Future is not extrapolation of past

You have to invent the future you want.

Every big problem is a big opportunity.

How would you compete against yourself?

No one will pay you to solve a non-problem.

Who cares if companies are overvalued or not?

The probability of failure doesn't matter to me.

People over 45 basically die in terms of new ideas.

My life is full of way more mistakes than successes.

Big data will replace the need for 80% of all doctors

If everyone played it safe, we wouldn't get anywhere.

Your willingness to fail is what will let you succeed.

My willingness to fail gives me the ability to succeed.

Not thinking it's possible is a failure of imagination.

The willingness to fail gives us the freedom to succeed.

We humans think linearly but tech trends are exponential.

I don't know a startup that hasn't been through tough times.

If I wanted to be a doctor today I'd go to math school not med school.

I challenge anybody to claim that clean tech done right is a disaster.

If you're going to re-invent healthcare you have to start from scratch.

I don’t mind failing, but if I succeed it better be worth succeeding for.

I believe a board in a small startup company should never vote on anything.

I've failed at more things than anyone I know. No one remembers the failures.

Where most entrepreneurs fail is on the things they don't know they don't know.

Any problem is an opportunity. The bigger the problem, the bigger the opportunity.

I don’t mind the low probability of success, but it better be impactful if we do succeed.

You need a degree of foolishness to cause disruptive change in healthcare. Dare to dream.

One of the best things data can enable us to do is to ask questions we didn't know to ask.

The first rule of venture capitalism is hands-on experience. You have to get your hands dirty.

Everybody else is afraid to fail. I do not really care because when I fail, I try something new.

Climate deniers are clearly the fringe group and need to see a proctologist to find their heads.

Electric cars are coal-powered cars. Their carbon emissions can be worse than gasoline-powered cars.

Your cellphone has 10 sensors, and your car has 400. But your body has none - that's going to change.

Spreadsheets are fiction. Believing in what you're doing and what you're building is what's important.

One thing about technology is that there's always a win, place, and show, and everyone else goes under.

Success comes to those that dare to dream dreams and are foolish enough to try and make them come true.

The U.S. has fallen well behind Europe in recognizing climate change and the implications of climate change.

We don't need a fuel that's cleaner, we need a fuel that happens to be cleaner, but is half the price of oil.

The world is hung up on food-based biofuels. Not only are they the wrong thing, they're the uneconomic thing.

Knowing whose advice to take and on what topic is the single most important decision an entrepreneur can make.

The combination of brilliant ideas and entrepreneurial spirit should lead us to a safer and more secure future.

I believe cellulosic fuels, biofuels made from nonfood crops are the only solution that will make a difference.

Eighty percent of what doctors do, tech can do at a fraction of the cost - especially your rural doctor in India.

The state of healthcare today is that we are busy in the practice of medicine vs. being in the science of medicine.

Nobody who comes in once every six weeks while you're working 80 or 90 hours a week is qualified to make a decision.

An entrepreneur is someone who dares to dream the dreams and is foolish enough to try to make those dreams come true.

In the next 10 years, data science and software will do more for medicine than all of the biological sciences together.

Oil replacements and then efficiencies in engines and housing and the way we build houses is a very interesting market.

Screw up often; but screw up ahead of everybody else, and than learn as much, and than use it to make subsequent investments.

I'm not a political person. I'm a techie nerd, and I enjoy the techie part. I mean, all my life, I've loved great technology.

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