I find the female tragedy of insecurity to be hilarious. We get obsessed over issues like the tiny skin tags on our backs or that we're fat. You read one line in a magazine and it sends you into a tailspin.

Marvin Bell always looked very closely at how lines could break, how you could put over one line into the second line. How you could stop the line two or three times within the line: You could make it stop.

When I hear somebody like Hayes Carll write a song that's touching and poignant and sad and funny all at the same time, it motivates me to step my game up and try to figure out a way to get more different emotions into one line or one song.

When we first started 'The Big Bang Theory,' I would get incredibly nervous because it's such a big show and I was just out of graduate school. I'd come in and have this huge responsibility for the one line that everyone hopes will bring down the house.

After doing 'Life After Beth,' which I think had one line that wasn't scripted, everything was scripted so that it sounds natural, and I went to such great lengths to create dialogue and to come across the way that people wouldn't sound like they were on the nose.

I think I do have a way of predicting - not always accurately - what is a nerve-wracking day for actors, what may be a difficult scene or a difficult moment, how small - and it may be down to one line - a thing maybe that is upsetting or undermining a performance.

I went down to my keyboard and was playing random chords, and the one line I kept repeating was, 'I'm a lost boy from Neverland.' I decided to post it to Vine, and it got the biggest reaction I'd ever gotten. People wanted to hear more, and I had to explain it wasn't a song.

One line I'd draw would be on raising the eligibility age for Social Security and Medicare. It sounds fair, since people are living longer. But it isn't. Lower income workers are the ones who find it hardest to keep working after 65. And they'll get penalized with lower benefits.

I like playing characters that are complex, that are intriguing, that come from left field, that do things that are unexpected. I don't like people who just follow one line and that's it - that's why I could never be in a sitcom, I don't think. They're not intriguing enough for me.

One of the reasons you take a role is because it's something you always wanted to do, from going to the movies as a kid. I always wanted to do a 1950s movie, for example. And I got a chance to be in 'Peggy Sue Got Married.' I would have taken only one line of dialogue to be in that.

I did about 10-12 national commercials and then got one line parts in things like 'Curb Your Enthusiasm' and the show 'The Unit.' Got a little part in the movie 'Redbelt' by David Mamet and kept slowly grinding up and then started getting bigger parts in independents and getting noticed by Liz Meriwether.

I think it's still kind of weird to memorize a line, because you're supposed to 'be' this person, you know? So then its like, if I'm really this person, how can I be in the moment if I know there's just one line I'm supposed to say? It doesn't feel natural. I always just kind of want to say whatever comes up.

I kind of found a niche for myself after 'Firefly'. I found something that I enjoyed doing and that I did well, but as far as how I seek out a part, it's always different. It's always something that lights you on fire when you read it. It might be just one scene, it might be one line that defines the character for you.

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