Today's 'best practices' lead to dead ends; the best paths are new and untried.

Under perfect competition, in the long run no company makes an economic profit.

A lot of the key to Apple's succes is Designing technology in order to hide it.

Recruiting is a core competency for any company. It should never be outsourced.

It's a horribly mismanaged company-probably a lot of pot smoking going on there.

Our society, the dominant culture doesn't like science. It doesn't like technology.

You don't want to just do 'me too' companies that are copying what others are doing.

Creating value isn't enough - you also need to capture some of the value you create.

The most contrarian thing of all is not to oppose the crowd but to think for yourself.

In a world of scarce resources, globalization without new technology is unsustainable.

The lowest-hanging fruit in preventative medicine is just to really focus on nutrition.

Every business is successful exactly to the extent that it does something others cannot.

I don't think success is complicated; if you do something that works, then it's a success.

When people use the word 'science,' it's often a tell, like in poker, that you're bluffing.

You want to be the last company in a category. Those are the ones that are really valuable.

Big part of the challenge to innovation is that people too easily resign themselves to dying.

An entrepreneur must deal with more uncertainty than a professional with a well-defined role.

Contrarian thinking doesn't make any sense unless the world still has secrets left to give up.

First, only invest in companies that have the potential to return the value of the entire fund.

Google makes so much money that it’s now worth three times more than every U.S. airline combined.

I believe if we could enable people to live forever, we should do that. I think this is absolute.

Darwinism may be a fine theory in other contexts, but in startups, intelligent design works best.

The most successful businesses have an idea for the future that's very different from the present.

One of my first investments was $100,000 in a Web-based calendar startup - and I lost every dollar.

You will never build a company on the scale of a Facebook or a Google if you sell it along the way.

There's always a sense that people will do things quite differently if they think they have privacy.

Rivalry causes us to overemphasize old opportunities and slavishly copy what has worked in the past.

I'm not a politician. But neither is Donald Trump. He is a builder, and it's time to rebuild America.

Probably the most extreme form of inequality is between people who are alive and people who are dead.

Wall Street is always too biased toward short-term profitability and biased against long-term growth.

People are worried about privacy, and its one of the reasons people are using a service like SnapChat.

People are spending way too much time thinking about climate change, way too little thinking about AI.

I do tend to think that things that have incredibly long time horizons often do involve market failures.

I think what's always important is not to be contrarian for its own sake but to really get at the truth.

Higher education holds itself out as a kind of universal church, outside of which there is no salvation.

As you craft a plan to expand to adjacent markets, don't disrupt: Avoid competition as much as possible.

I think society is both something that's very real and very powerful, but on the whole quite problematic.

There's no single right place to be an entrepreneur, but certainly there's something about Silicon Valley.

All of us have to work toward a definite future... that can motivate and inspire people to change the world.

If people were super-optimistic about technology there would be no reason to be pessimistic about the future.

We cannot take for granted that the future will be better, and that means we need to work to create it today.

Every correct answer is necessarily a secret: something important and unknown, something hard to do but doable.

If you can identify a delusional popular belief, you can find what lies hidden behind it: the contrarian truth.

I do think Bitcoin is the first [encrypted money] that has the potential to do something like change the world.

What is it about our society where anyone who does not have Asperger's gets talked out of their heterodox ideas?

Most people are average. Founders are not. Founders' traits seem to have an inverse normal distribution to them.

Properly defined, a startup is the largest group of people you can convince of a plan to build a different future.

Unsolved problems are where you'll find opportunity. Energy is one sector with extremely urgent unsolved problems.

College gives people learning and also takes away future opportunities by loading the next generation down with debt.

If you have a business idea that's extremely easy to copy, that can often become something of a challenge or problem.

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