I always wanted to be a scientist, I always thought I'd be a scientist, that was the narrative I was carrying around. I worked in a neuroscience lab as an undergraduate and then after, almost five years in total, but I realized I just wasn't good at science. I didn't have the discipline for it.

Although such research [into the paranormal] has yet to produce anything in the way of a repeatable controlled experiment, its practitioners argue that its revolutionary potentialities justify its continuation. My own feeling is that after a century of total failure it has become a bloody bore.

The method of science depends on our attempts to describe the world with simple theories: theories that are complex may become untestable, even if they happen to be true. Science may be described as the art of systematic over-simplification-the art of discerning what we may with advantage omit.

... finding that in [the Moon] there is a provision of light and heat; also in appearance, a soil proper for habitation fully as good as ours, if not perhaps better who can say that it is not extremely probable, nay beyond doubt, that there must be inhabitants on the Moon of some kind or other?

The aim of science is to seek the simplest explanation of complex facts. We are apt to fall into the error of thinking that the facts are simple because simplicity is the goal of our quest. The guiding motto in the life of every natural philosopher should be ``Seek simplicity and distrust it.''

I am going to tell you what nature behaves like. If you will simply admit that maybe she does behave like this, you will find her a delightful, entrancing thing. Do not keep saying to yourself, if you can possibly avoid it, 'But how can it be like that?' ...Nobody knows how it can be like that.

There are no physicists in the hottest parts of hell, because the existence of a hottest part implies a temperature difference, and any marginally competent physicist would immediately use this to run a heat engine and make some other part of hell comfortably cool. This is obviously impossible.

I decided that life rationally considered seemed pointless and futile, but it is still interesting in a variety of ways, including the study of science. So why not carry on, following the path of scientific hedonism? Besides, I did not have the courage for the more rational procedure of suicide.

Thus the great drama of universal life is perpetually sustained; and though the individual actors undergo continual change, the same parts are ever filled by another and another generation; renewing the face of the earth, and the bosom of the deep, with endless successions of life and happiness.

He will also find that the high and independent spirit, which usually dwells in the breast of those who are deeply versed in scientific pursuits, is ill adapted for administrative appointments; and that even if successful, he must hear many things he disapproves, and raise no voice against them.

Until we consider animal life to be worthy of the consideration and reverence we bestow upon old books and pictures and historic monuments, there will always be the animal refugee living a precarious life on the edge of extermination, dependent for existence on the charity of a few human beings.

Widespread intellectual and moral docility may be convenient for leaders in the short term, but it is suicidal for nations in the long term. One of the criteria for national leadership should therefore be a talent for understanding, encouraging, and making constructive use of vigorous criticism.

Science now finds itself in paradoxical strife with society: admired but mistrusted; offering hope for the future but creating ambiguous choice; richly supported yet unable to fulfill all its promise; boasting remarkable advances but criticized for not serving more directly the goals of society.

Each species may have had its origin in a single pair, or individual, where an individual was sufficient, and species may have been created in succession at such times and in such places as to enable them to multiply and endure for an appointed period, and occupy an appointed space on the globe.

There is always more in one of Ramanujan's formulae than meets the eye, as anyone who sets to work to verify those which look the easiest will soon discover. In some the interest lies very deep, in others comparatively near the surface; but there is not one which is not curious and entertaining.

I think of it as a good opportunity to let, in particular, school kids know that this job and other interesting jobs in science and engineering are open to anyone who works hard in school and gets a good education and studies math and science. And that it's not just for a select group of people.

Please don't make the mistake of thinking that 'Oryx and Crake' is anti-science. Science is a way of knowing, and a tool. Like all ways of knowing and tools, it can be turned to bad uses. And it can be bought and sold, and it often is. But it is not in itself bad. Like electricity, it's neutral.

Personally I think there is no doubt that sub-atomic energy is available all around us, and that one day man will release and control its almost infinite power. We cannot prevent him from doing so and can only hope that he will not use it exclusively in blowing up his next door neighbour. (1936)

I came to realize that exaggerated concern about what others are doing can be foolish. It can paralyze effort, and stifle a good idea. One finds that in the history of science, almost every problem has been worked out by someone else. This should not discourage anyone from pursuing his own path.

I belonged to a small minority of boys who were lacking in physical strength and athletic prowess. ... We found our refuge in science. ... We learned that science is a revenge of victims against oppressors, that science is a territory of freedom and friendship in the midst of tyranny and hatred.

Science is composed of laws which were originally based on a small, carefully selected set of observations, often not very accurately measured originally; but the laws have later been found to apply over much wider ranges of observations and much more accurately than the original data justified.

The theory of the method of knowing which is advanced in these pages may be termed pragmatic. ... Only that which has been organized into our disposition so as to enable us to adapt the environment to our needs and adapt our aims and desires to the situation in which we live is really knowledge.

Classification is now a pejorative statement. You know, these classifiers look like "dumb fools." I'm a classifier. But I'd like to use a word that includes more than what people consider is encompassed by classification. It is more than that, and it's something which can be called phenomenology.

Probably if half a kilogram [of radium] were in a bottle on that table it would kill us all. It would almost certainly destroy our sight and burn our skins to such an extent that we could not survive. The smallest bit placed on one's arm would produce a blister which it would need months to heal.

...the life of the planet began the long, slow process of modulating and regulating the physical conditions of the planet. The oxygen in today's atmosphere is almost entirely the result of photosynthetic living, which had its start with the appearance of blue-green algae among the microorganisms.

I have been asked whether I would agree that the tragedy of the scientist is that he is able to bring about great advances in our knowledge, which mankind may then proceed to use for purposes of destruction. My answer is that this is not the tragedy of the scientist; it is the tragedy of mankind.

But he who has been earnest in the love of knowledge and of true wisdom, and has exercised his intellect more than any other part of him, must have thoughts immortal and divine. If he attain truth, and in so far as human nature is capable of sharing in immortality, he must altogether be immortal.

Next you'd see a raft sliding by, away off yonder, and maybe a galoot on it chopping. . . you'd see the ax flash and come down-you don't hear nothing; you see the ax go up again, and by the time it's above the man's head then you hear the k'chunk!-it had took all that time to come over the water.

I went to the trash pile at Tuskegee Institute and started my laboratory with bottles, old fruit jars and any other thing I found I could use. ... [The early efforts were] worked out almost wholly on top of my flat topped writing desk and with teacups, glasses, bottles and reagents I made myself.

The existence of a first cause of the universe is a necessity of thought ... Amid the mysteries which become more mysterious the more they are thought about, there will remain the one absolute certainty that we are over in the presence of an Infinite, Eternal Energy from which all things proceed.

All knowledge resolves itself into probability. ... In every judgment, which we can form concerning probability, as well as concerning knowledge, we ought always to correct the first judgment deriv'd from the nature of the object, by another judgment, deriv'd from the nature of the understanding.

The partitions of knowledge are not like several lines that meet in one angle, and so touch not in a point; but are like branches of a tree, that meet in a stem, which hath a dimension and quantity of entireness and continuance, before it come to discontinue and break itself into arms and boughs.

To inquisitive minds like yours and mine the reflection that the quantity of human knowledge bears no proportion to the quantity of human ignorance must be in one view rather pleasing, viz., that though we are to live forever we may be continually amused and delighted with learning something new.

I have accumulated a wealth of knowledge in innumerable spheres and enjoyed it as an always ready instrument for exercising the mind and penetrating further and further. Best of all, mine has been a life of loving and being loved. What a tragedy that all this will disappear with the used-up body!

No engineer can go upon a new work and not find something peculiar, that will demand his careful reflection, and the deliberate consideration of any advice that he may receive; and nothing so fully reveals his incapacity as a pretentious assumption of knowledge, claiming to understand everything.

There are problems to whose solution I would attach an infinitely greater importance than to those of mathematics, for example touching ethics, or our relation to God, or concerning our destiny and our future; but their solution lies wholly beyond us and completely outside the province of science.

Economics is not an exact science. It's a combination of an art and elements of science. And that's almost the first and last lesson to be learned about economics: that in my judgment, we are not converging toward exactitude, but we're improving our data bases and our ways of reasoning about them.

You can't really discover the most interesting conflicts and problems in a subject until you've tried to write about them. At that point, one discovers discontinuities in the data, perhaps, or in one's own thinking; then the act of writing forces you to work harder to resolve these contradictions.

We may discover resources on the moon or Mars that will boggle the imagination, that will test our limits to dream. And the fascination generated by further exploration will inspire our young people to study math, and science, and engineering and create a new generation of innovators and pioneers.

Mathematics is the most exact science, and its conclusions are capable of absolute proof. But this is so only because mathematics does not attempt to draw absolute conclusions. All mathematical truths are relative, conditional. In E. T. Bell Men of Mathematics, New York: Simona and Schuster, 1937.

Nature uncovers the inner secrets of nature in two ways: one by the force of bodies operating outside it; the other by the very movements of its innards. The external actions are strong winds, rains, river currents, sea waves, ice, forest fires, floods; there is only one internal force-earthquake.

It is with our entire past ... that we desire, will and act ... from this survival of the past it follows that consciousness cannot go through the same state twice. The circumstances may still be the same, but they will act no longer on the same person ... that is why our duration is irreversible.

The theory of evolution by natural selection is an ecological theory-founded on ecological observation by perhaps the greatest of all ecologists. It has been adopted by and brought up by the science of genetics, and ecologists, being modest people, are apt to forget their distinguished parenthood.

Select such subjects that your pupils cannot walk out without seeing them. Train your pupils to be observers, and have them provided with the specimens about which you speak. If you can find nothing better, take a house-fly or a cricket, and let each one hold a specimen and examine it as you talk.

I looked for it [heavy hydrogen, deuterium] because I thought it should exist. I didn't know it would have industrial applications or be the basic for the most powerful weapon ever known [the nuclear bomb] ... I thought maybe my discovery might have the practical value of, say, neon in neon signs.

We think of Euclid as of fine ice; we admire Newton as we admire the peak of Teneriffe. Even the intensest labors, the most remote triumphs of the abstract intellect, seem to carry us into a region different from our own-to be in a terra incognita of pure reasoning, to cast a chill on human glory.

Science is not the affirmation of a set of beliefs but a process of inquiry aimed at building a testable body of knowledge constantly open to rejection or confirmation. In science, knowledge is fluid and certainty fleeting. That is at the heart of its limitations. It is also its greatest strength.

Whether statistics be an art or a science... or a scientific art, we concern ourselves little. It is the basis of social and political dynamics, and affords the only secure ground on which the truth or falsehood of the theories and hypotheses of that complicated science can be brought to the test.

When you enter a grove peopled with ancient trees, higher than the ordinary, and shutting out the sky with their thickly inter-twined branches, do not the stately shadows of the wood, the stillness of the place, and the awful gloom of this doomed cavern then strike you with the presence of a deity?

I described to my patent lawyer our new algorithm-that I was hoping to patent- about detecting clustering, that involved three probabilities α , β, γ that add-up to 1, and mentioned that it is like "a three-sided coin". A few days later he came up with a patent application for a "three-sided-coin".

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