Since the fabric of the universe is most perfect and the work of a most wise Creator, nothing at all takes place in the universe in which some rule of maximum or minimum does not appear ... there is absolutely no doubt that every affect in the universe can be explained satisfactorily from final causes, by the aid of the method of maxima and minima, as it can be from the effective causes themselves ... Of course, when the effective causes are too obscure, but the final causes are readily ascertained, the problem is commonly solved by the indirect method.