The thing that makes my generation The Greatest is our ability to hang out. We're spectacular at it. If you take somebody from my generation and sit them on a couch and bring them food and plumbing, they'll sit there and talk to you about anything you want until the day you die.

When I was a child, doctors sent my grandmother home in a wheelchair to die. Diagnosed with end-stage heart disease, she already had so much scar tissue from bypass operations that the surgeons had essentially run out of plumbing. There was nothing more to do, they said; her life was over at 65.

Water is commonly regarded as the 'solvent of life,' since our bodies are 70% water. All other vertebrates, invertebrates, microbes, and plants are also primarily water. The organization of water within biological compartments is fundamental to life, and the aquaporins serve as the plumbing systems for cells.

In the 1920s, a generation before the coming of solid-state electronics, one could look at the circuits and see how the electron stream flowed. Radios had valves, as though electricity were a fluid to be diverted by plumbing. With the click of the knob came a significant hiss and hum, just at the edge of audibility.

We have grown accustomed to the wonders of clean water, indoor plumbing, laser surgery, genetic engineering, artificial joints, replacement body parts, and the much longer lives that accompany them. Yet we should remember that the vast majority of humans ever born died before the age of 10 from an infectious disease.

The plumbing and pluvial dynamics of the Amazon, the largest freshwater system on Earth, are still far from understood. This is partly because it is a semi-open system. Moisture flows in and out unpredictably. A lot of nonlinear feedback loops and 'remote influences' - continental, transcontinental, oceanic, meteorological - come into play.

One time at the University of Colorado, at a faculty dinner, this professor said to me, 'Well, my goodness, a boy from Appa-lay-chee-a with a Ph.D!' The dinner was in her house. And I said, 'My grandparents didn't have indoor plumbing, but they had more books in their house than you do.' I was a little insulted by the Appa-lay-chee-a business.

I ushered at the Shubert in New Haven during graduate school when plays en route to Broadway still went out of town to try out. I worked backstage at summer stock doing jobs from garbage man to strapping on Herbert Marshall's wooden leg to fixing Gloria Swanson's broken plumbing in her dressing room with her yelling at me as I worked the plunger.

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