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Depression is about anger, it's about anxiety, it's about character and heredity. But it is also about something that is in its way quite unique. It is the illness of identity, it is the illness of those who do not know where they fit, who lose faith in the myths they have so painstakingly created for themselves. It is a plague - especially if you add in its various forms of expression, like alcoholism, anorexia, bulimia, drug addiction, compulsive behavior of one kind or another. They're all the same things: attempts to avoid disappearance, or nothingness, or chaos.
