The nature of catastrophe is, after all, reasonably unvarying in the way it ruins, destroys, wounds and devastates. But if something can be learned from the event - not least something as profound as the theory of plate tectonics - then it somehow puts the ruination into a much more positive light.

I'm no Buddhist monk, and I can't say I'm in love with renunciation in itself, or traveling an hour or more to print out an article I've written, or missing out on the N.B.A. Finals. But at some point, I decided that, for me at least, happiness arose out of all I didn't want or need, not all I did.

My first joke that ever aired on 'Late Night' was for a list of 'Top 10 Least Popular Summer Camps.' My contribution - 'Camp Tick in beautiful Lyme, Connecticut' - squeaked in at No. 10. Like a trip to Camp Tick, my time at 'Late Night' faded into memory like a short session at a dicey summer camp.

Films are not mathematics - that's the first thing you need to understand. At least, that's how I feel. They are not words on paper. Films are made with people, with teams and with individual bundles of creativity coming together to fulfill the vision of an individual who is the director of the film.

To me, it remains incomprehensible that a people who can design the Porsche 911 and sleek, white ice trains, who created the Bauhaus and speak at least three languages at birth, want to own twee Christmas figurines painted in gaudy colours, dress up in Bavarian lederhosen, and eat Haribo gummy bears.

Socialism violates at least three of the Ten Commandments: It turns government into God, it legalizes thievery and it elevates covetousness. Discussions of income inequality, after all, aren't about prosperity but about petty spite. Why should you care how much money I make, so long as you are happy?

The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.

The money I have made and will be making means nothing to me compared to the fact that about half of the black people I meet - ranging from the most sophisticated to the least sophisticated - say to me, 'I'm proud of you.' I feel strongly about always earning that and never letting black people down.

Any government, that is its own judge of, and determines authoritatively for the people, what are its own powers over the people, is an absolute government of course. It has all the powers that it chooses to exercise. There is no other or at least no more accurate definition of a despotism than this.

One of the many American ideals that make no sense at all is that we're all a million rugged individualists marching in lockstep. We dress accordingly, at least the men. If it's always been thus, I yearn for the halcyon days of the man in the gray flannel suit because at least that guy had some flair.

I believe that every character is a setting, a world with moving parts, and on the other hand, every setting is, in fact, a character - a living breathing thing with personality and backstory. The way stories come to life, at least for me, is when these elements commune in relationship to one another.

The first point to remember is that attempts to clone mice have actually been very unsuccessful for at least a decade. Sheep have been successful. So one asks, 'Where do humans lie?' Most people think they are somewhere between the two, but at least there's a reasonable chance they might be clone-able.

I initially thought 'Lewis' was a terrible idea. The character had very much been Morse's work donkey and sounding board. But I was persuaded to do it, thinking if it was a flop, at least ITV would stop asking me. But the pilot took off, so we got back on this moving train, and we've never looked back.

I went to Mumbai thinking I will be away from media and fans, but right from the Governor of Maharashtra to aam janata, at least 60 people would come to visit me every day. There were calls, messages and I was so touched. I didn't know that people loved me so much and they want to see me back in action.

Keep both heart and hand in your own possession, till you see good reason to part with them; and if such an occasion should never present itself, comfort your mind with this reflection: that, though in single life your joys may not be very many, your sorrows, at least, will not be more than you can bear.

I will check the internet for at least an hour every morning scanning worldwide news to do with child abuse. So if you're constantly putting yourself in an environment where you're checking up on social economics or homelessness problems, if you keep yourself aware of it, you don't really have a day off.

What I like best is a book that's at least funny once in a while. What really knocks me out is a book that, when you're all done reading it, you wish the author that wrote it was a terrific friend of yours and you could call him up on the phone whenever you felt like it. That doesn't happen much, though.

I initially decided to speak about my anorexia and bulimia, partly out of a selfish motivation. I felt I had been scrutinised for my weight and thought, 'At least judge and criticise me on the facts.' There was a freedom with that. Now it's out there, and I just get on with life. I'm at peace with things.

For me, writing is a job. I do not separate the work from the act of writing like two things that have nothing to do with each other. I arrange words one after another, or one in front of another, to tell a story, to say something that I consider important or useful, or at least important or useful to me.

But as an adult working in the fashion industry, I struggle with materialism. And I'm one of the least materialistic people that exist, because material possessions don't mean much to me. They're beautiful, I enjoy them, they can enhance your life to a certain degree, but they're ultimately not important.

And we should keep our minds open, or at least ajar, to concepts on the fringe of science fiction. Flaky American futurologists aren't always wrong. They remind us that a superintelligent machine is the last instrument that humans may ever design - the machine will itself take over in making further steps.

I don't believe that if you do good, good things will happen. Everything is completely accidental and random. Sometimes bad things happen to very good people and sometimes good things happen to bad people. But at least if you try to do good things, then you're spending your time doing something worthwhile.

Senseless violence is, almost by definition, hard to understand. Not that I can understand terrorists who kill from hate, but at least we can identify a reason - a terrifying one, to be sure, grounded in a violent belief system - for what they do. Two gangs go to war. Extremists kill in the name of belief.

Sometimes what we call tragedy, at least in the theater, are really case histories. They're based on the central figure, and things happen to that person, and they're called tragedy because they're extremely sad. But tragedy always has a glorious thing happen at the end of it. That's what the catharsis is.

But I think it's more that when you're young, you're invincible, you're immortal - or at least you think you are. The possibilities are limitless, you're inventing the future. Then you get older and suddenly you have a history. It's fixed. You can't change anything. I find that a bit disturbing, to be honest.

My father spent all those years building his brand. I happen to be his namesake, and I also happen to be the president of the largest Christian university. I think I have a responsibility to be a good citizen. The least I can do is to lend my name and whatever influence I have to make a difference politically.

I've never been much of a computer guy at least in terms of playing with computers. Actually until I was about 11 I didn't use a computer for preparing for games at all. I was playing a bit online, was using the chess club mainly. Now, obviously, the computer is an important tool for me preparing for my games.

I suppose even when I was growing up, I noticed I was most happy when I was absorbed in something, lost in the moment and forgot the time, whether was conversation, movie, or a game I was playing. That was my definition of happiness. And I was least happy when I was all over the place, distracted and restless.

Obviously it's much easier to say that you're going to follow your passions when you're financially secure, but at least we can take solace in the fact that we now have the time to pursue the things that we really want to pursue because now the option of doing things just for the money isn't necessarily there.

There's been times where I sold the place out, and I walked in and the guy's like, 'Uh, ID?' 'No, you can't ID me, man. I just sold this place out.' People are just doing their jobs, but I think if you're working the door at a venue where there's a headliner, you should at least be like, 'OK, this is the dude.'

One of the principal goals in my life has been to avoid embarrassing my children by doing the job I do. I hope I've managed to do that, and I hope that, with the job I'm in now, they are, if not proud, at least unembarrassed by it. I must say, my three are most agreeable children, who do nothing but delight me.

America traditionally represents the greatest possibility of someone's going from nothing to something. Why? In theory, if not practice, the government stays out of the way and lets individuals take risks and reap rewards or accept the consequences of failure. We call this capitalism - or, at least, we used to.

I have a type of bipolar that swings up and down all day long. There are significant mood swings within a day, within a week, within a month. I go through at least four major episodes a year. That's really the definition of bipolar rapid cycle. But I have ultra-rapid, so I have tiny little episodes all day long.

It's an amusing idea to some, this feminism thing - this audacious notion that women should be able to move through the world as freely, and enjoy the same inalienable rights and bodily autonomy, as men. At least, that's the impression given when feminism and feminists are all too often the targets of lazy humor.

Every time I sit down in front of my piano, I like to improvise with the instrument. It depends on my mood of that day what kind of melodies and rhythms I am playing around. Sometimes, even before starting to play I already have a quite clear picture of a song I would like to compose, or at least the sound of it.

If you walk into a room and one hundred people say, 'You are a lovely, beautiful person', who isn't going to be affected by that? But you have to tell yourself not to value that. You have to tell yourself - or at least I do - to not become accustomed to hearing applause in any way, because I think that's dangerous.

My protest about the post exchange seating bore some results. More seats were allocated for blacks, but there were still separate sections for blacks and for whites. At least I had made my men realize that something could be accomplished by speaking out, and I hoped they would be less resigned to unjust conditions.

Fraud is common when you give away billions. Fraud related to Hurricane Katrina spending is estimated to top $2 billion. In addition, debit cards provided to hurricane victims were used to pay for Caribbean vacations, NFL tickets, Dom Perignon champagne, 'Girls Gone Wild' videos, and at least one sex change operation.

I think at the beginning of a project, you decide if you're in love with the idea and what it's about, or what you think it's about at that time at least. Then you commit to it, and once you've commit to it no matter what, no matter how many self doubts you have, you're in it. The ship's sailed, you can't turn around.

The vegetable life does not content itself with casting from the flower or the tree a single seed, but it fills the air and earth with a prodigality of seeds, that, if thousands perish, thousands may plant themselves, that hundreds may come up, that tens may live to maturity; that, at least one may replace the parent.

You stand with the least likely to succeed until success is succeeded by something more valuable: kinship. You stand with the belligerent, the surly and the badly behaved until bad behavior is recognized for the language it is: the vocabulary of the deeply wounded and of those whose burdens are more than they can bear.

The busyness of life can keep you running from one activity to the next. If you never step back to consider whether all those activities are really how you want to spend your time, you could miss out on building the kind of life you want. Devote at least 10 minutes each day to examining the bigger picture in your life.

Making loans and fighting poverty are normally two of the least glamorous pursuits around, but put the two together and you have an economic innovation that has become not just popular but downright chic. The innovation - microfinance - involves making small loans to poor entrepreneurs, usually in developing countries.

At least once a year, I meet with a group called the Giving Pledge. It's a group of billionaires - including me, Warren Buffett, Bill Gates, and Ted Turner - who have pledged to give away most of their money to charity. We meet for three days to talk about what we're doing to help make the planet a better place to live.

The government's desire to expand global trade may be understandable, but we mustn't give away too much. We must tell our elected representatives to at least delay the Canada-China FIPA until it has been examined more thoroughly, and to reconsider the inclusion of investor-state arbitration mechanisms in all trade deals.

Each year, thousands of UFOs are sighted and reported, which is an impressive tally of unidentified aerial phenomena. Surveys show that roughly one-third of the populace believes that at least some of this sky show is due to extraterrestrial spacecraft, here to probe our airspace and, when that proves boring, our bodies.

The preservation of peace and the guaranteeing of man's basic freedoms and rights require courage and eternal vigilance: courage to speak and act - and if necessary, to suffer and die - for truth and justice; eternal vigilance, that the least transgression of international morality shall not go undetected and unremedied.

Isaiah is by far the finest and least objectionable of the seventeen prophets whose supposed productions form the latter part of the Old Testament. A distinctly higher moral tone appears in the writings called by his name, and this is especially noticeable in the 'Second Isaiah,' who wrote after the Babylonish captivity.

Kids don't need to be taught the value of making; they are natural makers, at least until traditional education makes them afraid of making mistakes. The long-term value of making for kids is in learning to become an active participant in the world around them rather than a consumer of prepackaged products and solutions.

In football, it's the job of the player to play, the coach to coach, the official to officiate. Each guy is charged with upholding his end, nothing more. In golf, the player, coach and official are rolled into one, and they overlap completely. Golf really is the best microcosm of life - or at least the way life should be.

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