The United Nations has an irreplaceable role in dealing with global issues. While other international bodies play important roles, the U.N. is the only truly global arena where we can achieve results for the global good.

It's a very naive idea to think that the chef is cooking everything, and, on top of it, is irreplaceable. That would mean that basically he is the only genius, and there are idiots all around him, which doesn't make sense.

If you're lucky enough to have a permanent position, don't feel entitled. Companies value longtime employees' institutional memory, but to be irreplaceable, you must stay invested. Take the initiative and assume new responsibilities.

If there is one thing BP's 'watery improv act' made clear, it is that, as a culture, we have become far too willing to gamble with things that are precious and irreplaceable, and to do so without a back-up plan, without an exit strategy.

Regarding themselves as irreplaceable, both Lenin and Stalin tried in different ways to destroy their successors - Lenin through a testament that attacked Stalin and Trotsky, Stalin through purges culminating in the Doctors' Plot of 1953.

Exercising power can do strange things to people. You can become convinced that you're irreplaceable. You can become convinced that you're always right. And I think the danger is the longer you stay in power, the more likely that is to happen.

We believe with all the strength of our spirit that mankind has a supreme, primary and irreplaceable need which can be satisfied only through Jesus Christ, the first-born among men, the head of the new humanity, in whom each individual reaches full self-realization.

Medical judgment can be taught - laboriously, in long periods of training - but it cannot be neatly handed over as the occasion demands it. It is the irreplaceable and untransferable contribution that the healer makes to the suffering individual who would be healed.

You may be guided by the unending effort of poets and artists, biologists and psychiatrists to describe that irreplaceable and still mysterious emotion so essential to the human condition, but all the search engines in the universe cannot compete with the first kiss.

I like to take walks and getting out and seeing things. These experiences are so irreplaceable and give you a whole different perspective on the greater context that you're in. If I didn't try to take advantage of that, I'd be missing out on a lot of really interesting things.

Do not do what someone else could do as well as you. Do not say, do not write what someone else could say, could write as well as you. Care for nothing in yourself but what you feel exists nowhere else. And, out of yourself create, impatiently or patiently, the most irreplaceable of beings.

Certainly the highest posthumous praise that can be conferred upon any writer is the assertion that his or her writing permanently altered the literary landscape for the better, opening new textual doors and engaging new readers. That the author's oeuvre was essential and irreplaceable and transformative.

Israel's pro-American orientation exists not just among Israeli elites but also among the whole population. Come what may in Israel, it's inconceivable that this fundamental orientation will change. Combined with its overwhelming military power, this makes Israel a unique and irreplaceable American asset in the Middle East.

The exploration of space: Be it by humans or robots, based on the best choice for the mission and the most efficient means to return the data and science sought. Most of the time, this will mean we send robots due to cost and danger. But sometimes, we will need the irreplaceable judgment and descriptive abilities of a person on the spot.

I always tell the story of 'Irreplaceable.' I initially wrote 'Irreplaceable' with myself in mind, with plans of it being my record. I love that record; however, what I realised about that record was that though given the circumstances of that situation - men and women are not that different - when you sing about it, it changes things, you know?

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