Understanding how Cas9 is able to locate specific 20-base-pair target sequences within genomes that are millions to billions of base pairs long may enable improvements to gene targeting and genome editing efforts in bacteria and other types of cells.

My mama never wore a pair of pants when I was growing up, and now that's all she wears. It was so funny for me when I first started seeing Mama wear pants. It was like it wasn't Mama. Now I've bought her many a pantsuit because she just lives in them.

My perspective is hard because I look at wardrobe from very much a guy's perspective. You look at my closet and I have pairs of black jeans and five button-downs, but one's silk, one's cotton. They all are slightly different, so that's my perspective.

Romance only dies with life. No pair of pincers will ever pull it out of us. But there is a spurious sentiment which cannot resist the unexpected and the incongruous and the grotesque. A touch will loosen it, and the sooner it goes from us the better.

I need to have a quick wardrobe. Two or three blazers with dark gray pants, two pairs of jeans, two light blue shirts, a casual shirt, two pairs of shoes, one formal one not. Small accessories like Tod's Greca belt and our woven bracelets for a wild touch.

My eyes are too big, my nose is too flat, my ears stick out, my mouth is too big and my face is too small... my body is thin as a clarinet and my ankles are so skinny that I wear two pairs of bobby socks because I don't want people to see how thin they are.

In the gametes of an individual hybrid the Anlagen for each individual parental character are found in all possible combinations but never in a single gamete the Anlagen for a pair of characters. Each combination occurs with approximately the same frequency.

English suspenders not American. Could you imagine? Just a pair of knickers and some suspenders. I don't know. How would you wear that? I think this is kind of a cute first date look. A mini sixties Ossie Clark inspired mini dress with a pair on your trotters.

Skinny jeans are usually my go to jean. I do bootleg every once in a while, boyfriend jeans I feel like are so hard to pull off! Skinny jeans are very easy and you can kind of pair anything with them and it will work: heels and boots or nice top or flouncy top.

Only flies have true halteres. In fact, the scientific term for flies, 'diptera,' means 'two wings.' Most insects, including bees, have two pairs of wings for a total of four. In flies, the hindwing pairs have been transformed through evolution into the halteres.

I'm at like 325 pairs right now, give or take. But I've given away about 200 pairs of sneakers. I'm not as big of a collector as I used to be, because I think the game just got weird. Everybody likes to collect now, so it's kind of corny. But I got the essentials.

My varying pairs of legs can be quite practical or quite impractical, and I don't judge them either way. Some are for getting around a 12-hour day, pounding the pavement, and some are to feel like I can transform my own body into a workable, changing piece of art.

The strands of the DNA double helix are held together by hydrogen bonding interactions between the complementary base pairs. Heating DNA in solution easily breaks these hydrogen bonds, allowing the two strands to separate - a process called denaturation or melting.

Then you will simply have to see for yourself. Touch me, lass. Feel my ...sock." His silver gaze sizzled with challenge, as he unzipped his zipper. Uh-uh." She shook her head for added emphasis. Then find me a pair of trews that doona threaten to sever my manparts.

The idea of an animated film is you always kind of get a little bit daunted by it as a filmmaker because it feels like a lot of your communication is going to be with computer artists, and you're going to have to kind of channel the movie through extra pairs of hands.

Right after high school, I moved to Rio and took classes to become a technician for a manufacturing factory where you had to figure out how to produce 3,000 pairs of jeans. But in Rio, I was by myself, which was very liberating, being so young. I got to do my own thing.

No sooner met but they looked; no sooner looked but they loved; no sooner loved but they sighed; no sooner sighed but they asked one another the reason; no sooner knew the reason but they sought the remedy; and in these degrees have they made a pair of stairs to marriage.

Want to train a machine translation system? Train it on a gazillion pairs of sentences of parallel corpora, and that creates a lot of breakthrough results. Increasingly, I'm seeing results on small data where you want to try to take in results even if you have 1,000 images.

When it comes to underwear, there's nothing worse than a visible panty line. Sometimes it seems like nobody knows that seamless underwear exists. But Calvin Klein makes them. Commando makes them. Hanky Panky makes them. You don't need a drawer full; a few pairs will suffice.

I have a couple of go-to sneakers off the pitch. I like to have shoes that I can slip on and wear with anything. I travel often, so it's about finding those two or three pairs of shoes that can go with any outfit, whether they go with leggings or a skirt or a dress or jeans.

Man is in a transition stage; he has 31 pairs of spinal nerves which keys him to the solar month, but the nerves in the so-called cauda-equina - literally horse-tail, at the end of our spinal cord, are still too undeveloped to act as avenues for the spiritual ray of the sun.

People always like to have a good time and laugh, and, [among] the vast majority of the seven billion people on this earth, one thing that we all have in common is at some point we all need to pair up and find some sort of significant other, some sort of romantic counterpart.

There's something about that puritanical narrative of progress and upward mobility and work ethic that the glorification of abstinence fits pretty neatly into. That pairs with the fact that 12-step recovery has had too large a monopoly on how treatment is understood in America.

If you have to mask the things you're insecure about, go ahead. Wear four pairs of pantyhose, pad your hips, boost your boobs - whatever it takes to walk out of the house feeling like you own the world. Because there's no reason to waste your life hating something you can change.

I'm one of those girls that, day-to-day, I'm in trainers or Converse. I have about 50 pairs of trainers, so when I get the chance to dress up, I will definitely be in heels. 100 percent. I might take some battered Converse in my bag to wear at the after-party when my feet are tired.

A pair of jaybirds came up from nowhere, whirled up on the blast like gaudy scraps of cloth or paper and lodged in the mulberries, where they swung in raucous tilt and recover, screaming into the wind that ripped their harsh cries onward and away like scraps of paper or of cloth in turn.

The most real characters in a great play are those who are so meticulously drawn that the audience could predict how many pairs of shoes they might have in their closet or how many close friends they had in grade school. Have any of our public figures been as fully developed in the media?

While at a biological disadvantage in competitions, women - who even make trips to restaurant bathrooms in pairs - are at a clear advantage when it comes to grouping together and the activities that accompany it: gossiping, sharing, bonding, assisting, scrapbooking, and building networks.

Ah, the power of two. There's nothing quite like it. Especially when it comes to paying utility bills, parenting, cooking elaborate meals, purchasing a grown-up bed, jumping rope and lifting heavy machinery. The world favours pairs. Who wants to waste the wood building an ark for singletons?

I was seized on the 8th of June, 1824, in consequence of the war with Bengal and, in company with Dr. Price, three Englishmen, one American, and one Greek, was thrown into the death prison at Ava, where we lay eleven months - nine months in three pairs and two months in five pairs of fetters.

A fellow once came to me to ask for an appointment as a minister abroad. Finding he could not get that, he came down to some more modest position. Finally, he asked to be made a tide-waiter. When he saw he could not get that, he asked me for an old pair of trousers. It is sometimes well to be humble.

Pick up a pinecone and count the spiral rows of scales. You may find eight spirals winding up to the left and 13 spirals winding up to the right, or 13 left and 21 right spirals, or other pairs of numbers. The striking fact is that these pairs of numbers are adjacent numbers in the famous Fibonacci series

One can't say how one behaved or why, really. Such situations, they are far more complex than any either/or proposition. It is simplistic to produce events in pairs and lean them against each other like cards. I suppose if you a playing go or shogi, then such a thing might be helpful, but that is not life.

We've seen black holes, which is already wonderful. We also expect to see the merger of neutron stars, and that was a thing that actually gave this field a certain credibility when it was discovered that there were pairs of neutron stars in our galaxy, and people stopped laughing at us when that was found out.

I probably have over a hundred pairs of high-heel shoes. I collect them. Over however-many years, from, like, the mid-'80s on - yes, I'm that old - I've been in drag several times in my life, and I collect a lot of stuff, and I do have a lot of high-heel shoes that I'm sure a lot of people would be jealous about.

When I was a kid, dressing right and looking good was a priority. As I grew up, I just wanted to stay that way, stick out a bit and have my own thing. That's where white belts and wearing some colors started. So signing with Puma was a great fit for me. I usually travel with nine pairs of golf shoes and 10 belts.

Oh yeah, I'm literally walking through my house now looking down and there are maybe, like, 15 pairs on the floor. For real. Real talk. It's just simplicity. They're something I wear every day. Before I got a deal with them, I was wearing some type of Vans all the time. I would just order them by the box, like, 10 at a time.

First of all, I appropriate photographs.In presenting the Richard Prince photograph I tried to be as neutral as I could be. I put down the fact of it. I wanted it to be the same thing he wanted it to be, an open ended invitation to think about authorship, and who owns a created work. So I pair it with my appropriated picture.

I don't think I'm a workaholic. Every weekend, I invite my colleagues and friends to my home to play cards. And people, my neighbors, are always surprised because I live on the second floor apartment, and there are usually 40 pairs of shoes in front of my gate, and people play cards inside and play chess. We have a lot of fun.

Some people - which I don't understand - kind of get mad like I'm disrespecting shoes. I'm like, 'They are sneakers, they are meant to be worn, meant to be played in.' And I hate when people use them as trophies. They are sneakers. It's one of my pet peeves. I got pairs if I don't want to wear, I will get a couple pairs of them.

It's tough for me to get rid of clothes. I grew up in a household with a limited budget and we really had to make our nice clothes last, and so now I'll get free pairs of shoes and this, that and the other and I'll be like, 'Oh great!'; even though it stresses me out that I don't have enough room to put them, I can't throw them away.

I always say to people, the Eighties were so inventive because people wanted to stand out. By the time we got to the Nineties, everyone wanted to fit in. It was all about having the same pair of trainers and the same pair of jeans. That's fatal. Whereas the Eighties you would never be seen in the same pair of jeans that somebody else was wearing.

Women are extraordinary in lacking the estrus, or period of heat. The females of most other primate species become sexually active, to the point of aggression, only at the time of ovulation. Why has sexual responsiveness become nearly continuous? Unusually frequent sexual activity between males and females served as the principle device for cementing the pair bond.

She had heard it said that, before you could understand anybody, you needed to walk a mile in their shoes, which did not make a whole lot of sense, because probably AFTER you had walked a mile in their shoes, you would understand that they were chasing you and accusing you of the theft of a pair of shoes--although, of course, you could probably outrun them, owing to their lack of footwear.

The man who cannot wonder, who does not habitually wonder (and worship), were he President of innumerable Royal Societies, and carried the whole Mecanique Celeste and Hegel's Philosophy, and the epitome of all Laboratories and Observatories with their results, in his single head, is but a Pair of Spectacles behind which there is no Eye. Let those who have Eyes look through him, then he may be useful.

Corrigan told me once that Christ was quite easy to understand. He went where He was supposed to go. He stayed where He was needed. He took little or nothing along, a pair of sandals, a bit of a shirt, a few odds and ends to stave off the loneliness. He never rejected the world. If He had rejected it, He would have been rejecting mystery. And if He rejected mystery, He would have been rejecting faith.

Listen," I began, "this is an established,traditional form that-" "Traditional nothing.Where are your clothes?" "Clothes?" I said weakly. "I don't normally bother with them in this guise." "Well,you could put on a pair of shorts,at least.Your not decent." "I'm not sure they'd go with the wings..." The demon frowend,and blinked."Hold on,enough of this." "Lenderhosen would. They'd compliment the leather.

A pair of dolphins swept by us in the water, flicking their heads out to get a look at us as they went. One of them made a chittering sound that wasn't very melodic. The other twitched its tail and splashed a little water our way, all in good fun. They weren't the attractive Flipper kind of dolphins. They were regular dolphins that aren't as pretty and don't get cast on television. Maybe they just refused to sell out and see a plastic surgeon. I held up a fist to them. Represent.

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