there be in the world, they are not there, but are seemings and apparitions only. The things that really are in the world without us, are those motions by which these seemings are caused. And this is the great deception of sense, which also is by sense to be corrected. For as sense telleth me, when I see directly, that the colour seemeth to be in the object; so also sense telleth me, when I see by reflection, that colour is not in the object.