It is sometimes asserted that a surgical operation is or should be a work of art ... fit to rank with those of the painter or sculptor. ... That proposition does not admit of discussion. It is a product of the intellectual innocence which I think we surgeons may fairly claim to possess, and which is happily not inconsistent with a quite adequate worldly wisdom.

Our belief is not a belief. Our principles are not a faith. We do not rely soley upon science and reason, because these are necessary rather than sufficient factors, but we distrust anything that contradicts science or outrages reason. We may differ on many things, but what we respect is free inquiry, openmindedness, and the pursuit of ideas for their own sake.

It is ... a sign of the times-though our brothers of physics and chemistry may smile to hear me say so-that biology is now a science in which theories can be devised: theories which lead to predictions and predictions which sometimes turn out to be correct. These facts confirm me in a belief I hold most passionately-that biology is the heir of all the sciences.

When even the brightest mind in our world has been trained up from childhood in a superstition of any kind, it will never be possible for that mind, in its maturity, to examine sincerely, dispassionately, and conscientiously any evidence or any circumstance which shall seem to cast a doubt upon the validity of that superstition. I doubt if I could do it myself.

Armed with all the powers, enjoying all the wealth they owe to science, our societies are still trying to practice and to teach systems of values already destroyed at the roots by that very science. Man knows at last that he is alone in the indifferent immensity of the universe, whence which he has emerged by chance. His duty, like his fate, is written nowhere.

Give me a dozen healthy infants, well-formed, and my own specified world to bring them up and I'll guarantee to take any one at random and train him to become any type of specialist I might select-doctor, lawyer, merchant-chief, and yes, even beggar man and thief, regardless of his talents, penchants, tendencies, abilities, vocations, and race of his ancestors.

I doubt that Fleming could have obtained a grant for the discovery of penicillin on that basis [a requirement for highly detailed research plans] because he could not have said, 'I propose to have an accident in a culture so that it will be spoiled by a mould falling on it, and I propose to recognize the possibility of extracting an antibiotic from this mould.'

Ostwald was a great protagonist and an inspiring teacher. He had the gift of saying the right thing in the right way. When we consider the development of chemistry as a whole, Ostwald's name like Abou ben Adhem's leads all the rest ... Ostwald was absolutely the right man in the right place. He was loved and followed by more people than any chemist of our time.

What is the shape of space? Is it flat, or is it bent? Is it nicely laid out, or is it warped and shrunken? Is it finite, or is it infinite? Which of the following does space resemble more: (a) a sheet of paper, (b) an endless desert, (c) a soap bubble, (d) a doughnut, (e) an Escher drawing, (f) an ice cream cone, (g) the branches of a tree, or (h) a human body?

We cannot step aside and say that we have achieved our goal by inventing a new drug or a new way by which to treat presently incurable diseases, a new way to help those who suffer from malnutrition, or the creation of ideal balanced diets on a worldwide scale. We cannot rest till the way has been found, with our help, to bring our finest achievement to everyone.

The chief instrument of American statistics is the census, which should accomplish a two-fold object. It should serve the country by making a full and accurate exhibit of the elements of national life and strength, and it should serve the science of statistics by so exhibiting general results that they may be compared with similar data obtained by other nations.

I have read various articles on the fourth dimension, the relativity theory of Einstein, and other psychological speculation on the constitution of the universe; and after reading them I feel as Senator Brandegee felt after a celebrated dinner in Washington. "I feel," he said, "as if I had been wandering with Alice in Wonderland and had tea with the Mad Hatter."

My work on prime gaps lead to lots of media coverage, some good, some bad, some ugly, and some merely ridiculous. For example, a reporter of our university newspaper, who admitted that he is still learning English, wrote that "Prof. Goldston solved one of the most controversial problems in the prime number theory last month with support from his Turkish partner."

The day when the scientist, no matter how devoted, may make significant progress alone and without material help is past. This fact is most self-evident in our work. Instead of an attic with a few test tubes, bits of wire and odds and ends, the attack on the atomic nucleus has required the development and construction of great instruments on an engineering scale.

[This] may prove to be the beginning of some embracing generalization, which will throw light, not only on radioactive processes, but on elements in general and the Periodic Law.... Chemical homogeneity is no longer a guarantee that any supposed element is not a mixture of several of different atomic weights, or that any atomic weight is not merely a mean number.

I am among those who think that science has great beauty. A scientist in his laboratory is not only a technician: he is also a child placed before natural phenomena which impress him like a fairy tale. We should not allow it to be believed that all scientific progress can be reduced to mechanisms, machines, gearings, even though such machinery has its own beauty.

Considered as a mere question of physics, (and keeping all moral considerations entirely out of sight,) the appearance of man is a geological phenomenon of vast importance, indirectly modifying the whole surface of the earth, breaking in upon any supposition of zoological continuity, and utterly unaccounted for by what we have any right to call the laws of nature.

Any one who has studied the history of science knows that almost every great step therein has been made by the "anticipation of Nature," that is, by the invention of hypotheses, which, though verifiable, often had very little foundation to start with; and, not unfrequently, in spite of a long career of usefulness, turned out to be wholly erroneous in the long run.

[The] first postulate of the Principle of Uniformity, namely, that the laws of nature are invariant with time, is not peculiar to that principle or to geology, but is a common denominator of all science. In fact, instead of being an assumption or an ad hoc hypothesis, it is simply a succinct summation of the totality of all experimental and observational evidence.

[The Royal Society] is quite simply the voice of science in Britain. It is intellectually rigorous, not afraid to be outspoken on controversial issues such as climate change, but it is not aggressively secular either, insisting on a single view of the world. In fact, there are plenty of eminent scientists - Robert Winston, for instance - who are also men of faith.

To most ... of us, Russia was as mysterious and remote as the other side of the moon and not much more productive when it came to really new ideas or inventions. A common joke of the time [mid 1940s] said that the Russians could not surreptitiously introduce nuclear bombs in suitcases into the United States because they had not yet been able to perfect a suitcase.

I am convinced that this is the only means of advancing science, of clearing the mind from a confused heap of contradictory observations, that do but perplex and puzzle the Student, when he compares them, or misguide him if he gives himself up to their authority; but bringing them under one general head, can alone give rest and satisfaction to an inquisitive mind.

Amid all the revolutions of the globe, the economy of Nature has been uniform, ... and her laws are the only things that have resisted the general movement. The rivers and the rocks, the seas and the continents, have been changed in all their parts; but the laws which direct those changes, and the rules to which they are subject, have remained invariably the same.

[At the end of the story, its main character, Tom] is now a great man of science, and can plan railroads, and steam-engines, and electric telegraphs, and rifled guns, and so forth; and knows everything about everything, except why a hen's egg don't turn into a crocodile, and two or three other little things that no one will know till the coming of the Cocqcigrues.

Insofar as he makes use of his healthy senses, man himself is the best and most exact scientific instrument possible. The greatest misfortune of modern physics is that its experiments have been set apart from man, as it were, physics refuses to recognize nature in anything not shown by artificial instruments, and even uses this as a measure of its accomplishments.

It is told of Faraday that he refused to be called a physicist; he very much disliked the new name as being too special and particular and insisted on the old one, philosopher, in all its spacious generality: we may suppose that this was his way of saying that he had not over-ridden the limiting conditions of class only to submit to the limitation of a profession.

I am not very sceptical, — a frame of mind which I believe to be injurious to the progress of science. A good deal of scepticism in a scientific man is advisable to avoid much loss of time, but I have met with not a few men, who, I feel sure, have often thus been deterred from experiment or observations, which would have proved directly or indirectly serviceable .

If the world were to end tomorrow and we could choose to save only one thing as the explanation and memorial to who we were, then we couldn't do better than the Natural History Museum, although it wouldn't contain a single human. The systematic Linnean order, the vast inquisitiveness and range of collated knowledge and beauty would tell all that is the best of us.

In a sense Shapley's telling me that space was transparent, which I shouldn't have believed, illustrates a fundamental problem in science, believing what people tell you. Go and find it out for yourself. That same error has persisted in my life and in many other people's. Authorities are not always authorities on everything; they often cling to their own mistakes.

Cuvier had even in his address & manner the character of a superior Man, much general power & eloquence in conversation & great variety of information on scientific as well as popular subjects. I should say of him that he is the most distinguished man of talents I have ever known on the continent: but I doubt if He be entitled to the appellation of a Man of Genius.

About thirty years ago there was much talk that geologists ought only to observe and not theorise; and I well remember some one saying that at this rate a man might as well go into a gravel-pit and count the pebbles and describe the colours. How odd it is that anyone should not see that all observation must be for or against some view if it is to be of any service!

On the most usual assumption, the universe is homogeneous on the large scale, i.e. down to regions containing each an appreciable number of nebulae. The homogeneity assumption may then be put in the form: An observer situated in a nebula and moving with the nebula will observe the same properties of the universe as any other similarly situated observer at any time.

I have lived much of my life among molecules. They are good company. I tell my students to try to know molecules, so well that when they have some question involving molecules, they can ask themselves, What would I do if I were that molecule? I tell them, Try to feel like a molecule; and if you work hard, who knows? Some day you may get to feel like a big molecule!

If physicists could not quote in the text, they would not feel that much was lost with respect to advancement of knowledge of the natural world. If historians could not quote, they would deem it a disastrous impediment to the communication of knowledge about the past. A luxury for physicists, quotation is a necessity for historians, indispensable to historiography.

I have flown twice over Mount St. Helens out on our West Coast. I'm not a scientist and I don't know the figures, but I have a suspicion that that one little mountain has probably released more sulfur dioxide into the atmosphere of the world than has been released in the last ten years of automobile driving or things of that kind that people are so concerned about.

The question now at issue, whether the living species are connected with the extinct by a common bond of descent, will best be cleared up by devoting ourselves to the study of the actual state of the living world, and to those monuments of the past in which the relics of the animate creation of former ages are best preserved and least mutilated by the hand of time.

Common sense is science exactly in so far as it fulfills the ideal of common sense; that is, sees facts as they are, or at any rate, without the distortion of prejudice, and reasons from them in accordance with the dictates of sound judgment. And science is simply common sense at its best, that is, rigidly accurate in observation, and merciless to fallacy in logic.

In less than eight years "The Origin of Species" has produced conviction in the minds of a majority of the most eminent living men of science. New facts, new problems, new difficulties as they arise are accepted, solved, or removed by this theory; and its principles are illustrated by the progress and conclusions of every well established branch of human knowledge.

We are having wool pulled over our eyes if we let ourselves be convinced that scientists, taken as a group, are anything special in the way of brains. They are very ordinary professional men, and all they know is their own trade, just like all other professional men. There are some geniuses among them, just as there are mental giants in any other field of endeavor.

I understood that you would take the Human Race in the concrete, have exploded the absurd notion of Pope's Essay on Man, [Erasmus] Darwin, and all the countless Believers-even (strange to say) among Xtians-of Man's having progressed from an Ouran Outang state-so contrary to all History, to all Religion, nay, to all Possibility-to have affirmed a Fall in some sense.

From the point of view of the pure morphologist the recapitulation theory is an instrument of research enabling him to reconstruct probable lines of descent; from the standpoint of the student of development and heredity the fact of recapitulation is a difficult problem whose solution would perhaps give the key to a true understanding of the real nature of heredity.

[The] weakness of biological balance studies has aptly been illustrated by comparison with the working of a slot machine. A penny brings forth one package of chewing gum; two pennies bring forth two. Interpreted according to the reasoning of balance physiology, the first observation is an indication of the conversion of copper into gum; the second constitutes proof.

The recurrence of a phenomenon like Edison is not very likely. The profound change of conditions and the ever increasing necessity of theoretical training would seem to make it impossible. He will occupy a unique and exalted position in the history of his native land, which might well be proud of his great genius and undying achievements in the interest of humanity.

Freud expressed the opinion-not quite in earnest, though, it seeemed to me-that philosophy was the most decent form of sublimation of repressed sexuality, nothing more. In response I put the question, 'What then is science, particularly psychoanalytic psychology?' Whereup on he, visible a bit surprised, answered evasively: 'At least psychology has a social purpose.'

Pauling was shocked by the freedom with which the X-ray crystallographers of the time, including particularly Astbury, played with the intimate chemical structure of their models. They seemed to think that if the atoms were arranged in the right order and about the right distance apart, that was all that mattered, that no further restrictions need to be put on them.

Science is rooted in the will to truth. With the will to truth it stands or falls. Lower the standard even slightly and science becomes diseased at the core. Not only science, but man. The will to truth, pure and unadulterated, is among the essential conditions of his existence; if the standard is compromised he easily becomes a kind of tragic caricature of himself.

Mathematics is not arithmetic. Though mathematics may have arisen from the practices of counting and measuring it really deals with logical reasoning in which theorems-general and specific statements-can be deduced from the starting assumptions. It is, perhaps, the purest and most rigorous of intellectual activities, and is often thought of as queen of the sciences.

Let people who have to observe sickness and death look back and try to register in their observation the appearances which have preceded relapse, attack or death, and not assert that there were none, or that there were not the right ones. A want of the habit of observing conditions and an inveterate habit of taking averages are each of them often equally misleading.

Yet man does recognise himself [as an animal]. But I ask you and the whole world for a generic differentia between man and ape which conforms to the principles of natural history, I certainly know of none... If I were to call man ape or vice versa, I should bring down all the theologians on my head. But perhaps I should still do it according to the rules of science.

To turn Karl [Popper]'s view on its head, it is precisely the abandonment of critical discourse that marks the transition of science. Once a field has made the transition, critical discourse recurs only at moments of crisis when the bases of the field are again in jeopardy. Only when they must choose between competing theories do scientists behave like philosophers.

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