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The hybridoma technology was a by-product of basic research. Its success in practical applications is to a large extent the result of unexpected and unpredictable properties of the method. It thus represents another clear-cut example of the enormous practical impact of an investment in research which might not have been considered commercially worthwhile, or of immediate medical relevance. It resulted from esoteric speculations, for curiosity's sake, only motivated by a desire to understand nature.
