Through the discovery of Buchner, Biology was relieved of another fragment of mysticism. The splitting up of sugar into CO2 and alcohol is no more the effect of a 'vital principle' than the splitting up of cane sugar by invertase. The history of this problem is instructive, as it warns us against considering problems as beyond our reach because they have not yet found their solution.

A discussion between Haldane and a friend began to take a predictable turn. The friend said with a sigh, 'It's no use going on. I know what you will say next, and I know what you will do next.' The distinguished scientist promptly sat down on the floor, turned two back somersaults, and returned to his seat. 'There,' he said with a smile. 'That's to prove that you're not always right.'

I really see no harm which can come of giving our children a little knowledge of physiology. ... The instruction must be real, based upon observation, eked out by good explanatory diagrams and models, and conveyed by a teacher whose own knowledge has been acquired by a study of the facts; and not the mere catechismal parrot-work which too often usurps the place of elementary teaching.

I am not afraid of the priests in the long-run. Scientific method is the white ant which will slowly but surely destroy their fortifications. And the importance of scientific method in modern practical life--always growing and increasing--is the guarantee for the gradual emancipation of the ignorant upper and lower classes, the former of whom especially are the strength of the priests.

My final word, before I'm done, Is "Cancer can be rather fun"- Provided one confronts the tumour with a sufficient sense of humour. I know that cancer often kills, But so do cars and sleeping pills; And it can hurt till one sweats, So can bad teeth and unpaid debts. A spot of laughter, I am sure, Often accelerates one's cure; So let us patients do our bit To help the surgeons make us fit.

If you go from the USA - which, relative to the rest of the world, is in pretty good shape in terms of biodiversity and sustainability - to the tropics, everything gets worse. You have Indonesia, which is destroying its own forest. In West Africa there's no control whatsoever. It's a global situation. For that reason it ties in clearly with the needs and relationships of low-income countries.

Most people believe they know how they themselves think, how others think too, and even how institutions evolve. But they are wrong. Their understanding is based on folk psychology, the grasp of human nature by common sense ¾ defined (by Einstein) as everything learned to the age of 18 ¾ shot through with misconceptions, and only slightly advanced over ideas employed by the Greek philosophers

Yes, the natural sciences are telling us a great deal about human origins, the origins of our species the origins of our minds; we're on our way to explaining a large part of it. I'll accept an answer provided only by such means as obtaining and exploring, analyzing and arguing over the evidence - not because of a scribe's myopic view of the subject written 500 years before the birth of Christ!

Chance alone is at the source of every innovaton, of all creation in the biosphere. Pure chance, only chance, absolute but blind liberty is at the root of the prodigious edifice that is evolution... It today is the sole conceivable hypothesis, the only one that squares with observed and tested fact. Stating life began by the chance collision of particles of nucleic acid in the "prebiotic soup."

The students of biodiversity, the ones we most need in science today, have an enormous task ahead of molecular biology and the medical scientists. Studying model species is a great idea, but we need to combine that with biodiversity studies and have those properly supported because of the contribution they can make to conservation biology, to agrobiology, to the attainment of a sustainable world.

The vast results obtained by Science are won by no mystical faculties, by no mental processes other than those which are practicedby every one of us, in the humblest and meanest affairs of life. A detective policeman discovers a burglar from the marks made by his shoe, by a mental process identical with that by which Cuvier restored the extinct animals of Montmartre from fragments of their bones.

Quantitative work shows clearly that natural selection is a reality, and that, among other things, it selects Mendelian genes, which are known to be distributed at random through wild populations, and to follow the laws of chance in their distribution to offspring. In other words, they are an agency producing variation of the kind which Darwin postulated as the raw material on which selection acts.

We are all musicians in a great human orchestra, and it is now time to play the Save the World Symphony. You are not required to play a solo, but you are required to know what instrument you hold and play it as well as you can. You are required to find your place in the score. What we love we must protect. That’s what love means. From the right to know and the duty to inquire flows the obligation to act.

The only objections that have occurred to me are, 1st that you have loaded yourself with an unnecessary difficulty in adopting Natura non facit saltum so unreservedly. . . . And 2nd, it is not clear to me why, if continual physical conditions are of so little moment as you suppose, variation should occur at all. However, I must read the book two or three times more before I presume to begin picking holes.

Today [the voice of women] is being heard loud and clear. But I do not read the welcome triumph of feminism, social, economic, and creative, as a brief for postmodernism. The advance, while opening new avenues of expression and liberating deep pools of talent, has not exploded human nature into little pieces. Instead, it has set the stage for a fuller exploration of the universal traits that unite humanity.

I think what drives scientists is this tremendous intellectual adventure - pushing the boundaries of knowledge, walking down a track that nobody has walked down before, not knowing what's around the corner and then seeing a landscape that is so extraordinarily beautiful and complex, being part of the community that is driving the boundaries of knowledge and giving us insight into the amazing process of life.

The environmental crisis is somber evidence of an insidious fraud hidden in the vaunted productivity and wealth of modern, technology-based society. This wealth has been gained by rapid short-term exploitation of the environmental system, but it has blindly accumulated a debt to nature-a debt so large and so pervasive that in the next generation it may, if unpaid, wipe out most of the wealth it has gained us.

Humanity today is like a waking dreamer, caught between the fantasies of sleep and the chaos of the real world. The mind seeks but cannot find the precise place and hour. We have created a Star Wars civilization, with Stone Age emotions, medieval institutions, and godlike technology. We thrash about. We are terribly confused by the mere fact of our existence, and a danger to ourselves and to the rest of life.

All interpretations made by a scientist are hypotheses, and all hypotheses are tentative. They must forever be tested and they must be revised if found to be unsatisfactory. Hence, a change of mind in a scientist, and particularly in a great scientist, is not only not a sign of weakness but rather evidence for continuing attention to the respective problem and an ability to test the hypothesis again and again.

Perhaps the simplest example is a synthetic plastic, which unlike natural materials, is not degraded by biological decay. It therefore persists as rubbish or is burned-in both cases causing pollution. In the same way, a substance such as DDT or lead, which plays no role in the chemistry of life and interferes with the actions of substances that do, is bound to cause ecological damage if sufficiently concentrated.

The naturalist is a civilized hunter. He goes alone into the field or woodland and closes his mind to everything but that time and place, so that life around him presses in on all the senses and small details grow in significance. He begins the scanning search for which cognition was engineered. His mind becomes unfocused, it focuses on everything, no longer directed toward any ordinary task or social pleasantry.

The paradox is that, by children taking shortcuts through computer games, through fantasies, through movies that load on all the emotional stimulation of encountering life in a stylized way - all of this is the equivalent of mainlining of paleolithic emotions, emotions about combat, about personal success, about overcoming monsters, about making powerful friendships, about winning wars and entering new territory.

Insect resistance to a pesticide was first reported in 1947 for the Housefly (Musca domestica) with respect to DDT. Since then resistance to one or more pesticides has been reported in at least 225 species of insects and other arthropods. The genetic variants required for resistance to the most diverse kinds of pesticides were apparently present in every one of the populations exposed to these man-made compounds.

The big question that scientists haven't even begun to get an answer for is how many species of microorganisms are there? Now, this is not stamp collecting. What we need is experts totally devoting their research to everything they can find out about every species, in a community of scientists who appreciate that every fact counts...everything new you learn about any species in any group is worth publishing somewhere.

I have endeavoured to show that no absolute structural line of demarcation, wider than that between the animals which immediately succeed us in the scale, can be drawn between the animal world and ourselves; and I may add the expression of my belief that the attempt to draw a physical distinction is equally futile, and that even the highest faculties of feeling and of intellect begin to germinate in lower forms of life.

Agnosticism, in fact, is not a creed, but a method, the essence of which lies in the rigorous application of a single principle. ... Positively the principle may be expressed: In matters of the intellect, follow your reason as far as it will take you, without regard to any other consideration. And negatively: In matters of the intellect, do not pretend that conclusions are certain which are not demonstrated or demonstrable.

By 2050, at bio-extinction's current rate, between 25 per cent and 50 per cent of all species will have disappeared or be too few in numbers to survive. There'll be a few over-visited parks, the coral reefs will be beaten up, grasslands overgrazed. Vast areas of the tropics that have lost their forests will have the same damn weeds, bushes and scrawny eucalyptus trees so that you don't know if you're in Africa or the Americas.

Humanity is a biological species, living in a biological environment, because like all species, we are exquisitely adapted in everything: from our behavior, to our genetics, to our physiology, to that particular environment in which we live. The earth is our home. Unless we preserve the rest of life, as a sacred duty, we will be endangering ourselves by destroying the home in which we evolved, and on which we completely depend.

Next to being right in this world, the best of all things is to be clearly and definitely wrong, because you will come out somewhere. If you go buzzing about between right and wrong, vibrating and fluctuating, you come out nowhere; but if you are absolutely and thoroughly and persistently wrong, you must, some of these days, have the extreme good fortune of knocking your head against a fact, and that sets you all straight again.

For these two years I have been gravitating towards your doctrines, and since the publication of your primula paper with accelerated velocity. By about this time next year I expect to have shot past you, and to find you pitching into me for being more Darwinian than yourself. However, you have set me going, and must just take the consequences, for I warn you I will stop at no point so long as clear reasoning will take me further.

It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body. The time may come when penicillin can be bought by anyone in the shops. Then there is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.

Perhaps one of the most meaningful ways to sense the impact of the environmental crisis is to confront the question which is always asked about Lake Erie: how can we restore it? I believe the only valid answer is that no one knows. For it should be clear that even if overnight all of the pollutants now pouring into Lake Erie were stopped, there would still remain the problem of the accumulated mass of pollutants in the lake bottom.

It is ordinarily said that criminal law is designed to protect property and to protect persons, and if society's only interest in controlling sex behavior were to protect persons, then the criminal codes concerned with assault and battery should provide adequate protection. The fact that there is a body of sex laws which is apart from the laws protecting persons is evidence of their distinct function, namely that of protecting custom.

Small-scale fisheries should not be favoured over large-scale operations ebcause of romantic notions of rugged small operators battling both the elements and anonymous corporations. [They ought to be supported] because of the scientific evidence available to confirm the common-sense inference that local fishers, if given privileged access, will tend to avoid trashing their local stocks, while foreign fishers do not have such motivation.

My practise as a scientist is atheistic. That is to say, when I set up an experiment I assume that no god, angel, or devil is going to interfere with its course; and this assumption has been justified by such success as I have achieved in my professional career. I should therefore be intellectually dishonest if I were not also atheistic in the affairs of the world. And I should be a coward if I did not state my theoretical views in public.

Without seeing any reason to believe that women are, on the average, so strong physically, intellectually, or morally, as men, I cannot shut my eyes to the fact that many women are much better endowed in all these respects than many men, and I am at a loss to understand on what grounds of justice or public policy a career which is open to the weakest and most foolish of the male sex should be forcibly closed to women of vigor and capacity.

If all persons with any trace of homosexual history, or those who were predominantly homosexual, were eliminated from the population today, there is no reason for believing that the incidence of the homosexual in the next generation would be materially reduced. The homosexual has been a significant part of human sexual activity since the dawn of history, primarily because it is an expression of capacities that are basic in the human animal.

We don't even know what species are out there, for the most part, particularly when you get down to the microbes and very small invertebrates. They make up the mass of the organisms around us, including the soil we depend on, the soil of cornfields as well as hardwood forests. We haven't taken ecology to the point where we can even make a crude prediction of what's going to happen when we've reduced the living world down to a certain level.

Science seems to me to teach in the highest and strongest manner the great truth which is embodied in the Christian conception of entire surrender to the will of God. Sit down before fact as a little child, be prepared to give up every preconceived notion, follow humbly wherever and to whatever abysses nature leads, or you shall learn nothing. I have only begun to learn content and peace of mind since I have resolved at all risks to do this.

To a person uninstructed in natural history, his country or sea-side stroll is a walk through a gallery filled with wonderful works of art, nine-tenths of which have their faces turned to the wall. Teach him something of natural history, and you place in his hands a catalogue of those which are worth turning around. Surely our innocent pleasures are not so abundant in this life, that we can afford to despise this or any other source of them.

That's the way to get young people. Once they see there are wonderful things to hunt for, to rediscover a species that was thought to be extinct or is extremely rare, to be the first to see a nest, to discover a new species unsuspected close to your home - these are things, I think, with a little education and excitement and the right kind of natural history would actually start a movement that makes going back to nature a profitable adventure.

One may well find oneself beginning to doubt whether all this could conceivably be the product of an enormous lottery presided over by natural selection, blindly picking the rare winners from among numbers drawn at utter random...nevertheless although the miracle of life stands "explained" it does not strike us as any less miraculous. As Francois Mauriac wrote, What this professor says is far more incredible than what we poor Christians believe.

The idea that we are "stewards of the earth" is another symptom of human arrogance. Imagine yourself with the task of overseeing your body's physical processes. Do you understand the way it works well enough to keep all its systems in operation? Can you make your kidneys function? Can you control the removal of waste? Are you conscious of the blood flow through your arteries, or the fact that you are losing a hundred thousand skin cells a minute?

A paradigm shift is the best a scientist can hope for. Whenever I smell an opportunity like that, I go after it. You have a new discovery that something's working in a different way than you thought. And this is particularly true in molecular and cell biology, which is structural biology and has the least potential for controversy and partisanship among the biological scientists. You're dealing with a concrete object that's either there or not there.

Most people are surprised when they hear my somber figures: we know of 2 million species of plants, animals and microorganisms, and we can give them each a scientific name and a diagnostic description. We know, perhaps generously, more than just a little bit of the anatomy in no more than 10 percent. We have done thorough studies in fewer than one-tenth of 1 percent. And the total number of species on Earth is unknown to the nearest order of magnitude.

If I was diagnosed with something that was fatal in the next couple of years, I can't imagine anything more terrifying. And so for me, we know a lot about technology and we know a lot about the world, but I think health is the one area where there's so much data, but it's chaotic and that it's still a big black box. So, understanding really what is going to make me healthy and what is going to allow me to live the longest life is definitely keeps me up.

Human existence may be simpler than we thought. There is no predestination, no unfathomed mystery of life. Demons and gods do not vie for our allegiance. Instead, we are self-made, independent, alone, and fragile, a biological species adapted to live in a biological world. What counts for long-term survival is intelligent self-understanding, based upon a greater independence of thought than that tolerated today even in our most advanced democratic societies.

On the lawn next to the sidewalk a fire ant colony is swarming. The ants are pouring out of a mound nest, here no more than an irregular pile of dirt partly flattened by the last pass of a lawnmower. Winged queens and males are taking off on their nuptial flight, protected by angry-looking workers that run up and down the grass blades and out onto the blistering-hot concrete of the sidewalk. The species is unmistakably Solenopsis geminata, the native fire ant.

There is a strong current in contemporary culture advocating ' holistic ' views as some sort of cure-all... Reductionism implies attention to a lower level while holistic implies attention to higher level. These are intertwined in any satisfactory description: and each entails some loss relative to our cognitive preferences, as well as some gain... there is no whole system without an interconnection of its parts and there is no whole system without an environment.

...the scientific attitude implies what I call the postulate of objectivity-that is to say, the fundamental postulate that there is no plan, that there is no intention in the universe. Now, this is basically incompatible with virtually all the religious or metaphysical systems whatever, all of which try to show that there is some sort of harmony between man and the universe and that man is a product-predictable if not indispensable-of the evolution of the universe.

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