Venice is the prettiest city I've ever seen. It looks like a Disneyland ride.

I would vote for Johnny Depp. We could use a president that could swashbuckle.

I think anyone who is famous is a moron if they're on Twitter. It's just stupid.

I don't like to share my personal life... it wouldn't be personal if I shared it.

The owner of a local cannabis café told reporters George Clooney was no stranger there.

You have only a short period of time in your life to make your mark, and I'm there now.

I'm always sort of optimistic about how good we are, as a country, at fixing ourselves.

Directing is really exciting. In the end, it's more fun to be the painter than the paint.

I'm interested in making films that ask questions and don't particularly provide answers.

It's hard to find actors that don't feel contemporary when you put them in a period piece.

The problem is, we elected a manager and we need a leader. Let's face it: Bush is just dim.

'Ides of March' I did for scale - scale as a director, scale as an actor, scale as a writer.

"Is Art worth dying for?" Well I don't know a single inanimate object that's worth dying for.

I have a real interest in pushing some of the limits of things that studios don't want to make.

It's incredibly unfair. You don't see a lot of 60-year-old women with 20-year-old men onscreen.

Things hurt me now. My knees hurt, my back hurts. But your head still thinks it's twenty-three.

So far I've done two films that have basically been about television because I know that world.

Art takes different forms... But it represents something that is basic in all of us-our history.

Most of the films I've done haven't done particularly well. I'm surprised I'm continuing to work.

I enjoy going on motorcycle trips and stopping in small towns and enjoying drinks with the locals.

I'm a Method actor. I spent years training for the drinking and carousing I had to do in this film.

It's not about an opening weekend. It's about a career, building a set of films you're proud of. Period.

Whatever you do, don’t wake up at 65 years old and think about what you should have done with your life.

If you're going to do a romantic comedy it was about housing it in something that we haven't seen before.

Ninety percent of films are pretty mediocre, but they have a built-in audience and open on 3,000 screens.

I don't think that Hollywood will have much to do with changing politics. Hollywood usually reflects things.

My little animal secrets must remain my little animal secrets. How I do my nails, that is really my business.

If you don't drink coffee, I am suspicious of your character and will not invite you to my Italian lake home.

Over the years, over the history of our country, liberals have stood on many of the right sides of the issues.

After doing One Fine Day and playing a pediatrician on ER, I'll never have kids. I'm going to have a vasectomy.

It's possible for me to make a bad movie out of a good script, but I can't make a good movie from a bad script.

I watch 'Batman & Robin' from time to time. It's the worst movie I ever made, so it's a good lesson in humility.

Run for office? No. I've slept with too many women, I've done too many drugs, and I've been to too many parties.

I grew up in the world of bad television, on my dad's sets and then as a young schmuck on dating shows and so on.

I just found out about 10 days ago that I must live 300 or 400 yards from Britney Spears... so now I have to move.

If you're famous, I don't - for the life of me - I don't understand why any famous person would ever be on Twitter.

I don't know if winning at any cost is wrong or not. There are times I've thought that the end justified the means.

I enjoy directing. I don't know whether it's improving or not, but it's certainly evolving in different directions.

Who would name their kid Jack with the last words 'off' at the end of the last name? No wonder that guy is screwed up.

The simple truth is that everyone has an opinion, everyone has the right to voice it, and they should if they want to.

I am the least qualified person to comment on anyone playing the role of Batman since I so terribly destroyed the part.

I don't care. Charlton Heston is the head of the National Rifle Association. He deserves whatever anyone says about him.

If I had been with all the women that I was said to have been with, I wouldn't have had the time to shoot a single movie!

I do happen to have a good life... But I also like to work. I feel like I got the brass ring and I got very lucky in this.

Stage actors look down on movie actors, movie actors look down on TV actors, and TV actors look down on... mass murderers.

I've been in relationships where I've felt terribly alone. Just because you're with someone, it doesn't mean you're happy.

If you try desperately to hang on to something that used to be a success for you, it's going to go away. You have to change.

I can't give you 150 takes. I can't even give you 30 different ways of doing it! I don't have the talent or the range for it.

I get asked a lot about getting into politics. I say, 'Take a look at politics. You tell me what seems appealing about that.'

I had to stop going to auditions thinking, 'Oh, I hope they like me.' I had to go in thinking I was the answer to their problem.

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