We as human beings like to be cocksure and certain.

Once you start looking at the world rationally, it becomes much more exciting.

I have spent a reasonable percentage of my life in libraries - I like the hush.

I have a theory that evolutionary biologists are more vain than particle physicists.

My life is constant revision but it's not revision, a lot of it is for the first time.

To be paid, to be employed to be an enthusiast and be excited about existence is fantastic.

Homeopaths do not have a physical brain, but merely 'skull water' with the memory of brains.

Wherever you are on Earth, there is more life present than in the rest of the known universe.

Not since Jimmy Carr have I seen a cold computer programme on stage generate so much laughter.

They gave 12 monkeys a typewriter for a week, and after a week, they only used it as a bathroom.

I want to create shows which are interesting. I hope that some people are excited by some of the ideas.

Life, to me personally, I believe it is a finite thing, my consciousness, and I want to use it as much as possible.

If the Royal Variety Show was put in a matter transportation machine with the Royal Institution Christmas lectures, this is what you'd get.

There can be a science to joke writing, there are certainly rules and patterns that can be followed, but I think most of the best comedy goes beyond the rules.

I'm glad the universe is pointless. It means if I get to the end of my life, the universe can't turn to me and go, 'What have you been doing, you idiot? That's not the point!

My wife could turn to me and she may say, 'Why do you love me?' And I can with all honesty look her in the eye and say, 'Because our pheromones matched our olfactory receptors.'

I have a problem with telling jokes about physics. Quite often the audience have no idea what you are talking about and, to be honest, I don't know what I'm talking about either.

The worst, the most difficult thing I think is that the more you become intrigued by science and the information is out there, the more you are aware of the paucity of your own knowledge.

We very quickly forget about the wonderful things we've got. People lose their excitement because there's too much. Basically we're experiencing nothing, because everything is available to us.

Science is very cross-generational; you're not just aiming it at twentysomethings, or eightysomethings. Every town's got a really broad selection of people and age groups interested in science.

I thought I better warn you that I am not one of those politically correct comedians, but it turns out that also I'm not really that racist, homophobic or woman hating either, so you might not notice

You always need to find the balance in the science, but the balance to talking about evolutionary theory is not to talk about creationism, that's not a balance, that's misleading and it's just wrong.

I have a very vibrant imposter syndrome that goes on throughout most of my life, but nothing more than when someone has to put a hat on me or some kind of sash and go, 'We're giving you this certificate.'

As much as of course that Englishness of always to be embarrassed about any sense of complement, it is nice to know that a lot of the projects that I've worked on that people do feel there has been some effect.

I don't have any hobbies because my working job is my hobby. What I do is I spend my whole time looking through telescopes and having brain scans and buying books about various different ideas and I just sit around, that's my life.

The main battle is to make people realise that doubt is important. Doubt is good. The 'don't know' answer sometimes is the box you should tick, and it's about not being scared about that fact. Even the greatest minds don't know everything.

I am not man or beast; I am bibliosexual, and a seedy bibliosexual who haunts the streets, laden with carrier bags held by blistered fingers, stooping under the weight of the rucksack that has brought on sciatica and a Dickensian demeanour.

One idea I explore in my stand-up show is whether, if you try looking at the universe rationally and avoid coping mechanisms like mysticism or religion, you can still be happy knowing you are going to die after a brief time on this spinning ball.

If you really want space on public transport you should carry some pornography from the 1970s and a pair of children's safety scissors, then delicately cut out all the eyes of the glamour models whilst whistling. Every now and again mutter, 'Why are women more beautiful when they are eyeless?' You will be able to stretch out, though this can have ramifications such as ending up on a police list or being run out of town.

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