I always read about these stories of entrepreneurs - it's like they're in the desert with no water, and they're the ones that survive. But I've been really fortunate to have people on my team who are optimistic about the future and who know that if you work through hard times that there's usually something good at the end.

Ultimately, I think it takes a certain grit and determination to constantly re-prove to people that you're just as dedicated, just as determined, and just as capable as the entrepreneurs around you who may better fit the physical pattern - but on the flipside, women who succeed often become razor sharp through the process.

As always, space remains an unforgiving frontier, and the skies overhead will surely present obstacles and setbacks that must be overcome. But hard challenges demand fresh approaches, and I'm optimistic that Stratolaunch will yield transformative benefits - not only for scientists and space entrepreneurs, but for all of us.

Great entrepreneurs focus intensely on an opportunity where others see nothing. This focus and intensity helps to eliminate wasted effort and distractions. Most companies die from indigestion rather than starvation, i.e., companies suffer from doing too many things at the same time rather than doing too few things very well.

Energy Secretary Ernest Moniz, arguably President Obama's best Cabinet appointment, has been leading a quiet revolution in clean-energy technology. Innovation is transforming this industry, costs are plummeting and entrepreneurs are devising radical new systems that create American jobs - in addition to protecting the planet.

One reason why upturns follow downturns is that downturns tend to overshoot. People get panicky, they're afraid to stay the course, so they start selling. The other thing is that I think, as entrepreneurs keep on waiting to produce new things, that there's an accumulation of as-yet-unexploited new ideas that keeps mounting up.

People of Baltimore, if you want to simply learn a new trade, if you want to join the Foundry, it's a membership. It's like joining a gym, and you can go and meet other entrepreneurs like you. You can talk about how to get financing. You can take a class on how to sew. You can take a class and say, 'I want to be an electrician.'

We had this unbelievable faith that no business has done, quite frankly, and we tripped along the way doing it, but within two years, we were in 40-plus countries. So we ran at an amazing pace, and this is where venture capitalists play a role. Making Groupon into what it is today, we had no role in it; the entrepreneurs did it.

Did Google know much about media? Or Amazon about commerce? Tesla about cars? SpaceX about rockets? EBay about classifieds? What did I know about computing when I started Sun Microsystems? We should celebrate these entrepreneurs, not pillory them for fighting entrenched incumbent industries that have political influence and money.

Often, entrepreneurs don't build a board until they are forced to by their VCs when they raise their first financing round. This is dumb, as you are missing the opportunity to add at least one person to the team who - as a board member - can help you navigate the early process of building your company and raising that first round.

Pirates are the very essence of profit maximising entrepreneurs described in neoclassical economics. Yet, whilst films such as 'The Pirates of the Caribbean' and 'Butch Cassidy and the Sundance Kid' have gone a long way to popularise both pirates and outlaw behaviour, the truth of the matter is that piracy is illegal, and it kills.

Supported by digital data, new data-driven tools, and payment policies that reward improving the quality and value of care, doctors, hospitals, patients, and entrepreneurs across the nation are demonstrating that smarter, better, more accessible, and more proactive care is the best way to improve quality and control health care costs.

We've been prepared to make the arguments for lowering corporation tax, which is all about encouraging risk takers, encouraging entrepreneurs, and I observe that for the vast majority of the Labour government we had a top rate of 40 per cent income tax. It's now higher, and I think we should look to get to a simpler, lower tax system.

The attributes for entrepreneurs cut both ways. You need the ability to ignore inconvenient facts and see the world as it should be and not as it is. This inspires people to take huge leaps of faith. But this blindness to facts can be a liability, too. The characteristics that help entrepreneurs succeed can also lead to their failure.

Artists, writers and people in creative fields are entrepreneurs by necessity. Nobody gives them a paycheck or picks up their medical insurance. The ones who succeed learn to think and act like 'independent operators.' I think people who are technically 'employees' have to think this way as well. The company is not looking out for you.

Those in technology who can afford to stay in Silicon Valley all know it as one of the most beautiful places to live in the world, but a wariness has sunk in as folks from other walks of life are forced to leave: coffee shops are wall-to-wall with aspiring entrepreneurs, and restaurants buzz with talk of valuations and venture capital.

Whether through the introduction of a Universal Basic Income, or through developing ways to ensure that the self-employed, entrepreneurs and fledgling start-up companies have the support they need to take chances and innovate, the £500bn investment programme proposed by Corbyn responds to the challenges we will inevitably have to face.

Investors do not like losing money. They do not like companies that fail. They do not like entrepreneurs that fail. There is not a culture of celebrating failure in Silicon Valley or anyplace else. That is a myth. Recognize this, and if you start another business, get it to a successful point before approaching outside investors again.

For over forty years, I've been one of the most passionate believers in entrepreneurs. From day one, I've learned that too many small businesses are predicated on business models that the owner barely understands, and then, those same men and women are baffled when their business dreams are overwhelmed with struggles they never foresaw.

You know what works in venture capital? A group of incredibly smart, connected people who have the financial wherewithal and risk appetite to make multi-million dollar bets on unproven ideas and inexperienced founders. People who can make decisions quickly, and who spend their time trying to help entrepreneurs make the most of that cash.

Entrepreneurs always begin the journey believing that they have the next big idea. They dream of the fame and fortune that awaits them if only they had the funding to pursue it. But the reality is that as the product is built and shared with customers, flaws in their concept are discovered that - if not overcome - will kill the business.

In 2007, there weren't any other accelerators, at least that I was aware of. We were almost the prototypical Y Combinator founders: We were highly technical but had never done a startup before. We also didn't know anyone in the Valley - investors, other entrepreneurs, potential hires. YC seemed like a great way to bootstrap that network.

We will continue to work with agencies across the government to unleash the power of open data and to make government data more accessible and usable for entrepreneurs, companies, researchers, and citizens everywhere - innovators who can leverage these resources to benefit Americans in a rapidly growing array of exciting and powerful ways.

We would love to see Canadian federal and provincial governments establish a new business entity class like the CIC or L3C for social enterprises. Our governments should also offer tax incentives to entice more entrepreneurs into the social economy, and encourage foundations and impact investors to put their capital into social enterprises.

We are raising today's children in sterile, risk-averse and highly structured environments. In so doing, we are failing to cultivate artists, pioneers and entrepreneurs, and instead cultivating a generation of children who can follow the rules in organized sports games, sit for hours in front of screens and mark bubbles on standardized tests.

There was a study done in the early 20th century of all the entrepreneurs who entered the automobile industry around the same time as Henry Ford; there were something like 500 automotive companies that got funded, had the internal combustion engine, had the technology, and had the vision. Sixty percent of them folded within a couple of years.

The idea that there is one kind of African is, of course, ridiculous. Sometimes African entrepreneurs want to kill you because you are saying public health is the priority, not roads. Of course they are right to press for that issue, but so are we right, I believe, to argue, for example, that millions of children could and should be vaccinated.

Music is one of those businesses in which, if you're talented and hustle hard enough, you can make it - specifically as an entrepreneur. If you look as far back as Berry Gordy, Russell Simmons, Andre Harrell, L.A. Reid, and Sean 'Diddy' Combs, there's a whole lineage of successful black entrepreneurs who have built their own companies from scratch.

Some incubators, like Y Combinator and TechStars, were started by successful entrepreneurs wishing to help the next generation learn from their experiences. Other programs, such as Viterbi Startup Garage and Austin Technology Incubator, were created by universities to help young entrepreneurs bridge the knowledge gap from student to funded company.

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