The hybridoma technology was a by-product of basic research. Its success in practical applications is to a large extent the result of unexpected and unpredictable properties of the method. It thus represents another clear-cut example of the enormous practical impact of an investment in research which might not have been considered commercially worthwhile, or of immediate medical relevance. It resulted from esoteric speculations, for curiosity's sake, only motivated by a desire to understand nature.

The brilliant costume designer Mary Zorphres had done all this research on West Texas in 1980. Every woman looked like that. At a certain age, they would get their hair cut off, let the gray go in, get that permanent, and wear those big glasses. She gave me a beanie bra so my boobs would hang down, and these old dresses. My hat's off to her, because I thought it was perfect for the movie. It was so great to have some comic relief right at that moment. No Country For Old Men is such an intense film.

He had drawn many a thousand of these rations in prisons and camps, and though he'd never had an opportunity to weight them on scales, and although, being a man of timid nature, he knew no way of standing up for his rights, he, like every other prisoner, had discovered long ago that honest weight was never to be found in the bread-cutting. There was short weight in every ration. The only point was how short. So every day you took a look to soothe your soul - today, maybe, they haven't snitched any.

I remember the first day I was looking at my hands and I thought about my nails. People wouldn't really be paying attention to that, but a Civil War doctor - What would they be doing with their nails? Would they cut them really low? And Dr. Burns said, "No, they would let them grow out so they can scoop stuff out. They would use their nails." So for a while I let my nails grow. They were too long. I kept stabbing myself by accident, so I cut them down, but I was trying to be faithful to the details.

I do think that Republicans are flirting with their tax cut, which has always been the narcotic of Republicans, that they in fact have to at some point, with any remote pretense of candor, abandon any pretense of a balanced budget.I mean, they talk about - because they are going to finance the tax cut by tax cuts. That's how they're going to do it. And I do think that the will is there right now in the Congress to act. I think they will be as close to unity as you will see on Capitol Hill this year.

The medieval doctors of divinity who did not pretend to settle how many angels could dance on the point of a needle cut a very poor figure as far as romantic credulity is concerned beside the modern physicists who have settled to the billionth of a millimetre every movement and position in the dance of the electrons. Not for worlds would I question the precise accuracy of these calculations or the existence of electrons (whatever they may be). The fate of Joan is a warning to me against such heresy.

John Carmack, who has become interested in focusing on things other than game development at id, has resigned from the studio. John’s work on id Tech 5 and the technology for the current development work at id is complete, and his departure will not affect any current projects. We are fortunate to have a brilliant group of programmers at id who worked with John and will carry on id’s tradition of making great games with cutting-edge technology. As colleagues of John for many years, we wish him well.

It was not the case that one thing morphed into another, child into woman. You remained the person you were before things happened to you. The person you were when you thought a small cut string could determine the course of a year. You also became the person to whom certain things happened. Who passed into the realm where you no longer questioned the notion of being trapped in one form. You took on that form, that identity, hoped for its recognition from others, hoped someone would love it and you.

I do agree that the science is not settled on this. The idea we would put Americans' economy in jeopardy based on scientific theory that is not settled yet to me is nonsense. Just because you have a group of scientists who stood up and said this is the fact... Galileo got outvoted for a spell. To put Americans' economic future in jeopardy, asking us to cut back in areas that would have monstrous economic impact on this country is not good economics and I would suggest is not necessarily good science.

..this is just like life must be for about 99 percent of the people in the world. You're in this place. There's other people all around you, but they don't understand you and you don't understand them, but people do a lot of pointless babbling anyway. In order to stay alive, you have to spend all day every day doing stupid meaningless work. And the only way to get out of it is to quit, cut loose, take a flyer, and go off into the wicked world, where you will be swallowed up and never heard from again.

Part of writing a novel is being willing to leap into the blackness. You have very little idea, really, of what's going to happen. You have a broad sense, maybe, but it's this rash leap. It's like spelunking. You kind of create the right path for yourself. But, boy, are there so many points at which you think, absolutely, I'm going down the wrong hole here. And I can't get back to the right hole. I'm not going to be able to get this section back to the right hole - so I'm just going to have to cut it.

You find out a lot about yourself through athletics. If you're cut out to be a winner or a failure or a quitter, athletics will bring it out of you. You're always stripping yourself down to the bones of your personality. And sometimes you just get a glimpse of the kind of talent you've been given. Sometimes I run and I don't even feel the effort of running. I don't even feel the ground. I'm just drifting. Incredible feeling. All the agony and frustration, they're all justified by one moment like that.

Mr. Vice President, the most fiscally conservative thing this government has ever done, is to invest massively in the green part of the recovery. Because those green dollars are the hardest working dollars in the history of American politics. That same dollar that is being used to cut energy bills, is also cutting global warming gas emissions, is also cutting unemployment, is also cutting poverty, through retrofits it's also raising the value of homes, is also by cleaning the air, cutting asthma rates.

Desire means you are dragged out of the moment; that creates a tension, that creates anxiety, that creates hope. And then finally hope turns sour, becomes frustration. Each hope leads you into anguish. Buddha calls it the only impurity. Cut the roots of desire, live in the moment so totally, pull yourself out of the past and don`t project yourself into the future. Let this moment be all and all. And your life will have such a purity, such a crystal-clear consciousness that right now you cannot imagine.

When we look at cutting people's commute - like that word infrastructure is boring. Who knows what that means? But what it really means is we got to cut people's commutes, we got to reduce congestion. Congestion costs the economy tens of billions of dollars a year to have people just stuck in traffic and non-productive time. So we got to fix that. And the best way to do that is invest in transit. And - so I'm happy that all three of the main parties seem to agree that investing in transit is important.

Passion is what makes life interesting, what ignites our soul, fuels our love and carries our friendships, stimulates our intellect, and pushes our limits... A passion for life is contagious and uplifting. Passion cuts both ways... Those that make you feel on top of the world are equally able to turn it upside down... In my life I want to create passion in my own life and with those I care for. I want to feel, experience and live every emotion. I will suffer through the bad for the heights of the good.

The white youth of today have begun to react to the fact that the American Way of Life is a fossil of history. What do they care if their old baldheaded and crew-cut elders don't dig their caveman mops? They couldn't care less about the old, stiff-assed honkies who don't like their new dances: Frog, Monkey, Jerk, Swim, Watusi. All they know is that it feels good to swing to way-out body-rhythms instead of dragging across the dance floor like zombies to the dead beat of mind-smothered Mickey Mouse music.

In a changing world, some jobs disappear and new ones are created. That's how it has been for hundreds of years. When jobs disappear, the vast majority is not because of global trade, but because of technical advances, robotization and so on. So, we - and in particular, EU member states - have to invest more in training and education so that people will have new opportunities if their jobs are cut. The EU can also better utilize its investment and social funds to protect its citizens from swift changes.

The god which the vast majority of professing Christians love is looked upon very much like an indulgent old man, who himself has no relish for folly, but leniently winks at the indiscretions of youth...For one sin God banished our first parents from Eden; for one sin all the posterity of Canaan fell under a curse which remains over them to this day; for one sin Moses was excluded form the promised land; Elisha’s servant smitten with leprosy; Ananias and Sapphira were cut off from the land of the living.

I was crying and laughing, snuffing tears and blood, bumping at him with my bound hands, trying awkwardly to thrust them at him so that he could cut the rope. He quit grappling, and clutched me so hard against him that I yelped in pain as my face was pressed against his plaid. He was saying something else, urgently, but I couldn’t manage to translate it. Energy pulsed through him, hot and violent, like the current in a live wire, and I vaguely realized that he was still almost berserk; he had no English.

People talking about politics usually start from the ass end backwards in that they think you have a political agenda, and then you make your work fit that cookie cutter. It's the other way around. One works by simple observation, looking into things. It's usually called insight and out of that comes your view - not that you have the view first and then squash everything to make it fit. I'm not interested in cutting the feet off my characters or stretching them to make them fit my certain political view.

Our practical choice is not between a tax-cut deficit and a budgetary surplus. It is between two kinds of deficits: a chronic deficit of inertia, as the unwanted result of inadequate revenues and a restricted economy; or a temporary deficit of transition, resulting from a tax cut designed to boost the economy, increase tax revenues, and achieve -- and I believe this can be done -- a budget surplus. The first type of deficit is a sign of waste and weakness; the second reflects an investment in the future.

Sadly enough, there is a kind of an anti-intellectualism among many Christians: spirituality is falsely pitted against intellectual comprehension as though they stood in a dichotomy. Such anti-intellectualism cuts away at the very heart of the Christian message. Of course, there is a false intellectualism which does destroy the work of the Holy Spirit. But it does not arise when men wrestle honestly with honest questions and then see that the Bible has the answers. This does not oppose true spirituality.

Pulling out his daggers, he kept them in his sleeves, just in case he happened upon someone who wouldn’t understand why a tall, dark-haired man wearing really dark sunglasses and unseasonably warm clothing would be armed to his fangs. Really, Officer, I was trying to protect humanity by killing these things that suck human souls out to live past their twenty-seventh birthday just didn’t cut it. Why no one would believe that, he couldn’t imagine. Really, the audacity of modern courts and judges.’ – Sundown

What a position of transcendent horror must that be, where the perpetrator of a great crime, till then a stranger to positive guilt, finds himself suddenly cut off, and forever, from all human sympathy, isolated from hope, the tenant of a solitary cell, and with a wide, impassable gulf yawning between him and that great brotherhood of which he has ceased to be a part--no longer regarded as a man, but as a monster in the shape of one, from whom Mercy herself turns away, and for whom Pity even has no tears!

When I devoted myself to poetry - and poetry is a very serious medium - I don't think the people that knew me as an individual with that tongue-in-cheek kind of humor...well, it didn't always lend itself to my poetry. When you're writing poetry, it's like working with gold, you can't waste anything. You have to be very economical with each word you're going to select. But when you're writing fiction, you can just go on and on; you can be more playful. My editor's main task is to cut back, not ask for more.

The normal way of gathering information is through sound: when you hear information that you want to gather, you look in its direction, you see what it is, if you choose you can get closer, you can see it, you can touch, and then, finally, the most committed form of data gathering is to taste it and eat it. But for the urbanite, we're cut off from our primary sense, and I want to stress that - our primary sense of gathering information about the place that we're living in - and instead, we're in a war zone.

It has the property of detonating very violently in certain circumstances. On one occasion a small amount of ether solution of pyroglycerin condensed in a glass bowl. ... When the bowl was heated over a spirit lamp, an extremely violent explosion occurred, which shattered it into small fragments. On another occasion a drop was heated in a test-tube, and exploded with such violence that the glass splinters cut deep into my face and hands, and hurt other people who were standing some distance off in the room.

At any given time, on our band Drive-by Truckers' shows there might be someone who's eight years old or 80 years old in the audience. Some nights there are a lot of girls in the audience, some nights not. It's so unpredictable, but I like that. A lot of Republicans come see us. I've got many friends and family that are Republicans, so our following definitely cuts across the political lines and all of that. Which puts us in the unique position of not just preaching to the converted. I respect and value that.

I served as Chairman of the Intelligence Committee. Let me tell you, it's tough to find out what the CIA is doing. They led us astray on the weapons of mass destruction that they said Saddam Hussein found. We sent out Collin Powell, Secretary of State, former National Security Counselor, chief of staff, four star general, couldn't find it out. I'd be reluctant to cut into term limits. I think if the voters would become informed and aroused, they could impose the proper limits on the guys who ought to be out.

There were no men in this painting, but it was about men, the kind who caused women to fall. I did not ascribe any intentions to these men. They were like the weather, they didn't have a mind. They merely drenched you or struck you like lightning and moved on, mindless as blizzards. Or they were like rocks, a line of sharp slippery rocks with jagged edges. You could walk with care along between the rocks, picking your steps, and if you slipped you'd fall and cut yourself, but it was no use blaming the rocks.

You know in politics you are dealing in the realm of choices. You don't always have clear-cut decision between a thoroughly principled position and a thoroughly unprincipled one. You're making snap decisions with paucity of information, generally trying to do the best that you can, but you will make errors, and sometimes it's a decision between a bad and a worse alternative. It has to be done, because we need to order our society, and of politics it can literally be said: Bad job, but someone's got to do it.

Now when you cut a forest, an ancient forest in particular, you are not just removing a lot of big trees and a few birds fluttering around in the canopy. You are drastically imperiling a vast array of species within a few square miles of you. The number of these species may go to tens of thousands. Many of them are still unknown to science, and science has not yet discovered the key role undoubtedly played in the maintenance of that ecosystem, as in the case of fungi, microorganisms, and many of the insects.

I wanted to go higher than Rockefeller Center, which was being erected across the street from Saks Fifth Avenue and was going to cut off my view of the sky. . . . Flying got into my soul instantly but the answer as to why must be found somewhere back in the mystic maze of my birth and childhood and the circumstances of my earlier life. Whatever I am is elemental and the beginnings of it all have their roots in Sawdust Road. I might have been born in a hovel, but I determined to travel with the wind and stars.

[Robert Gottlieb] wouldn't have published 'Remembering Denny' . Denny was a Rhodes Scholar. He was on the swimming team. Had this great California crew cut and this great smile. Life magazine covered his graduation, and Alfred Eisenstaedt photographed it. We all expected him to be president some day. But he committed suicide when he was in his 50s. If he were gay in the 1950s, then the rest of what I wrote was commentary because life was so miserable for gay men back then. And that's why he committed suicide.

I always thought the editor should cut the film and so I'll come in and look at the movie. Just because that's the only way I can really see the ideas of the editor, it's really working together. Yes it's a hierarchy, yes I'm the boss, but I like to see and to think about the idea, and it's about us asking, 'do we have to say that?' and, 'how do we make it there?' So it's advising the editor, it's very give and take, it's very free, but in the end, it's wonderful once you get through the first couple of cuts.

In ancient times, people weren't just male or female, but one of three types: male/male, male/female, female/female. In other words, each person was made out of the components of two people. Everyone was happy with this arrangement and never really gave it much a thought. But then God took a knife and cut everybody in half, right down the middle. So after that the world was divided just into male and female, the upshot being that people spend their time running around trying to locate their missing other half.

It always comes back to our insecurities, as we say, "Oh, I'm not as good as you." So instead of accepting that perhaps I am not as good as someone else in some ways and being comfortable with who I am as I am, I spend all my time denigrating you, trying to cut you down to my self-perceived size. The sad problem is that we see ourselves as being quite terribly small. Instead of spending my time being envious, I need to celebrate your and my different gifts, even if mine are perhaps less spectacular than yours.

The church isn't simply a collection of isolated individuals ... we need to learn again the lesson that a hand is no less a hand for being part of a larger whole, an entire body. The foot is not diminished in its freedom to be a foot by being part of a body which also contains eyes and ears. In fact, hands and feet are most free to be themselves when they coordinate properly with eyes, ears, and everything else. Cutting them off in an effort to make them truly free, truly themselves, would be truly disastrous.

Figure out what you want, how you want to feel, whatever your motivation is, you have to figure it out. That's step one: where do you want to be? The next thing is just trying to get there and cutting yourself some slack along the way. You're going to have days when you veer off your path, then just get right back on. We all have cheat days, holidays, or celebrations, whatever or period when we can't work out as much as we like, and just do the best you can and when you can get back on track, get back on track.

My mom was a housewife, and wasn't somebody that people would think of as a feminist, and when Ms. Magazine came out we were incredibly inspired by it. I used to cut pictures out of it and make posters that said, "Girls can do anything", and stuff like that, and my mom was inspired to work at a basement of a church doing anti-domestic violence work. Then she took me to the Soidarity Day thing, and it was the first time I had ever been in a big crowd of women yelling, and it really made me want to do it forever.

Do the things you used to talk about doing but never did. Know when to let go and when to hold on tight. Stop rushing. Don't be intimidated to say it like it is. Stop apologizing all the time. Learn to say no, so your yes has some oomph. Spend time with the friends who lift you up, and cut loose the ones who bring you down. Stop giving your power away. Be more concerned with being interested than being interesting. Be old enough to appreciate your freedom, and young enough to enjoy it. Finally know who you are.

I'm very, very specific about sneakers. I've always been a fan. It's not just certain brands, it's also the model of the shoe, the cut of the shoe, the colorway of the shoe. Someone will say, "Hey, this is the Air Jordan this." And I'm like, "Yeah, but that's not as rare as this Air Jordan, in this colorway." It gets very specific - it's the make, the model, the colorway. As a kid, I always wanted to have sneakers, but I didn't always get the ones that I wanted. So now, I'm reliving my childhood through my feet.

I do not make films which are prescriptive, and I do not make films that are conclusive. You do not walk out of my films with a clear feeling about what is right and wrong. They're ambivalent. You walk away with work to do. My films are a sort of investigation. They ask questions . . .. Sometimes I hear that some [Hollywood] studio is interested in me. Then they discover that this is the guy who works with no script, that there is no casting discussion, no interference, that I have the final cut, and that does it.

How ignorant we are! How ignorant everyone is! We can cut across only a small area of the appallingly expanding fields of knowledge. No human being can know more than a tiny fraction of the whole. It must have been satisfactory in ancient times when one's own land seemed to be the universe; when research studies, pamphlets, books did not issue in endless flow; when laboratories and scientists were not so rapidly pushing back frontiers of knowledge that the process of unlearning the old left you gasping for breath.

The United States of American business pays the second-highest business taxes in the world, 35 percent. Ireland pays 11 percent. Now, if you're a business person, and you can locate any place in the world, then, obviously, if you go to the country where it's 11 percent tax versus 35 percent, you're going to be able to create jobs, increase your business, make more investment, et cetera. I want to cut that business tax. I want to cut it so that businesses will remain in the United States of America and create jobs.

I saved $725 million on the 90 planes. Just 90. Now there are 3,000 planes that are going to be ordered. On 90 planes I saved $725 million. It's actually a little bit more than that, but it's $725 million. Gen. Mattis, who had to sign the deal when it came to his office, said, "I've never seen anything like this in my life." We went from a company that wanted more money for the planes to a company that cut. And the reason they cut - same planes, same everything - was because of me. I mean, because that's what I do.

Christians, of all people, should not be destroyers. We should treat nature with an overwhelming respect. We may cut down a tree to build a house, or to make a fire to keep the family warm. But we should not cut down the tree just to cut down the tree. We may, if necessary, bark the cork tree in order to have the use of the bark. But what we should not do is to bark the tree simply for the sake of doing so, and let it dry and stand there a dead skeleton in the wind. To do so is not to treat the tree with integrity.

Panic. You open your mouth. Open it so wide your jaws creak. You order your lungs to draw air, NOW, you need air, need it NOW. But your airways ignore you. They collapse, tighten, squeeze, and suddenly you're breaithing through a drinking straw. Your mouth closes and your lips purse and all you can manage is a croak. Your hands wriggle and shake. Somewhere a dam has cracked open and a flood of cold sweat spills, drenches your body. You want to scream. You would if you could. Cut you have to breathe to scream. Panic.

J_Doe032692 wrote: I am not a thin person. However this does not give people the right to taunt me, calling me ugly and worthless, telling me to kill myself because no one will ever want me, or to make up songs about why I am so fat and how much food I eat. NO ONE, I repeat, NO ONE HAS THE RIGHT TO HURT ANOTHER HUMAN BEING THIS BADLY. My throat constricts. The neck brace feels as if it's shrinking and cutting off my esophagus. I reach up and cover the words with my hand and the web site dissolves. I want to go. Now.

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