From an early age, I knew I would become a scientist. It may have been my brother Sam's doing. He interested me in the laws of falling bodies when I was ten and helped my father equip a basement chemistry lab for me when I was fifteen. I became skilled in the synthesis of selenium halides.

I've got to sing for Pops; I've got to keep my father's legacy alive because he started all of this. So I started calling people, and nobody would give me a chance, but I didn't let that stop me. I took money out the bank and I started making me a record, and I did it in this guy's basement.

Once we went into the basement and learned a song, we felt successful. Then we learned two songs, and then we got a gig, and on and on - and that's the way musicians think. I don't know about other people - I mean, I don't know about all musicians either - but some are more driven than others.

I think I have femininity, I have masculinity, but I get to use all of Jeffrey, and that's very powerful. And this is what I always thought when I went down in my little basement in San Francisco, where I grew up, and daydreamed about being an actor: It felt like this. This is what it felt like.

I just played at a club in L.A. called the Baked Potato. It fits like 90 people. It's like playing somewhere in a basement in, like, Indiana or somewhere where all your friends show up. It's really fun and there's a very different energy to that than to play to 50,000 at a Tokyo baseball stadium.

Whenever I approach a record, I don't really have a science to it. I approach every record differently. First record was in a home studio. Second record was a live record. Third record was made while I was on tour. Fourth record was made over the course of, like, two years in David Kahn's basement.

My first time performing was in the black box theater of my high school's basement as a member of 'Clownaz,' the school's improv team. We charged money for tickets, saying the proceeds went to our school's recycling program. Then, immediately after the show, we divided up all the money and kept it.

When I graduated high school, nearly a half-million people subscribed to 'Popular Electronics' magazine. Soldering up some radio or hi-fi amplifier on the basement workbench was not just a personal passion - a lot of young people were doing the same. The magazine expired in 1999 for lack of interest.

The best movie theater in the world is in a dingy basement on Manhattan's Upper West Side. The worn seats are painful. There are probably bigger screens in half the apartments in the complex above the theater. And forget Fandango; the theater barely has a website. You want to buy a ticket? Get in line.

People get TV deals by doing something in their grandmother's basement. It is definitely the wave. Everybody is trying to do all that stuff. I mean, the Internet is the only reason that I've gotten work is because I've somehow created a line and people have seen it. And then I've been asked to auditions.

Ever since I was 7 years old, I was writing. I remember being in the basement of my house, this dank, horrible basement, putting on plays with not-very-willing participants, and I would promise kids in the neighborhood that I'd play Nintendo 64 with them after we'd rehearse this stupid play that I wrote.

The 'International Style of Modernism' came with the advent of building services. In the end, the architecture became like a container space, essentially like a boring box with a basement full of machinery to make it inhabitable. As a result, buildings literally started to look identical all over the planet.

Young actors ask me for advice. They say, 'Should I get an agent?' I tell them, 'Don't worry about that. Act, act, act. Get into that production of 'The Three Sisters' in a church basement. Consider every audition a chance to act, even if it's just for three minutes. Just do it whenever and wherever you can.'

I was writing full time after quitting a job as a high school English teacher, and I hadn't been able to sell anything, and my bank account was down to zero, and all of my friends were like 'What are you doing in the basement, when are you going to get a real job?', and my parents thought I'd completely lost it.

I started playing music around 13 or 14, played jazz in high school, and played other stuff in college. After college, I tried to make it as a musician. I lived in a big squalid house full of dudes outside of Boston. We were all musicians. We built this studio in the basement and played there all hours of the day.

Impulse decisions can often be our downfall when it comes to sticking to good habits. Do something to buy yourself some time when you're experiencing those 'moments' of weakness, and often, the urge will pass. If you keep the cookies in a box in the basement, you might find it's not worth the effort to go get them.

I'm always working on new songs. With the technology these days, any idiot can record on Pro Tools on your laptop. All you have to do is plug a microphone into the input jack and anybody can have their own recording studio. So I'm always down in my basement, singing along to riffs or whoever I'm collaborating with.

As we have seen, WikiLeaks is a robust organization. During my time in solitary confinement in the basement of a Victorian prison, we continue to release, our media partners continued to write stories. The important revelations from this material continue to come out. We have approximately 2,000 cables into 250,000.

Now that our kids are getting older, they need their space. We dug out the basement so they will have a place to go crazy in the wintertime. My son is already talking about how he's going to make a skateboard ramp. It's just a mosh pit down there, so they can do whatever they want. We're not even going to finish it.

In one week, I went from being a girl who owed a guy thousands of dollars - my manager Anthony was paying for my outfits, paying for my food; I was sleeping in his parents' basement - to taking meetings with every major label in America. The next morning, I had a record deal and wrote him a cheque to pay back all that money.

Sidney Farber was a pathologist. He was called a doctor of the dead. He was a pathologist who sort of lived in the basement of the children's hospital in Boston, and he became very interested in childhood leukemia. And Farber began to inject this drug, aminopterin, into young kids, in order to see if he could get a remission.

One of the things I love about working with my brother is that there's a commitment there - an unwavering commitment. From our basement in Illinois when I was three years old to Iceland on a frozen glacier with Matthew McConaughey and Matt Damon in spacesuits - there's a commitment to the pure spectacle, the pure cinema of it.

When I started Virgin from a basement in west London, there was no great plan or strategy. I didn't set out to build a business empire... For me, building a business is all about doing something to be proud of, bringing talented people together and creating something that's going to make a real difference to other people's lives.

It's not the music you hear in your head that other people are going to hear. You have to be able to make it true enough to the image in your head, and that's where technique and technology come in, for sure, and knowledge. It's not true and will never be true that someone who knows nothing can sit in a basement and make great music.

You're just these kids from a small town. You get a record deal, and everything just goes so fast. In the span of five albums... in a way, the band that you started in your bedroom, or your basement or your garage, kind of becomes not your band anymore. It becomes something bigger than you could have known. No one really prepares you.

My mother took my brother and I to a production of 'The Tempest', and it was in this very small - it could have been the basement of a church or a black box. The space was vast, but there were maybe 15 seats in the middle. Ariel came out wearing a nude sparkly thong and spike heels, and the muses had these gossamer see-through gowns on.

In the '80s, society created a caricature of what a hacker or a programmer looked like: a guy wearing a hoodie, drinking energy drinks, sitting in a basement somewhere coding. Today, programmers look like the men we see in the show 'Silicon Valley' on HBO. If you look at the message girls are getting, it's saying, 'This is not for you.'

Pay attention to your friends; pay attention to that cousin that jumps up on the picnic table at the family reunion and goes a little too 'nutty,' you know what I mean? Pay attention to that aunt that's down in the basement that never comes upstairs. We have to pay attention to our friends, pay attention to your family, and offer a hand.

When you're writing a novel, you spend four years sitting in your basement and a year waiting for the book to come out and then you get the feedback. When you do work online, the moment you're finished making it, people start responding to it which is really fun and allows for a kind of community development you just can't have in novels.

It doesn't sound that cool to say it, but I still get nervous for any show. But it's different degrees - playing a small basement of a club versus playing a festival like Firefly or Bonnaroo. The feeling is, 'Crap, I'm about to be blasted in the face,' and once you get started, then it's like, 'OK, I've done this before. I know what I'm doing.'

'Dungeons and Dragons' has evolved over the years, and so has the community that played the game. It had a lot of lingering stigma from the anti-'D&D' movement of the '70s and '80s - this kind of idea that 'Dungeons and Dragons' is only played by the lowest of the low basement dwellers - that has kept people from being comfortable talking about it.

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