Insecurities are debilitating a lot of times.

Stage fright is a real thing. It's debilitating to some people.

To be sympathetic without discrimination is so very debilitating.

Apparently, blaming oneself for debilitating student debt is common.

When my lips are dry, I can't smile, I can't talk - it's debilitating!

I got my first migraine on my first day of work in TV in 2001... it was debilitating.

Living with mental illness is not a choice and can lead to debilitating circumstances.

I have both sleep apnea and atrial fibrillation, which are both debilitating conditions.

I have had Crohn's for about 19 years. It is a debilitating disease that affects my colon.

No sane man can afford to dispense with debilitating pleasures. No ascetic can be considered reliably sane.

No sane man can afford to dispense with debilitating pleasures; no ascetic can be considered reliably sane.

Gene editing will be used to alter DNA to erase the origins of a range of debilitating inherited disorders.

Breakups are a horrible thing for almost everybody I know. For someone who is a love addict, it's debilitating.

When you are in unrelenting, excruciating and debilitating pain that never goes away for years on end, your life is over.

I had debilitating back pain. Three years later, I'm 40 pounds heavier and generating 20 or 25 miles an hour more ball speed.

I have worked in the federal government and saw the debilitating effects of our antiquated civil service system on morale and results.

The more we know about Lyme, the more we can do to treat patients and educate families to stop the spread of this debilitating disease.

I think the word 'yips' trivialises it; it is completely debilitating, like a cancer spreading through your game and just destroying it.

I personally believe in progress. I think one of the most debilitating and harming things you can do to a child is to keep them in the dark.

When you go through a traumatic event, there's a lot of shame that comes with that. A lot of loss of self-esteem. That can become debilitating.

No one understands the dysfunctions and debilitating impact of America's political system in the swamp better than Mark Melcher and Steve Soukup.

Pride and vanity, the opposites of humility, can destroy our spiritual health as surely as a debilitating disease can destroy our physical health.

I have learned that trying to guess what the boss or the client wants is the most debilitating of all influences in the creation of good advertising.

When life is going to present you with tons of problems - really hard ones, some less hard, some debilitating - it's what you do about them that matters.

I've never really understood people who climb socially by sucking up. It seems like the least efficient way to climb, and also the most psychologically debilitating.

When people age, the main valve carrying blood out of the heart becomes brittle. As this aortic valve narrows, it can cause debilitating heart failure, and even death.

Everyone reaches their point in time where either they die or they get sick of doing drugs. It started getting debilitating. I enjoy my music a lot better than my drugs.

Part of what was in the ether all around me growing up, until I was between 19 and 20, was a terrible, debilitating stutter. It was part of what made me very reclusive as a kid.

Millions of American families affected by debilitating diseases have new hope today after the U.S. House passed legislation to support potentially life-saving stem cell research.

Skyrocketing insurance premiums are debilitating our Nation's health care delivery system and liability insurers are either leaving the market or raising rates to excessive levels.

More important is the fact that embryonic stem cell research could lead to new treatments and cures for the many Americans afflicted with life-threatening and debilitating diseases.

Lyme disease is very debilitating. Being from the East Coast I know Lyme disease is quite common and may lay dormant and may produce flu-like symptoms, as well as neurological issues.

Men and women who have served in harm's way experience higher rates of divorce and suicide. Many battle the debilitating effects and stigma associated with Post Traumatic Stress Disorder.

I can't imagine anything more debilitating, anything more challenging, anything more thrilling than to get on a stage and do any kind of play. It is such a vulnerable place for any actor to be in.

There are so many opportunities in life, that the loss of two or three capabilities is not necessarily debilitating. A handicap can give you the opportunity to focus more on art, writing, or music.

Lyme disease has become a fast epidemic worldwide. I am determined to help find a cure and figure out a way to share knowledge with the millions of people struggling with this debilitating disease.

There is the desire of a consumer society to have no learning curves. This tends to result in very dumbed-down products that are easy to get started on, but are generally worthless and/or debilitating.

Listen, I think that people want a president who is going to be interested in the things that keep them up at night, the things that are weighing on them, the things that are debilitating and can be addressed.

When I went to Everest, I underestimated things. I just didn't know what altitude could do. Or the cold - I especially didn't appreciate the cold. It can be just debilitating, and things can happen so quickly.

I think people who have all kinds of debilitating mobility issues will benefit from robotic augmentation. That is, even before we get into organ replacement and organ printing and synthetic biology and so on and so forth.

Mr. Speaker, the scientific evidence is overwhelming that embryonic stem cells have great potential to regenerate specific types of human tissues, offering hope for millions of Americans suffering from debilitating diseases.

I'm here. I'm not going anywhere. No matter what the injury - unless it's completely debilitating - I'm going to be the same player I've always been. I'll figure it out. I'll make some tweaks, some changes, but I'm still coming.

I'm not the spring chicken everyone wants. I've got a debilitating illness. The brave face is 'I'm busy with work' but I've sort of chucked myself on the scrapheap. That's why I'm single. I've resigned myself to being a difficult woman.

I am pro-choice, but I don't consider that inconsistent at all with pro-life - there's no way that having an abortion, ever, is an easy decision, and it more often errs on the side of absolutely wrenching, not to mention physically debilitating.

People in this room must have back problems, I'm sure some of us do, and it is really, really one of the worst pains and debilitating parts of your body that you can actually have because you really can't do anything in your life when you have it.

There's a reason that there are oodles of young Aussies, Germans, Japanese, even Chinese backpackers traipsing around the world. They are unencumbered by debilitating student loans. No such luck for the American Theater Arts major with $120,000 in loans.

Fear is the most debilitating emotion in the world, and it can keep you from ever truly knowing yourself and others - its adverse effects can no longer be overlooked or underestimated. Fear breeds hatred, and hatred has the power to destroy everything in its path.

I had prostate cancer that, for me, was debilitating. I didn't touch a guitar for two years, but when I realized I was seeing the light at the end of the recovery tunnel and was going to live pain-free, I realized again that it was a fun little instrument to play.

I had a really, really bad case of it. Everybody hears OCD and they think, 'Okay, you like to clean or be organized.' That's really not what it is, especially not for everybody. In my case, it was me being super self-conscious, to the point where it was debilitating.

When my brother died in 1966, my father began a grieving process that lasted almost twenty-five years. For all that time, he suffered from chronic, debilitating headaches. I took him to some of the country's major medical facilities, but no one could cure him of his pain.

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