Quotes of All Topics . Occasions . Authors
That the primary effect of gene mutation may be as simple as the substitution of a single amino acid by another and may lead to profound secondary changes in protein structure and properties has recently been strongly indicated by the work of Ingram on hemoglobin.
I spent lunchtime in a grave during the filming of 'Bloody Mama.' When you're younger, you feel that's what you need to do to help you stay in character. When you get older, you become more confident and less intense about it - and you can achieve the same effect.
What we should notice is that studies show that fathers' presence in their children's lives has a marked effect on how well their kids do later in life, so why aren't we asking how we can better liberate men from the workplace to be home with their kids more often?
One of my earliest memories was watching Ken Patera and Big John Studd cut Andre The Giant's hair. That was the first thing that had a serious effect on me emotionally. I was just moping around the house all day. I couldn't believe they did this to Andre The Giant.
Growing up as a comedian the most influential person on me was Jon Stewart. He showed that comedy could have a real tangible effect on the world. He showed that comedy could move the needle of society and that a comic can do real things and make a real contribution.
The little may contrast with the great, in painting, but cannot be said to be contrary to it. Oppositions of colors contrast; but there are also colors contrary to each other, that is, which produce an ill effect because they shock the eye when brought very near it.
As a child, I felt that Hallowe'en was a time when creatures of the night suddenly came to life - we would turn off all the lights in the house and let flickering candlelight conjure up scary shadows and create the effect of imaginary figures lurking in dark corners.
Visibility has an effect on those who are privileged; it brings more privilege, and on those who are marginalized, it brings more marginalization, because it also brings a spotlight onto them where they're at, in the hood or in certain places that are less tolerable.
We live in a very uncertain world, and I think that uncertainty of itself generates an environment which we should not make a decision that deprives future generations of the deterrent effect that the nuclear weapons have provided for us and for almost all of my life.
Even if the Constitution of the United States had intended to recognize slavery, as a constitutional state institution, such intended recognition would have failed of effect, and been legally void, because slavery then had no constitutional existence to be recognized.
The Vietnamese have a secret weapon. It's their willingness to die beyond our willingness to kill. In effect, they've been saying, You can kill us, but you'll have to kill a lot of us; you may have to kill all of us. And, thank heaven, we are not yet ready to do that.
I guess it could be said that the inspiration for 'Requiem for a Dream' is watching the American dream not only destroy so many lives in the U.S., but infect the rest of the world with its obsession with getting more, ignoring the deadly effect that has on the planet.
A lot of TV can be linear and cinematic and formulaic. What's to say that people can't be creative and surreal - and push boundaries? You can look at a piece of art and not necessarily know what it means or what the artist intended by it. It's the effect it has on you.
I used to listen to Judy Garland all the time - I love Judy Garland and her music. But I started to realize that if you keep singing like that, singing songs of being victimized by love over and over and over again, it can't help but have a profound effect on your life.
It's a wonderful side effect of what we're doing, to give someone the strength to come out of the closet to their family, or simply present themselves aesthetically in a way they feel happy with, whether or not their friends are going to be allowed to like them anymore.
During the Great Depression, African Americans were faced with problems that were not unlike those experienced by the most disadvantaged groups in society. The Great Depression had a leveling effect, and all groups really experienced hard times: poor whites, poor blacks.
In Hong Kong, particularly, we craft this art for decades. The action choreographer actually is the action director. He takes over and he choreographs with - by himself or with his team, and place the camera where he feels cinematic effect to bring out that choreography.
I think there is a complicated side effect to overcoming evil in that we are forever changed by it. I think after we ingest some of the cruelty of the world, it takes years off of our lives, but it also gives us wisdom and a little grace, hopefully a sense of compassion.
It is impossible for Bangladesh alone to take action against the rising sea level, as it has been a cumulative effect of global emission in which Bangladesh does not have any role. It is the responsibility of global community to address this issue as urgently as possible.
President Obama's first term in office has been better for intentions than for actual changes in planning and policy. I do believe, and he has several things to this effect, that he would like to provide universal preschool or at least far more preschool for our children.
We all have friends that we confide in and talk to about our relationships. At times, we do not recognize the effect that this has on our relationship. We take a lot of what other people have to say to heart, and rightly or wrongly, it makes our way into our relationships.
As parents, can we counter the effect of television violence? One worrying feature in Britain is that so many TV sets are in a child's bedroom; this means that the mediating effect of watching with a parent, the ability to discuss and interpret what has been seen, is lost.
Sometimes when I flick through a magazine and see these thin models I'm left wondering what effect they can have on an insecure person. But I say to girls: forget what you see in the magazines, that is a world which has nothing to do with reality; think of it as a cartoon.
My grandfather was a really, really tough no-nonsense factory worker who emigrated from Ireland in about 1900 to Bridgeport, Conn. He had a big effect on me. Those guys who took a great leap out into what they knew not were the ones who were the real stars, the real heroes.
If the brain expects that a treatment will work, it sends healing chemicals into the bloodstream, which facilitates that. And the opposite is equally true and equally powerful: When the brain expects that a therapy will not work, it doesn't. It's called the 'nocebo' effect.
Pre-poll surveys receive different reaction in the media among voters and political parties. For example, the more undecided voters are, the greater the role and effect of pre-poll surveys. Similarly, greater the decline of the party system, the more influential their role.
I won't compare ants and people, but ants give us a useful model of how single members of a community can become so organized that they end up resembling, in effect, one big collective brain. Our own exploding population and communication technology are leading us that way.
I love theater work because of the immediate effect your performance has on the audience. And I love the repetition; I love getting on the same stage for more than a month and reciting the same lines, trying to make a small or large step towards an improvement in my acting.
I am my own man. I governed as a conservative, and I govern effectively. And the net effect was, during my eight years, 1.3 million jobs were created. We left the state better off because I applied conservative principles in a purple state the right way, and people rose up.
In the child, consciousness rises out of the depths of unconscious psychic life, at first like separate islands, which gradually unite to form a 'continent,' a continuous landmass of consciousness. Progressive mental development means, in effect, extension of consciousness.
I suppose I was interested in creating a vision; in the same way, I was very drawn to tension within cinema. Hitchcock was my other early obsession - 'Psycho' and its score. So there was the sense of trying to create an atmosphere: how a sound resonates and makes an effect.
Unless you use the vocoder the way Daft Punk use it, it is very limited. When they sing it's almost human. It sounds sexy. I just used it as an effect. It wasn't because I was not able to sing; I'm not a great singer, but I had some hits as a singer, too. It's a nice effect.
Of all the mediums that influence language, I think film is the one that has the most effect. Not so much from the point of view of pronunciation and grammar. I don't think we pick up very many sounds and grammatical instructions from the films we see - but the catchphrases.
The Internet has allowed a lot of access - people feel entitled to change the ending of games, for example. So there are a lot more voices coming at you all the time, which I think has its effect on creative decision making and possibly makes people more afraid to take risks.
I conceived of an instrument that would create sound without using any mechanical energy, like the conductor of an orchestra. The orchestra plays mechanically, using mechanical energy; the conductor just moves his hands, and his movements have an effect on the music artistry.
It is no wonder that bank capital is regulated. When borrowing and lending is profitable, it is tempting for banks to scale up their operations and to borrow and lend too much in relation to their capital, in effect reducing the effectiveness of the potential capital cushion.
A new principle cannot be put into effect without bringing with it new mistakes. But we may, however, be convinced that the laws of life - to which belongs the law that suffering follows the misuse of freedom - will finally be able to bring everything within its right limits.
I was so in love with books from as early as I remember that it seemed a natural step to want to create them. And so I just wanted to be a writer from a very young age. And I think that the lies were just a natural side effect of me wanting to tell stories and write them down.
There is a growing scientific consensus that animals have emotions and feel pain. This awareness is going to effect change: better treatment of animals in agribusiness, research and our general interaction with them. It will change the way we eat, live and preserve the planet.
It's incredibly fun to play someone that you don't like. It exorcises your own demons in a way. It's cathartic. We all have things that we don't like about ourselves, little things. And I get to amplify those things and put them out there. It's fun and it has a cleansing effect.
I don't think that people are disinterested or uninterested in politics. I think very often they are disengaged from the formal political process. To some extent they are suspicious or even despairing of formal politics as a means to give expression and effect to what they want.
Consider the perverse effect cap and trade has on altruistic actions. Say you decide to buy a small, high-efficiency car. That reduces your emissions, but not your country's. Instead it allows somebody else to buy a bigger S.U.V. - because the total emissions are set by the cap.
Every night, you fight for that standing ovation at the end of the night. And if you do something wrong, the domino effect is chaotic. And you must not allow yourself to make mistakes whatsoever. So in that case, theater, it's fascinating because of the discipline that you need.
If we can take young people who excel at the highest levels, put them on the same kind of pedestal as the all-state basketball player and the all-state football player, and begin to get the same kind of recognition, it will have a profound effect, and we are finding that it does.
My dad was a journalist. One great trip we took was to Israel. We went there and drove through the whole country, and it was pretty incredible. We went to the Philippines and saw the beauty of that country but also what poverty really looks like. That had a profound effect on me.
I think a cyber-terrorism attack is overblown, though the threat exists. I think al Qaeda and other groups are more interested in symbolic terrorism, like what they did to the World Trade Center - suicide bombers or something that really has an effect and is meaningful to people.
If I went to somewhere busy, I wouldn't last very long. I can't go to a museum - I'll last 10 or 15 minutes in a museum. The problem is that when one person asks for a photograph, then someone sees a flash goes off, then everyone else sort of... it's sort of like a domino effect.
There's a cumulative effect to getting good parts as a freelance actor, because you're only as good as your last job, and you have to keep going out and getting them. Unless you're part of the finance structure, by which I mean a bankable star, which I never was and never will be.
I feel connected to the Second World War because my father lost his father in that war. So, through my dad and the effect it had on him of losing his father young, I always felt connected to the war. It goes back years, but it still feels to me as if we're completely living in it.
Lewis Carroll, you see, wasn't really interested in telling an exciting story. Well, he wasn't interested in things like cause and effect or a linear narrative. It's surreal, it's absurd, it's wordplay, it's satirical, it's analyzing itself, it's funny, it's an enormous challenge.