I became famous so quickly and so young - it was daunting. I was immature and I used to say some really stupid things in interviews. I never smiled on stage so I looked really serious, but it was because I hated my teeth and was incredibly nervous.

As an actor, I think it's always important to separate yourself from your characters because, when you include yourself in a character, you're taking a liberty that you don't really have unless you're life is that incredibly close to the character.

The hardest thing to write was explaining what anxiety feels like. Every time I'd try to really write about what it feels like to have an anxiety attack, I would actually have an anxiety attack. It was good material but so incredibly uncomfortable.

I'm not so interested in technology for technology's sake. I don't need incredibly sophisticated climate-control systems. And I'm absolutely amazed at the time people spend exchanging messages; I don't have a lot of time left over for those things.

One of the dilemmas of architecture in general is that there is a Catch-22 - you can't actually get to be commissioned to do certain types of building until you've already built that type of building. So it seems to be incredibly hard to get going.

A lot of things went incredibly well for 'Scrubs': from a ridiculous number of downloads on the iPods, to whenever they issue a new season on DVD it kinda sells out, and we got nominated for an Emmy. To be picked up for six years is all gravy, man.

When it's good, cinema can be one of the most important things in a person's life. A film can be a catalyst for change. You witness this and it is an incredibly spiritual experience that I'd never lived before; well, maybe only in a football match.

Fame and stuff like that is all very cool, but at the end of the day, we're all human beings. Although what I do is incredibly surreal and fun and amazing and I'm really grateful for it, I don't believe my own press release, do you know what I mean?

I grew up with plenty of smart people. They would beat me at chess; they could solve brain teasers before I could, but then they would struggle in algebra. These were incredibly smart people who simply did not have the foundation in math that I had.

Okay, I am happy with the way I look, but I have never, never, ever thought of myself as a 'pretty girl.' Honestly. When I read some of these scripts I'm sent, and they describe the heroine as 'incredibly beautiful,' I wonder why they sent it to me.

Music, first of all, is completely about abstraction, which is exactly what architecture is not. In a way, it has been incredibly constructive to know what true abstraction is. So you don't fall into the trap of thinking that what you do is abstract.

If you listen to the great Beatle records, the earliest ones where the lyrics are incredibly simple. Why are they still beautiful? Well, they're beautifully sung, beautifully played, and the mathematics in them is elegant. They retain their elegance.

I turn to my wife for everything. Her success has never affected her as a person - she's incredibly loyal. We laugh together; we share everything, and she still surprises me. When I saw her in 'Sweet Charity,' I was so proud to say, 'That's my wife.'

I shy away from plot structure that depends on the characters behaving in ways that are going to eventually be explained by their childhood, or by some recent trauma or event. People are incredibly complicated. Who knows why they are the way they are?

When I started to mention to people who know about such things, 'I'm doing this game, 'Portal 2', they got very excited, suddenly. More excited than anything I've ever done before, weirdly. Gamers are incredibly enthusiastic about the stuff they love.

We're always attracted to characters who are people we could identify with and yet are put through incredibly tortured or difficult circumstances - the idea being that you don't really know who you are until you've been tested or suffered in some way.

So much of television is incredibly predictable. You watch the first five minutes and you know where it's going to go. If you can just create an element of surprise in both the storytelling and tone of a show, you're going to be way ahead of the pack.

In the case of 'News Radio,' I loved that show. I loved the actors and the producers, but I was longing very much for something more to sink my teeth into me. I think it was an incredibly smart show, but I found myself on the peripheral of a lot of it.

And of course I've got kids of my own now, and they love me being in the Harry Potter films. I'm now part of a phenomenon. You become incredibly cool to your kids, and you get a young fan base. So you became the cool dad at school. You're suddenly hip.

I have had the most wonderful childhood, and I was raised in a very loving family. And it was nothing short of an amazing privilege because I was incredibly lucky to be able to play up in trees and make it like silly dens in a bush and stuff like that.

I was given a thick paperback copy of the 'Guinness Book of Records' when I was 11 years old, and I read it gluttonously, cover to cover, paying special lip-smacking attention to all the incredibly gruesome chapters about the violence of human history.

I'm looking for best practices constantly. Apple has beautiful design, beautiful product, incredibly functional. But mostly it's about picking product, getting behind it, marketing it and introducing it to a customer. What they've done just inspires me.

I knew from the time I was a young girl that I was destined to be a writer. I'm incredibly stubborn. The more someone tells me I can't do something, the harder I work to prove them wrong. My father's nickname for me when I was growing up was 'Hardhead.'

When we first started 'The Big Bang Theory,' I would get incredibly nervous because it's such a big show and I was just out of graduate school. I'd come in and have this huge responsibility for the one line that everyone hopes will bring down the house.

Just so many special moments that make you feel incredibly fortunate and grateful to be able to have healthy, beautiful kids. And I'm sure the emotions will continue to change over time, and as I get older, I'll probably want to yell and scream at them.

I confess that Roy was a little bit dictatorial in his editing and he ruined quite a number of my pictures, which he stopped doing later. He used to punch a hole through a negative. Some of them were incredibly valuable. He didn't understand at the time.

My way of being with people is probably incredibly unhealthy, in that I'll be incredibly social, and I won't write a word for maybe a year, and I'll just be with people, going to parties and soaking up stories, and just sort of recharging all of my ideas.

Hundreds of people who've never written before send in 'Dr. Who' scripts. They may have good ideas, but what they fail to realise is that writing for TV is incredibly complicated. They have no idea how difficult it is and what the financial commitment is.

I'm the kind of person you want to kill. I had an incredibly happy childhood. I married a terrific guy when I was 23. I have great, well-adjusted kids. Sometimes my husband and I look at each other and do a little jig in the kitchen. This is the best life.

Morocco is such a beautiful place. It's incredibly beautiful. And also it is captivating place because for a writer, you feel that you make impact. I mean, when I write something in the press, the day after in the fish market, people will be discussing it.

The universe is incredibly wondrous, incredibly beautiful, and it fills me with a sense that there is some underlying explanation that we have yet to fully understand. If someone wants to place the word 'God' on those collections of words, it's OK with me.

I've been working on Barb for a while. I looked at her as a sort of every woman. She's incredibly strong; she's incredibly generous. She's seemingly insane because she is in the situation of a polygamous relationship, but she had definite reasons to do it.

Look, if I ever stop being grateful for gigs, I just need to stop. Because this business is... you know, it's just so kind of job-to-job, and the fact that I've continued working... I'm just incredibly thankful for it. And I never, ever take it for granted.

Our initial idea with Stripe was that for people like us - those building apps and websites - it was incredibly difficult to take payments. So with an open mind, and maybe a useful lack of knowledge about the industry, we started building a payment product.

I still dream about that one opportunity where the Welsh Rugby Union call me up and say, 'We need you.' There is an incredibly talented Welsh hooker called Matthew Rees, so maybe some incredible quirk of misfortune for him would mean I get called up instead.

Nobody is accidentally in Alaska. The people who are in Alaska are there because they choose to be, so they've sort of got a real frontier ethic. The people are incredibly friendly, interesting, smart people - but they also stay out of each other's business.

BlogHer is an incredibly important conference because it really taps into the power of women. It gives women an ability to do what they do - take care of the home, go to work - and, at the same time, spread their power through the power of the digital world.

It's incredibly important to me that you remember a song right after the first or second time you hear it. That something sticks to you, something that makes you feel, 'I need to hear that song again.' That's fundamental. Something you want again. And again.

A single neuron in the brain is an incredibly complex machine that even today we don't understand. A single 'neuron' in a neural network is an incredibly simple mathematical function that captures a minuscule fraction of the complexity of a biological neuron.

The fact that I fell in love with Meghan so incredibly quickly was sort of confirmation to me that all the stars were aligned; everything was just perfect. It was this beautiful woman just sort of literally tripped and fell into my life; I fell into her life.

A Christian school should be a place where young men and young women go through a period of spiritual formation and development so that they come out incredibly more proficient at living out their calling than they would have been had they not gone to school.

I'm incredibly grateful to be playing the villain in a world which, if I really thought to hard about what I was doing, I would get very nervous about the size and the magnitude of the importance and responsibility of being a villain in the world of 'Batman.'

I really believe that the movie will never be as good as the book, both because the book goes on longer - a movie is basically an abridgment of a book - and because books are internal. But they are incredibly powerful. The visual format is, you know, amazing.

Archaeology can be overlooked as a discipline, I think, but it's incredibly important to have this other way of approaching the past - not just through historical documents, but through actual physical remains - objects, buildings and the layout of our towns.

You don't have to be singing specifically about things that are going on in your life, but because of the nature of music, because it is this incredibly emotional phenomenon, everything that you are feeling or experiencing is relayed in the music you put out.

My mother's incredibly giving, almost too giving at times. And, my dad is a real logical person. He's got logic for every situation. They've been married for 24 years, so there was that stability, also. I really learned to think on my own at a very young age.

On a more practical level, anyone out there who wants to be a writer should clearly recognize that this is a brutal business, where even incredibly talented people sometimes never make a living. If you want to chase such a dream, please have a Plan B in place.

I think cookies are sort of the unsung sweet, you know? They're incredibly popular. But everybody thinks of cakes and pies and fancier desserts before they think cookies. A plate of cookies is a great way to end dinner and really nice to share at the holidays.

I was so lucky. I grew up with an incredibly strong grandmother, mother and sister. All three, independent, fierce, clever women who were hard workers, had goals and visions for themselves, and were really ambitious. And, they didn't apologize for those goals.

I don't know a single woman in her 40s who isn't incredibly full of life and sexuality and desire for everything. There's nothing sexier than life experience, and there's nothing sexier than knowing your own body and having a little bit of experience with that.

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