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Exercise is very important, first of all if you think about it, especially in a long flight like a six month space flight and on the ISS. If you didn't exercise and used the analogy on earth, it would be like laying in bed. So, just imagine laying in bed for several months, and even just trying to get up and walk, you probably wouldn't be able to. But if you got up and you exercised two hours a day, you'd probably be okay, and that's the same in space.