The explosion would be just the right size to maximize the amount of paperwork your lab would face. If the explosion were smaller, you could potentially cover it up. If it were larger, there would be no one left in the city to submit paperwork to.

I have always had trouble paying attention. When I was supposed to be at work, I'd be doodling. But then when I was home, trying to draw, I would be working on math problems. I never end up doing exactly what I should be doing at at any given time.

I'm not sure why we romanticize 'young love,' or love in general...It just leads to the idea that either your love is pure, perfect and eternal, and you are storybook-compatible in every way with no problems, or you're LYING when you say 'I love you.

If 'other people have experiences incorrectly' is annoying to you, think how unbearable it must be to have a condescending stranger tell you they hate the way you're experiencing your life at just the moment you've found something you want to remember.

There are definitely times - and I think this is pretty common among cartoonists - where you spend an entire day trying to think of an idea, and you're like, 'I give up.' And then you go and take a shower or run an errand, and halfway there, you get an idea.

Some of the first infographics I did started off as notes to myself: trying to plot out, for instance, how IP addresses are allocated. After a while, I thought, 'This is a neat thing I can share with people, and they can follow me along in that process of understanding.'

People often say, 'I like your comics, even though I don't know enough math to get all of them,' as if it's some kind of club where they don't belong. But there's no club. There's just lots of people who are excited about thinking, learning, joking, and sometimes overanalyzing things.

I think the really cool and compelling thing about math and physics is that it opens up entry to all these hypotheticals - or at least, it gives you the language to talk about them. But at the same time, if a scenario is completely disconnected from reality, it's not all that interesting.

Space is about 100 kilometers away. That’s far away—I wouldn’t want to climb a ladder to get there—but it isn’t that far away. If you’re in Sacramento, Seattle, Canberra, Kolkata, Hyderabad, Phnom Penh, Cairo, Beijing, central Japan, central Sri Lanka, or Portland, space is closer than the sea.

I think the comic that's gotten me the most feedback is actually the one about the stoplights. Noticing when the stoplights are in sync, or calculating the length of your strides between floor tiles - normal people notice that kind of stuff, but a certain kind of person will do some calculations.

I used to work at NASA in Virginia. It was nothing glamorous; I was just tasked with making code compile for obscure projects, and I wasn't very good at it. Now I spend most of my time drawing pictures and looking at funny things on the Internet, which in retrospect is largely what I did at my old job, too.

I have no artistic training - as you might have guessed from all the stick figures! - and there are a few things I have a really hard time drawing. I think the one that comes up the most is airplanes. Big airliners have such a weird wing shape, and I always have to redraw them 20 times before they're even recognizable.

What people don't appreciate, when they picture Terminator-style automatons striding triumphantly across a mountain of human skulls, is how hard it is to keep your footing on something as unstable as a mountain of human skulls. Most humans probably couldn't manage it, and they've had a lifetime of practice at walking without falling over.

Take wrong turns. Talk to strangers. Open unmarked doors. And if you see a group of people in a field, go find out what they are doing. Do things without always knowing how they'll turn out. You're curious and smart and bored, and all you see is the choice between working hard and slacking off. There are so many adventures that you miss because you're waiting to think of a plan. To find them, look for tiny interesting choices. And remember that you are always making up the future as you go.

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