Toby Tyrrell unravels the various formulations of Gaia and explains how recent scientific developments bring the hypothesis into question. His criticisms are insightful, profound, and convincing, but fair. On Gaia is wonderfully informative and a pleasure to read.

The greatest secret for eliminating the infirmity complex, which is another term for deep and profound self-doubt, is to fill your mind to overflowing faith. Develop a tremendous faith in God and that will give you a humble yet soundly realistic faith in yourself.

That the primary effect of gene mutation may be as simple as the substitution of a single amino acid by another and may lead to profound secondary changes in protein structure and properties has recently been strongly indicated by the work of Ingram on hemoglobin.

I would like to believe that the discovery of even a single fossil bacteria on Mars would teach us what we ought to know all along, and that is what binds us here on earth - all the diverse peoples here - is really much more profound than what seems to separate us.

Living in France while the Falklands War was going on, I felt a profound sense of shame and betrayal, just as I did by the war in Iraq. People have asked why I don't talk about that directly in my plays. Well, politics needs to be articulated in many different ways.

For us, the death of Osama bin Laden is a time of profound reflection. With his death, we remember and mourn all the lives lost on September 11. We remember and mourn all the lives lost in Iraq, Afghanistan, Pakistan. We remember and mourn the death of our soldiers.

You talk about a hateful bunch of people. They have this hate list. Charles Murray. He has been victimized with riots on college campus because he is depicted as a profound hater on the Southern Poverty Law Center website and the left treats that place like a Bible.

Performing is a profound experience, at least for me. It's not as if I sit down and play 'Fire and Rain' by myself, just to hear it again. But to offer it up... the energy that it somehow summons live takes me right back, and I do get a reconnection to the emotions.

If you're sixty-something, pushing 70, the chances of you getting a tremendously fascinating part in the movies are very low, as to be almost negligible, or even in television. But in the theatre, there are still things to do, very interesting, very profound things.

This [philanthropy] work is even more fascinating. It requires us to think harder about how we build partnerships, who we get behind. And yet we get to see progress that in some ways is even more profound than the great advances that digital technology has provided.

During the New Deal, liberals recognized that the ballot box and elected branches are generally the appropriate engines of social reform, and liberals used both to spectacular effect - instituting profound social changes that remain deeply ingrained in society today.

My role with the Pleiadians has been a profound journey of 24 years. Prior to meeting them, I had not believed in space ships or aliens, but I turned a corner in nature and they appeared before me and reminded me of my Pleiadian heritage and my mission this lifetime.

Nevertheless so profound is our ignorance, and so high our presumption, that we marvel when we hear of the extinction of an organic being; and as we do not see the cause, we invoke cataclysms to desolate the world, or invent laws on the duration of the forms of life!

I am a profound pessimist both about life and about human relations and about politics and ecology. Humans are inadequate and stupid creatures who sooner or later make a mess, and those who are trying to do good do a lot more damage than those who are muddling along.

You have this big challenge going on within the Democratic Party, and many of them coming into the Greens. So there is the potential for a really profound realignment here. And remember most of this is going on with most voters not having any idea who our campaign is.

The human mind delights in finding pattern—so much so that we often mistake coincidence or forced analogy for profound meaning. No other habit of thought lies so deeply within the soul of a small creature trying to make sense of a complex world not constructed for it.

The movie that really 'did it for me' was 'All About Eve.' The backstage feeling, the authenticity, the passion those people had for their lives in the theater. I must say, the movie 'All About Eve,' what a great movie! 'All About Eve' had a profound effect on my life.

In death - no! even in the grave all is not lost. Else there is no immortality for man. Arousing from the most profound slumbers, we break the gossamer web of some dream. Yet in a second afterward, (so frail may that web have been) we remember not that we have dreamed.

There is no reason why the profoundest thoughts should not make easy and exciting reading. A profound thought is an exciting thing as exciting as a detective's deductions or hunches. The simpler the words in which a thought is expressed the more stimulating its effect.

Anyone who enjoys inner peace is no more broken by failure as he is inflated by success. He is able to fully live his experiences in the context of a vast and profound serenity, since he understands that experiences are ephemeral and that it is useless to cling to them.

I used to listen to Judy Garland all the time - I love Judy Garland and her music. But I started to realize that if you keep singing like that, singing songs of being victimized by love over and over and over again, it can't help but have a profound effect on your life.

In certain strains of Judaism, there's a profound passion for the ineffable. Contemplation of God is meant to be forever elusive, because, you know, our tiny minds can't possibly comprehend Him. If we find ourselves comprehending Him, then we can be sure we're off track.

I love New York City in the fall, and one of my favorite events of the season is the annual World of Children Award Gala, at which I have the profound pleasure of meeting the newest class of changemakers for children who are there to receive their World of Children Award.

Like many astronomers who use the great telescopes on Mauna Kea, I have participated personally and joyfully in ceremonies to celebrate the profound cosmic understanding that comes from joining ancient Hawaiian navigator traditions with the techniques of modern astronomy.

When you talk to astronauts, the most profound thing when you finally go into space is the view - looking back at the planet - so I absolutely know for sure that that's going to change my perspective on our planet, and it's going to change my perspective on life, I think.

I always let my husband read the script so he knows what's about to happen to his wife. When I played Cheryl Strayed in Wild, I'd get really mad about certain things, I'd say really profound things, and I'd curse out of nowhere. He'd say, "Are you you, or are you Cheryl?"

Order, for a liberal, means only peace; and the hope of a profound peace was one of the chief motives in the liberal movement. Concessions and tolerance and equality would thus have really led to peace, and to peace of the most radical kind, the peace of moral extinction.

In Tantrism, the first thing is having the experience of touch, of profound contact with things, with the universe, without mental commotion. Everything begins there: touching the universe deeply. When you touch deeply, you no longer need to let go. That occurs naturally.

We're in the second golden age of television, and to me, one of the most profound things that's happening in TV is just that by default that opened the door to more women, more people of color, more outliers. It's one of the greatest side effects of the digital revolution.

At a finite distance in the future, a critical state of encounter will occur, an ultimate co-reflective Center. A focused conspiration will allure individual persons to identify with others in profound affinity. Because of thinking altogether, love will grow into Divinity.

The racism is so profound and the recognition - the kind of deep recognition that you have to humiliate. It's not about to killing or torture. It's to humiliate. So the oppressed feel degraded. And both the oppressed understand and the oppressors understand. It's constant.

The life that intends to be wholly obedient, wholly submissive, wholly listening, is astonishing in its completeness. Its joys are ravishing, its peace profound, its humility the deepest, its power world-shaking, its love enveloping, its simplicity that of a trusting child.

I have a little sister, and I'm constantly annoyed [by] how terribly written most females are in most everything - and especially in comedy. Their anatomy seems to be the only defining aspect of their character, and I just find that untrustful and it straight-up offends me.

The bottom line is that this author, a practicing neurologist dealing with Alzheimer's disease on a daily basis, believes we need to expand the public awareness that modifiable lifestyle factors have a profound role to play in determining who will or won't get this disease.

That's human nature - we want to completely rewrite history so it can be comfortable. Without getting too profound, I'm pretty sure that's where the invention of the afterlife comes from. "We don't really become worm food. We go to a magical place with bunnies and rainbows."

I would say that, first of all, if you have the honor of being chosen to produce the Oscars, you usually get only one crack at it. We were the first people in sixteen years to do it three times in a row, and it was one of the most profound experiences you could ever imagine.

I think that music is crucially important in Shakespeare - and, clearly, was an important part of the Elizabethan theatre. And, it's always been something that was a profound element of the experience of Shakespeare that I have been drawn to - and interpreters have, as well.

Upon the profound discontent of the young in every country do I set my faith. I beg you, the young, to be discontented. I pray that you may rebel against what is wrong, not with feeble negative complaining but with strong positive assertion of what is right for all humanity.

Boredom is the most sublime of all human emotions because it expresses the fact that the human spirit, in a certain sense, is greater than the entire universe. Boredom is an expression of a profound despair at not finding anything that can satisfy the soul's boundless needs.

The way you speak to a team is very important - both before a Test and during the game itself. If you try and do things on the run then people will quickly see through you. You're also never going to say anything that profound and so it's important to come up with new angles.

The Russian drama began at the end of 1991, when the Soviet Union mercifully ended. Russia and 14 other new countries emerged from the ruins of the Soviet Union. Every one of those 15 new states faced a profound historical, economic, financial, social and political challenge.

I have a profound admiration for Fellini. I met him lately and he's just fantastic. I feel very close to him even though he's very Italian. But his films could have been made in every country. When I say, I feel close to him, then also because we're both born on January 20th.

The diversity of life on Earth, generally, is astonishing. But despite those large numbers, it's also important to recognize that every species, one way or another, is vulnerable to extinction. And in our time on Earth... our impact on the diversity of life has been profound.

When you're talking with a person at this level of the government, at the very highest level, I think you have to be very discreet because he, President Clinton, is very aware that anything he says publicly can have a profound impact on American politics and on world politics.

I'm just becoming more and more aware of this truly profound responsibility that we carry as individuals. And it's a responsibility not only to ourselves and to our families, but to the billions of people who still have to come in the future who will be dealing with our legacy.

Delphine Lucielle's paintings are profound, unique, and moving. It is rare to find contemporary art that combines both beauty, innovation, and creates a new style of painting by fusing technology and nature. Delphine Lucielle is pushing the boundaries of what art is capable of.

I do realise and understand very well on a profound level how lucky I am and what a privileged position it is and what it's done ultimately for me, my family and my kids. But at the same time, there are moments in a man's life when you just kind of want to feel somewhat normal.

Our late Leader, Dr. Sun Yat-sen, with his universal sympathy for all oppressed and his profound understanding of Jesus' revolutionary spirit of love and sacrifice, carried on his revolutionary work for forty years and brought about at last the liberation of the Chinese people.

This non-proletarianised plebs has been racialist when it has been colonialist; it has been nationalist - chauvinist - when it has been armed; and it has been fascist when it has become the police force.These ideological effects on the plebs have been uncontestable and profound.

Here's my rule: You always want to pay cash for your own books, because if they look at the name on the credit card and then they look at the name on the book jacket, then there's this look of such profound sympathy for you that you had to resort to this. It really is withering.

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