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From what has been said, it would appear that the possibility of thyroid deficiency should be considered, and if found, should be treated in any woman with a menstrual abnormality or a reproductive problem. It was generally agree that correction of thyroid deficiency solved many such abnormalities and problems - until about 1940.
Many of the women who benefited from thyroid therapy provided added evidence that it was the thyroid which was responsible. There were the women who, upon being relieved of their {menstrual} problems, stopped taking medication only to return in a few months with their original complaints. Thyroid therapy again overcame their difficulties.
Certainly miscarriage is not invariably related to low thyroid function. There are many other possible causes. Yet soon after thyroid therapy first became available, it was found that patients with a history of miscarriages often had a history compatible with thyroid deficiency and that full-term pregnancies might follow treatment with thyroid.
As stated before, hypothyroidism may cause premature or delayed puberty. The majority of normal and hypothyroid females begin their cycle at ages 12 or 13. However, a growing number of those with hypothyroidism start their cycle years earlier or begin their periods at age 15 or later. Premature or delayed puberty in males is also becoming more common.
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Problems associated with the menstrual cycle are now commonplace. The majority of teenagers whom I have seen suffer problems such as PMS, severe cramping, and irregular or heavy cycles. Severe hypothyroidism may cause the menses to stop. Dr. Barnes noted his patients with menstrual problems usually suffered many other telltale symptoms of hypothyroidism. Mine do as well. A large majority of menstrual problems resolve after treatment with dessicated thyroid.
It is generally assumed that recurrent miscarriage may be due to progesterone deficiency, hypothyroidism or vitamin E deficiency and should be treated in theses cases with progesterone, thyroid extracts and vitamin E respectively. In theory, thyroid therapy appears to be the least well-founded, especially when applied to women without manifest signs of hypothyroidism, yet among the measures mentioned above it is most frequently claimed to have been successful.
