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Learn, compare, collect the facts!
Learn the ABC of science before you try to ascend to its summit.
The gastric laboratory uses its protein ferment under an acid reaction.
Perfect as the wing of a bird may be, it will never enable the bird to fly.
While you are experimenting, do not remain content with the surface of things.
Don't become a mere recorder of facts, but try to penetrate the mystery of their origin.
Appetite, craving for food, is a constant and powerful stimulator of the gastric glands.
But man has still another powerful resource: natural science with its strictly objective methods.
Men are apt to be much more influenced by words than by the actual facts of the surrounding reality
Physiology has, at last, gained control over the nerves which stimulate the gastric glands and the pancreas.
It is still open to question whether psychology is a natural science, or whether it can be regarded as a science at all.
As we have seen, bread, and especially dry bread, evokes secretion of considerably larger quantities of saliva than meat.
School yourself to demureness and patience. Learn to inure yourself to drudgery in science. Learn, compare, collect the facts.
Never think that you already know all. However highly you are appraised, always have the courage to say to yourself-I am ignorant.
Do not become archivists of facts. Try to penetrate to the secret of their occurrence, persistently search for the laws which govern them.
Science demands from a man all his life. If you had two lives that would not be enough for you. Be passionate in your work and in your searching.
The Sun-Paul must consider only one thing: what is the relation of this or that external reaction of the animal to the phenomena of the external world?
Gradualness, gradualness, and gradualness. From the very beginning of your work, school yourself to severe gradualness in the accumulation of knowledge.
Only by observing this condition would the results of our work be regarded as fully conclusive and as having elucidated the normal course of the phenomena.
From the described experiment it is clear that the mere act of eating, the food even not reaching the stomach, determines the stimulation of the gastric glands.
Perfect as the wing of a bird may be, it will never enable the bird to fly if unsupported by the air. Facts are the air of science. Without them a man of science can never rise.
It is not accidental that all phenomena of human life are dominated by the search for daily bread - the oldest link connecting all living things, man included, with the surrounding nature.
When the dog is repeatedly teased with the sight of objects inducing salivary secretion from a distance, the reaction of the salivary glands grows weaker and weaker and finally drops to zero.
Our experiments not only proved the existence of a nervous apparatus in the above-mentioned glands, but also disclosed some facts clearly showing the participation of these nerves in normal activity.
As was to be expected, the discovery of the nervous apparatus of the salivary glands immediately impelled physiologists to seek a similar apparatus in other glands lying deeper in the digestive canal.
In the case of the stomach, however, the nerves of the glandular cells were always severed when constructing an artificially isolated pouch and this, naturally, affected the normal work of the stomach.
The physiologist who succeeds in penetrating deeper and deeper into the digestive canal becomes convinced that it consists of a number of chemical laboratories equipped with various mechanical devices.
Edible substances evoke the secretion of thick, concentrated saliva. Why? The answer, obviously, is that this enables the mass of food to pass smoothly through the tube leading from the mouth into the stomach.
The digestive canal represents a tube passing through the entire organism and communicating with the external world, i.e. as it were the external surface of the body, but turned inwards and thus hidden in the organism.
Our success was mainly due to the fact that we stimulated the nerves of animals that easily stood on their own feet and were not subjected to any painful stimulus either during or immediately before stimulation of their nerves.
Thanks to our present surgical methods in physiology we can demonstrate at any time almost all phenomena of digestion without the loss of even a single drop of blood, without a single scream from the animal undergoing the experiment.
Possibilities are like the wings of birds; they allow man to soar and to climb to the heavens. And facts are like the atmosphere against which those wings must beat, and without which the soaring bird will surely plummet back to earth.
It is clear to all that the animal organism is a highly complex system consisting of an almost infinite series of parts connected both with one another and, as a total complex, with the surrounding world, with which it is in a state of equilibrium.
It has long been known for sure that the sight of tasty food makes a hungry man's mouth water; also lack of appetite has always been regarded as an undesirable phenomenon, from which one might conclude that appetite is essentially linked with the process of digestion.
It goes without saying that the desire to accomplish the task with more confidence, to avoid wasting time and labour, and to spare our experimental animals as much as possible, made us strictly observe all the precautions taken by surgeons in respect to their patients.
Finally, as the digestive canal is a complex system, a series of separate chemical laboratories, I cut the connections between them in order to investigate the course of phenomena in each particular laboratory; thus I resolved the digestive canal into several separate parts.
I am convinced that an important stage of human thought will have been reached when the physiological and the psychological, the objective and the subjective, are actually united, when the tormenting conflicts or contradictions between my consciousness and my body will have been factually resolved or discarded.
Mankind will possess incalculable advantages and extraordinary control over human behavior when the scientific investigator will be able to subject his fellow men to the same external analysis he would employ for any natural object, and when the human mind will contemplate itself not from within but from without.
If we could look through the skull into the brain of a consciously thinking person, and if the place of optimal excitability were luminous, then we should see playing over the cerebral surface, a bright spot with fantastic, waving borders constantly fluctuating in size and form, surrounded by a darkness more or less deep, covering the rest of the hemisphere.
One can truly say that the irresistible progress of natural science since the time of Galileo has made its first halt before the study of the higher parts of the brain, the organ of the most complicated relations of the animal to the external world. And it seems, and not without reason, that now is the really critical moment for natural science; for the brain, in its highest complexity-the human brain-which created and creates natural science, itself becomes the object of this science.
The digestive canal is in its task a complete chemical factory. The raw material passes through a long series of institutions in which it is subjected to certain mechanical and, mainly, chemical processing, and then, through innumerable side-streets, it is brought into the depot of the body. Aside from this basic series of institutions, along which the raw material moves, there is a series of lateral chemical manufactories, which prepare certain reagents for the appropriate processing of the raw material.
In the dog two conditions were found to produce pathological disturbances by functional interference, namely, an unusually acute clashing of the excitatory and inhibitory processes, and the influence of strong and extraordinary stimuli. In man precisely similar conditions constitute the usual causes of nervous and psychic disturbances. Different conditions productive of extreme excitation, such as intense grief or bitter insults, often lead, when the natural reactions are inhibited by the necessary restraint, to profound and prolonged loss of balance in nervous and psychic activity.